Related papers: Substrate Stiffness Changes Cell Rolling and Adhes…
Lubricated contacts in soft materials are important in various engineering systems and natural settings. Three major lubrication regimes are boundary (BL), mixed (ML), and elasto-hydrodynamic (EHL) lubrication, where the contact region is…
Adhesion-independent migration is a prominent mode of cell motility in confined environments, yet the physical principles that guide such movement remain incompletely understood. We present a phase-field model for simulating the motility of…
Surface stresses have recently emerged as a key player in the mechanics of highly compliant solids. The classic theories of contact mechanics describe adhesion with a compliant substrate as a competition between surface energies driving…
Biomolecules, such as proteins and RNAs, can phase separate in the cytoplasm of cells to form biomolecular condensates. Such condensates are liquid-like droplets that can wet biological surfaces such as membranes. Many molecules that…
The effect of random surface roughness on hydrodynamics of viscous incompressible liquid is discussed. Roughness-driven contributions to hydrodynamic flows, energy dissipation, and friction force are calculated in a wide range of…
We study the influence of surface roughness on the adhesion of elastic solids. Most real surfaces have roughness on many different length scales, and this fact is taken into account in our analysis. We consider in detail the case when the…
We investigate a continuum mechanical model for an adherent cell on two dimensional adhesive micropatterned substrates. The cell is modeled as an isotropic and homogeneous elastic material subject to uniform internal contractile stresses.…
The traditional approach in the study of hydrodynamic stability of stratified fluids includes the stick boundary conditions between layers. However, this rule may be violated in polymer systems and as a consequence various instabilities may…
We analyse the influence of a surface viscosity on the orientational dynamics of a nematic liquid crystal subjected to an oscillatory Couette flow. Approximate analytical solutions of nematohydrodynamic equations for small flow amplitudes…
The dynamics of a thin elastic sheet lubricated by a narrow layer of liquid is relevant to various situations and length scales. In the continuity of our previous work on viscous wakes, we study theoretically the effects of an external…
Crawling cell motility is vital to many biological processes such as wound healing and the immune response. Using a minimal model we investigate the effects of patterned substrate adhesiveness and biophysical cell parameters on the…
The conditions under which biological cells switch from a static to a motile state are fundamental to the understanding of many healthy and pathological processes. In this paper, we show that even in the presence of a fully symmetric…
Various adhesion mechanisms that have been understood in the field of synthetic adhesives are described and these are linked with situations relevant to fouling issues. The review mainly deals with mechanical aspects of adhesion phenomena,…
Optimal characterization of the mechanical properties of both cells and their surrounding is an issue of major interest. Indeed, cell function and development are strongly influenced by external stimuli. Furthermore, a change in cell…
A model system has been recently developed to study adhesion. It consists of a giant lipid bilayer vesicle with reconstituted lipo-polymers (repellers) as well as with lipo-ligands recognized by receptors covering the substrate. Adhesion in…
Near-field hydrodynamic interactions between bacteria and no-slip solid surfaces are the main mechanism underlying surface entrapment of bacteria. In this study, we employ a chiral two-body model to simulate bacterial dynamics near the…
Cells exhibit qualitatively different behaviors on substrates with different rigidities. The fact that cells are more polarized on the stiffer substrate motivates us to construct a two-dimensional cell with the distribution of focal…
The detachment dynamics of a fluid membrane with an isotropic spontaneous curvature from a flat substrate are studied by using meshless membrane simulations. The membrane is detached from an open edge leading to vesicle formation. With…
The one-dimensional crawling movement of a cell is considered in this theoretical study. Our active gel model shows that for a cell with weakly mechanosensitive adhesion complexes, as myosin contractility increases, a cell starts to move at…
Cooperative binding affects many processes in biology, but it is commonly addressed only in equilibrium. In this work we explore dynamical cooperativity in driven systems, where the cooperation occurs because some of the bonds change the…