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Static benchmarks measure a model frozen at training time. Real systems face distribution shift: new categories, paraphrased queries, drift: and must recover online via user corrections. No existing benchmark measures recovery speed under…

Machine Learning · Computer Science 2026-05-06 Adrian Grassi

Object-centric scene understanding is a fundamental challenge in computer vision. Existing approaches often rely on multi-stage pipelines that first apply pre-trained segmentors to extract individual objects, followed by per-object 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Yi Du , Yang You , Xiang Wan , Leonidas Guibas

Causal relationships among a set of variables are commonly represented by a directed acyclic graph. The orientations of some edges in the causal DAG can be discovered from observational/interventional data. Further edges can be oriented by…

Machine Learning · Computer Science 2022-05-30 Ramin Safaeian , Saber Salehkaleybar , Mahmoud Tabandeh

Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many…

Populations and Evolution · Quantitative Biology 2022-07-27 Brandon Legried , Sebastien Roch

Radio propagation modeling is essential in telecommunication research, as radio channels result from complex interactions with environmental objects. Recently, Machine Learning has been attracting attention as a potential alternative to…

With distributed machine learning being a prominent technique for large-scale machine learning tasks, communication complexity has become a major bottleneck for speeding up training and scaling up machine numbers. In this paper, we propose…

Machine Learning · Computer Science 2023-09-26 Pengyun Yue , Hanzhen Zhao , Cong Fang , Di He , Liwei Wang , Zhouchen Lin , Song-chun Zhu

A common problem in bioinformatics is related to identifying gene regulatory regions marked by relatively high frequencies of motifs, or deoxyribonucleic acid sequences that often code for transcription and enhancer proteins. Predicting…

Genomics · Quantitative Biology 2021-01-22 Ethan Jacob Moyer , Anup Das

Antibodies are versatile proteins that bind to pathogens like viruses and stimulate the adaptive immune system. The specificity of antibody binding is determined by complementarity-determining regions (CDRs) at the tips of these Y-shaped…

Biomolecules · Quantitative Biology 2022-01-31 Wengong Jin , Jeremy Wohlwend , Regina Barzilay , Tommi Jaakkola

This paper presents a new type of genetic algorithm for the set covering problem. It differs from previous evolutionary approaches first because it is an indirect algorithm, i.e. the actual solutions are found by an external decoder…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin

Evolutionary computation methods have been successfully applied to neural networks since two decades ago, while those methods cannot scale well to the modern deep neural networks due to the complicated architectures and large quantities of…

Neural and Evolutionary Computing · Computer Science 2019-03-12 Yanan Sun , Bing Xue , Mengjie Zhang , Gary G. Yen

Recent advancements in protein design have leveraged diffusion models to generate structural scaffolds, followed by a process known as protein inverse folding, which involves sequence inference on these scaffolds. However, these…

Biomolecules · Quantitative Biology 2025-02-27 Xingyi Zhang , Kun Xie , Ningqiao Huang , Wei Liu , Peilin Zhao , Sibo Wang , Kangfei Zhao , Biaobin Jiang

Entity type prediction is an important problem in knowledge graph (KG) research. A new KG entity type prediction method, named CORE (COmplex space Regression and Embedding), is proposed in this work. The proposed CORE method leverages the…

Machine Learning · Computer Science 2022-04-12 Xiou Ge , Yun-Cheng Wang , Bin Wang , C. -C. Jay Kuo

Objective. Natural language processing methods for medical auto-coding, or automatic generation of medical billing codes from electronic health records, generally assign each code independently of the others. They may thus assign codes for…

Computation and Language · Computer Science 2015-10-19 Michael Subotin , Anthony R. Davis

We propose a genetic algorithm powered evolution (GAPE) method to create deep learning solutions for energy and position estimation for reactor antineutrino interactions in the Precision Reactor Oscillation and Spectrum Experiment…

Locating the promoter region in DNA sequences is of paramount importance in the field of bioinformatics. This is a problem widely studied in the literature, however, not yet fully resolved. Some researchers have presented remarkable results…

Machine Learning · Computer Science 2021-12-08 Lauro Moraes , Pedro Silva , Eduardo Luz , Gladston Moreira

Protein function prediction is a crucial task in bioinformatics, with significant implications for understanding biological processes and disease mechanisms. While the relationship between sequence and function has been extensively…

Quantitative Methods · Quantitative Biology 2024-09-04 Shania Mitra , Lei Huang , Manolis Kellis

Computed Tomography (CT) is a key 3D imaging technology that fundamentally relies on the compute-intense back-projection operation to generate 3D volumes. GPUs are typically used for back-projection in production CT devices. However, with…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-28 Peng Chen , Mohamed Wahib , Xiao Wang , Shinichiro Takizawa , Takahiro Hirofuchi , Hirotaka Ogawa , Satoshi Matsuoka

Complexes of physically interacting proteins are one of the fundamental functional units responsible for driving key biological mechanisms within the cell. Their identification is therefore necessary not only to understand complex formation…

Computational Engineering, Finance, and Science · Computer Science 2012-11-27 Sriganesh Srihari , Hon Wai Leong

We address the task of higher-order derivative evaluation of computer programs that contain QR decompositions and real symmetric eigenvalue decompositions. The approach is a combination of univariate Taylor polynomial arithmetic and matrix…

Numerical Analysis · Mathematics 2010-10-01 Sebastian F. Walter , Lutz Lehmann , René Lamour

We present a numerical method for the reconstruction and optimization of complex field synthesis using coherent pulse combination systems. A genetic algorithm utilizing a Fourier optics based propagation method is developed for accurate…

Optics · Physics 2020-05-29 Randy Lemons , Sergio Carbajo