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While multiple instance learning (MIL) has shown to be a promising approach for histopathological whole slide image (WSI) analysis, its reliance on permutation invariance significantly limits its capacity to effectively uncover semantic…

Image and Video Processing · Electrical Eng. & Systems 2025-07-14 Xiwen Chen , Peijie Qiu , Wenhui Zhu , Hao Wang , Huayu Li , Xuanzhao Dong , Xiaotong Sun , Xiaobing Yu , Yalin Wang , Abolfazl Razi , Aristeidis Sotiras

Most existing robust fitting methods are designed for classical models, such as lines, circles, and planes. In contrast, fewer methods have been developed to robustly handle non-classical models, such as spiral curves, procedural character…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Zongliang Zhang , Shuxiang Li , Xingwang Huang , Zongyue Wang

The whole slide image (WSI) classification is often formulated as a multiple instance learning (MIL) problem. Since the positive tissue is only a small fraction of the gigapixel WSI, existing MIL methods intuitively focus on identifying…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenhao Tang , Sheng Huang , Xiaoxian Zhang , Fengtao Zhou , Yi Zhang , Bo Liu

Probabilistic graphical models (PGMs) are widely used to discover latent structure in data, but their success hinges on selecting an appropriate model design. In practice, model specification is difficult and often requires iterative…

Machine Learning · Computer Science 2026-04-08 Kevin Zhang , Yixin Wang

We propose a deep network that can be trained to tackle image reconstruction and classification problems that involve detection of multiple object instances, without any supervision regarding their whereabouts. The network learns to extract…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Baptiste Angles , Yuhe Jin , Simon Kornblith , Andrea Tagliasacchi , Kwang Moo Yi

Labeling data for classification requires significant human effort. To reduce labeling cost, instead of labeling every instance, a group of instances (bag) is labeled by a single bag label. Computer algorithms are then used to infer the…

Machine Learning · Statistics 2014-11-18 Anh T. Pham , Raviv Raich , Xiaoli Z. Fern

In meta-learning approaches, it is difficult for a practitioner to make sense of what kind of representations the model employs. Without this ability, it can be difficult to both understand what the model knows as well as to make meaningful…

Machine Learning · Computer Science 2022-04-05 Pedro Sandoval-Segura , Wallace Lawson

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Multi-instance learning is a type of weakly supervised learning. It deals with tasks where the data is a set of bags and each bag is a set of instances. Only the bag labels are observed whereas the labels for the instances are unknown. An…

Machine Learning · Computer Science 2021-05-05 Weijia Zhang

Prototypical part learning is emerging as a promising approach for making semantic segmentation interpretable. The model selects real patches seen during training as prototypes and constructs the dense prediction map based on the similarity…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Hugo Porta , Emanuele Dalsasso , Diego Marcos , Devis Tuia

Attaining prototypical features to represent class distributions is well established in representation learning. However, learning prototypes online from streaming data proves a challenging endeavor as they rapidly become outdated, caused…

Computer Vision and Pattern Recognition · Computer Science 2021-10-20 Matthias De Lange , Tinne Tuytelaars

Class Incremental Learning (CIL) based on pre-trained models offers a promising direction for open-world continual learning. Existing methods typically rely on correlation-based strategies, where an image's classification feature is used as…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Libo Huang , Zhulin An , Chuanguang Yang , Boyu Diao , Fei Wang , Yan Zeng , Zhifeng Hao , Yongjun Xu

Diffusion models are generative models that have shown significant advantages compared to other generative models in terms of higher generation quality and more stable training. However, the computational need for training diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Gulcin Baykal , Halil Faruk Karagoz , Taha Binhuraib , Gozde Unal

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Multiple instance learning (MIL) is often used in medical imaging to classify high-resolution 2D images by processing patches or classify 3D volumes by processing slices. However, conventional MIL approaches treat instances separately,…

Machine Learning · Computer Science 2025-11-13 Ethan Harvey , Dennis Johan Loevlie , Michael C. Hughes

Multiple instance learning (MIL) is a framework for weakly supervised classification, where labels are assigned to sets of instances, i.e., bags, rather than to individual data points. This paradigm has proven effective in tasks where…

Machine Learning · Computer Science 2026-03-03 Salome Kazeminia , Carsten Marr , Bastian Rieck

Positive instance detection, especially for these in positive bags (true positive instances, TPIs), plays a key role for multiple instance learning (MIL) arising from a specific classification problem only provided with bag (a set of…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Dongkuan Xu , Jia Wu , Wei Zhang , Yingjie Tian

Interpretable rationales for model predictions play a critical role in practical applications. In this study, we develop models possessing interpretable inference process for structured prediction. Specifically, we present a method of…

Computation and Language · Computer Science 2020-05-01 Hiroki Ouchi , Jun Suzuki , Sosuke Kobayashi , Sho Yokoi , Tatsuki Kuribayashi , Ryuto Konno , Kentaro Inui

The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Recognizing relations between entities is a pivotal task of relational learning. Learning relation representations from distantly-labeled datasets is difficult because of the abundant label noise and complicated expressions in human…

Computation and Language · Computer Science 2021-03-23 Ning Ding , Xiaobin Wang , Yao Fu , Guangwei Xu , Rui Wang , Pengjun Xie , Ying Shen , Fei Huang , Hai-Tao Zheng , Rui Zhang
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