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Breast-Conserving Surgery (BCS) requires precise intraoperative margin assessment to preserve healthy tissue. Deep Ultraviolet Fluorescence Scanning Microscopy (DUV-FSM) offers rapid, high-resolution surface imaging for this purpose;…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Pouya Afshin , David Helminiak , Tianling Niu , Julie M. Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Microscopic examination of slides prepared from tissue samples is the primary tool for detecting and classifying cancerous lesions, a process that is time-consuming and requires the expertise of experienced pathologists. Recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Saba Fatema , Brighton Nuwagira , Sayoni Chakraborty , Reyhan Gedik , Baris Coskunuzer

Accurate skin disease classification is a critical yet challenging task due to high inter-class similarity, intra-class variability, and complex lesion textures. While deep learning-based computer-aided diagnosis (CAD) systems have shown…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Enam Ahmed Taufik , Abdullah Khondoker , Antara Firoz Parsa , Seraj Al Mahmud Mostafa

Human immune system contains white blood cells (WBC) that are good indicator of many diseases like bacterial infections, AIDS, cancer, spleen, etc. White blood cells have been sub classified into four types: monocytes, lymphocytes,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Rabia Asghar , Arslan Shaukat , Usman Akram , Rimsha Tariq

The classification of white blood cells (WBCs) from peripheral blood smears is critical for the diagnosis of leukemia. However, automated approaches still struggle due to challenges including class imbalance, domain shift, and morphological…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Antony Gitau , Martin Paulson , Bjørn-Jostein Singstad , Karl Thomas Hjelmervik , Ola Marius Lysaker , Veralia Gabriela Sanchez

Hepatocellular carcinoma is the most spread primary liver cancer across the world ($\sim$80\% of the liver tumors). The gold standard for HCC diagnosis is liver biopsy. However, in the clinical routine, expert radiologists provide a visual…

Computer Vision and Pattern Recognition · Computer Science 2025-01-15 E. Sarfati , A. Bône , M-M. Rohé , C. Aubé , M. Ronot , P. Gori , I. Bloch

Cervical cancer remains a significant global health concern and a leading cause of cancer-related deaths among women. Early detection through Pap smear tests is essential to reduce mortality rates; however, the manual examination is time…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nisreen Albzour , Sarah S. Lam

Cervical intraepithelial neoplasia (CIN) grade of histopathology images is a crucial indicator in cervical biopsy results. Accurate CIN grading of epithelium regions helps pathologists with precancerous lesion diagnosis and treatment…

Image and Video Processing · Electrical Eng. & Systems 2019-07-26 Yuan Xue , Qianying Zhou , Jiarong Ye , L. Rodney Long , Sameer Antani , Carl Cornwell , Zhiyun Xue , Xiaolei Huang

Accurate classification of focal liver lesions is crucial for diagnosis and treatment in hepatology. However, traditional supervised deep learning models depend on large-scale annotated datasets, which are often limited in medical imaging.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Song Jian , Hu Yuchang , Wang Hui , Chen Yen-Wei

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

Histopathological images are the gold standard for diagnosing liver cancer. However, the accuracy of fully digital diagnosis in computational pathology needs to be improved. In this paper, in order to solve the problem of multi-label and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Liangrui Pan , Yutao Dou , Zhichao Feng , Liwen Xu , Shaoliang Peng

Breast cancer is one of the most serious types of cancer that can occur in women. The automatic diagnosis of breast cancer by analyzing histological images (HIs) is important for patients and their prognosis. The classification of HIs…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hayder A. Khikani , Naira Elazab , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Multi-Label Image Classification (MLIC) approaches usually exploit label correlations to achieve good performance. However, emphasizing correlation like co-occurrence may overlook discriminative features of the target itself and lead to…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Jiazhi Xu , Sheng Huang , Fengtao Zhou , Luwen Huangfu , Daniel Zeng , Bo Liu

Objective: Cytology plays a crucial role in lung cancer diagnosis. Pulmonary cytology involves cell morphological characterization in the specimen and reporting the corresponding findings, which are extremely burdensome tasks. In this…

Image and Video Processing · Electrical Eng. & Systems 2026-04-23 Atsushi Teramoto , Ayano Michiba , Yuka Kiriyama , Tetsuya Tsukamoto , Kazuyoshi Imaizumi , Hiroshi Fujita

Accurate classification of blood cells plays a key role in improving automated blood analysis for both medical and veterinary applications. This work presents a two-stage deep clustering method for classifying blood cells from…

Quantitative Methods · Quantitative Biology 2025-09-25 Mihaela Macarie-Ancau , Adrian Groza

Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Laura J. Tafe , Yevgeniy A. Linnik , Louis J. Vaickus , Naofumi Tomita , Saeed Hassanpour

The structural and spatial arrangements of cells within tissues represent their functional states, making graph-based learning highly suitable for histopathology image analysis. Existing methods often rely on fixed graphs with predefined…

Image and Video Processing · Electrical Eng. & Systems 2025-10-16 Sudipta Paul , Amanda W. Lund , George Jour , Iman Osman , Bülent Yener

Algorithmic decision support is rapidly becoming a staple of personalized medicine, especially for high-stakes recommendations in which access to certain information can drastically alter the course of treatment, and thus, patient outcome;…

Computer Vision and Pattern Recognition · Computer Science 2021-08-16 Haomin Chen , T. Y. Alvin Liu , Catalina Gomez , Zelia Correa , Mathias Unberath

Computational cytology is a critical, rapid-developing, yet challenging topic in the field of medical image computing which analyzes the digitized cytology image by computer-aided technologies for cancer screening. Recently, an increasing…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Hao Jiang , Yanning Zhou , Yi Lin , Ronald CK Chan , Jiang Liu , Hao Chen

Automatic detection of leukemic B-lymphoblast cancer in microscopic images is very challenging due to the complicated nature of histopathological structures. To tackle this issue, an automatic and robust diagnostic system is required for…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters