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A method based on mapping a symbolic sequence into a set of patterns (strings resulting from the sequence parsing) is proposed as a tool for the reconstruction of ancestral sequences. The set union of patterns comprises all the patterns…

Genomics · Quantitative Biology 2015-04-16 Bohdan Kozarzewski

Molecular sequence analysis is crucial for comprehending several biological processes, including protein-protein interactions, functional annotation, and disease classification. The large number of sequences and the inherently complicated…

Genomics · Quantitative Biology 2025-10-10 Sarwan Ali , Prakash Chourasia , Bipin Koirala , Murray Patterson

Gaussian Processes (GPs) are highly expressive, probabilistic models. A major limitation is their computational complexity. Naively, exact GP inference requires $\mathcal{O}(N^3)$ computations with $N$ denoting the number of modeled points.…

Machine Learning · Computer Science 2022-06-23 Gordian Edenhofer , Reimar H. Leike , Philipp Frank , Torsten A. Enßlin

We consider a generic representation problem of internal coordinates (bond lengths, valence angles, and dihedral angles) and their transformation to 3-dimensional Cartesian coordinates of a biomolecule. We show that the…

We propose a generic confidence-based approximation that can be plugged in and simplify the auto-regressive generation process with a proved convergence. We first assume that the priors of future samples can be generated in an independently…

Machine Learning · Computer Science 2019-10-16 YoungJoon Yoo , Sanghyuk Chun , Sangdoo Yun , Jung-Woo Ha , Jaejun Yoo

Replication of genetic material is an important process for all living organisms. Origins of replication initiate the copying of DNA at many points on a chromosome, and it is the distribution of these points that is relevant here, as it…

Quantitative Methods · Quantitative Biology 2025-10-16 Huw Day , N C Snaith

Localizing near-field sources considering practical arrays is a recent challenging topic for next generation wireless communication systems. Practical antenna array apertures with closely spaced elements exhibit direction-dependent mutual…

Recursive partitioning is the core of several statistical methods including CART, random forest, and boosted trees. Despite the popularity of tree based methods, to date, there did not exist methods for combining multiple trees into a…

Data Structures and Algorithms · Computer Science 2016-03-18 Sean Skwerer , Heping Zhang

Backpropagation is a classic automatic differentiation algorithm computing the gradient of functions specified by a certain class of simple, first-order programs, called computational graphs. It is a fundamental tool in several fields, most…

Logic in Computer Science · Computer Science 2019-11-07 Alois Brunel , Damiano Mazza , Michele Pagani

Coherent diffractive imaging (CDI), using both X-rays and electrons, has made extremely rapid progress over the past two decades. The associated reconstruction algorithms are typically iterative, and seeded with a crude first estimate. A…

Image and Video Processing · Electrical Eng. & Systems 2019-06-25 Konstantin M. Pavlov , Kaye S. Morgan , Vasily I. Punegov , David M. Paganin

An approach based on using the idea of distinguished coding phase in explicit form for identification of protein-coding regions (exons) in whole genome has been proposed. For several genomes an optimal window length for averaging GC-content…

Biological Physics · Physics 2007-05-23 Alexander N. Gorban , Andrey Yu. Zinovyev , Tatyana G. Popova

Recent advancements have been made in the development of cell-based in-vitro neuronal networks, or organoids. In order to better understand the network structure of these organoids, a super-selective algorithm has been proposed for…

In this paper, we present an optical computing method for string data alignment applicable to genome information analysis. By applying moire technique to spatial encoding patterns of deoxyribonucleic acid (DNA) sequences, association…

In many real-world prediction tasks, class labels include information about the relative ordering between labels, which is not captured by commonly-used loss functions such as multi-category cross-entropy. Recently, the deep learning…

Machine Learning · Computer Science 2020-11-16 Wenzhi Cao , Vahid Mirjalili , Sebastian Raschka

Image ordinal estimation is to predict the ordinal label of a given image, which can be categorized as an ordinal regression problem. Recent methods formulate an ordinal regression problem as a series of binary classification problems. Such…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Haiping Zhu , Hongming Shan , Yuheng Zhang , Lingfu Che , Xiaoyang Xu , Junping Zhang , Jianbo Shi , Fei-Yue Wang

Learning directed acyclic graph (DAG) that describes the causality of observed data is a very challenging but important task. Due to the limited quantity and quality of observed data, and non-identifiability of causal graph, it is almost…

Machine Learning · Computer Science 2022-11-23 Dezhi Yang , Guoxian Yu , Jun Wang , Zhengtian Wu , Maozu Guo

Predictive coding networks (PCNs) are an influential model for information processing in the brain. They have appealing theoretical interpretations and offer a single mechanism that accounts for diverse perceptual phenomena of the brain. On…

Machine Learning · Computer Science 2021-03-08 Tommaso Salvatori , Yuhang Song , Thomas Lukasiewicz , Rafal Bogacz , Zhenghua Xu

We propose a novel end-to-end method for cross-view pose estimation. Given a ground-level query image and an aerial image that covers the query's local neighborhood, the 3 Degrees-of-Freedom camera pose of the query is estimated by matching…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Zimin Xia , Olaf Booij , Julian F. P. Kooij

Digital image correlation (DIC) is a widely used optical metrology for quantitative deformation measurement due to its non-contact, low-cost, highly precise feature. DIC relies on nonlinear optimization algorithm. Thus it is quite important…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Peihan Tu

Motivation: Molecular interaction networks summarize complex biological processes as graphs, whose structure is informative of biological function at multiple scales. Simultaneously, omics technologies measure the variation or activity of…

Quantitative Methods · Quantitative Biology 2020-12-24 Ramin Hasibi , Tom Michoel
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