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In this article, we propose a novel regularization method for a class of nonlinear inverse problems that is inspired by an application in quantitative magnetic resonance imaging (qMRI). The latter is a special instance of a general…

Optimization and Control · Mathematics 2025-06-16 Guozhi Dong , Michael Hintermüller , Clemens Sirotenko

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi

Convolutional networks are successful, but they have recently been outperformed by new neural networks that are equivariant under rotations and translations. These new networks work better because they do not struggle with learning each…

Computer Vision and Pattern Recognition · Computer Science 2021-02-16 Philip Müller , Vladimir Golkov , Valentina Tomassini , Daniel Cremers

Knowledge of the noise distribution in magnitude diffusion MRI images is the centerpiece to quantify uncertainties arising from the acquisition process. The use of parallel imaging methods, the number of receiver coils and imaging filters…

Computer Vision and Pattern Recognition · Computer Science 2018-10-03 Samuel St-Jean , Alberto De Luca , Max A. Viergever , Alexander Leemans

We consider the problem of distributed dictionary learning, where a set of nodes is required to collectively learn a common dictionary from noisy measurements. This approach may be useful in several contexts including sensor networks.…

Machine Learning · Statistics 2013-04-15 Pierre Chainais , Cédric Richard

Diffusion weighted MRI (dMRI) provides a non invasive virtual reconstruction of the brain's white matter structures through tractography. Analyzing dMRI measures along the trajectory of white matter bundles can provide a more specific…

Quantitative Methods · Quantitative Biology 2019-06-21 Samuel St-Jean , Maxime Chamberland , Max A. Viergever , Alexander Leemans

Harmonization of T1-weighted MR images across different scanners is crucial for ensuring consistency in neuroimaging studies. This study introduces a novel approach to direct image harmonization, moving beyond feature standardization to…

Machine learning is a powerful approach for fitting microstructural models to diffusion MRI data. Early machine learning microstructure imaging implementations trained regressors to estimate model parameters in a supervised way, using…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Jason P. Lim , Stefano B. Blumberg , Neil Narayan , Sean C. Epstein , Daniel C. Alexander , Marco Palombo , Paddy J. Slator

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

We aim to leverage diffusion to address the challenging image matting task. However, the presence of high computational overhead and the inconsistency of noise sampling between the training and inference processes pose significant obstacles…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Yihan Hu , Yiheng Lin , Wei Wang , Yao Zhao , Yunchao Wei , Humphrey Shi

Deep learning algorithms utilizing magnetic resonance (MR) images have demonstrated cutting-edge proficiency in autonomously segmenting multiple sclerosis (MS) lesions. Despite their achievements, these algorithms may struggle to extend…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Jinwei Zhang , Lianrui Zuo , Blake E. Dewey , Samuel W. Remedios , Savannah P. Hays , Dzung L. Pham , Jerry L. Prince , Aaron Carass

Ultrasound is a widely accessible and cost-effective medical imaging tool commonly used for prenatal evaluation of the fetal brain. However, it has limitations, particularly in the third trimester, where the complexity of the fetal brain…

Image and Video Processing · Electrical Eng. & Systems 2025-04-04 Naomi Silverstein , Efrat Leibowitz , Ron Beloosesky , Haim Azhari

Conventional and deep learning-based methods have shown great potential in the medical imaging domain, as means for deriving diagnostic, prognostic, and predictive biomarkers, and by contributing to precision medicine. However, these…

The variability introduced by differences in MRI scanner models, acquisition protocols, and imaging sites hinders consistent analysis and generalizability across multicenter studies. We present a novel image-based harmonization framework…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Luca Caldera , Lara Cavinato , Francesca Ieva

Recently, diffusion models have gained significant attention as a novel set of deep learning-based generative methods. These models attempt to sample data from a Gaussian distribution that adheres to a target distribution, and have been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Chenyan Zhang , Yifei Chen , Zhenxiong Fan , Yiyu Huang , Wenchao Weng , Ruiquan Ge , Dong Zeng , Changmiao Wang

Deep learning holds immense promise for transforming medical image analysis, yet its clinical generalization remains profoundly limited. A major barrier is data heterogeneity. This is particularly true in Magnetic Resonance Imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Mehmet Yigit Avci , Pedro Borges , Virginia Fernandez , Paul Wright , Mehmet Yigitsoy , Sebastien Ourselin , Jorge Cardoso

Diffusion models (DMs) have recently gained attention with state-of-the-art performance in text-to-image synthesis. Abiding by the tradition in deep learning, DMs are trained and evaluated on the images with fixed sizes. However, users are…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Zhiyu Jin , Xuli Shen , Bin Li , Xiangyang Xue

Magnetic Resonance Imaging (MRI) is instrumental in clinical diagnosis, offering diverse contrasts that provide comprehensive diagnostic information. However, acquiring multiple MRI contrasts is often constrained by high costs, long…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Sanuwani Dayarathna , Kh Tohidul Islam , Bohan Zhuang , Guang Yang , Jianfei Cai , Meng Law , Zhaolin Chen

Data driven models for automated diagnosis in radiology suffer from insufficient and imbalanced datasets due to low representation of pathology in a population and the cost of expert annotations. Datasets can be bolstered through data…

Image and Video Processing · Electrical Eng. & Systems 2024-06-05 Colin Hansen , Simas Glinskis , Ashwin Raju , Micha Kornreich , JinHyeong Park , Jayashri Pawar , Richard Herzog , Li Zhang , Benjamin Odry