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DNA sequencing is the process of determining the exact order of the nucleotide bases of an individual's genome in order to catalogue sequence variation and understand its biological implications. Whole-genome sequencing techniques produce…

Data Structures and Algorithms · Computer Science 2015-09-18 Ljiljana Brankovic , Costas S. Iliopoulos , Ritu Kundu , Manal Mohamed , Solon P. Pissis , Fatima Vayani

In this paper, we propose the Neural Knowledge DNA, a framework that tailors the ideas underlying the success of neural networks to the scope of knowledge representation. Knowledge representation is a fundamental field that dedicate to…

Artificial Intelligence · Computer Science 2016-03-01 Haoxi Zhang , Cesar Sanin , Edward Szczerbicki

The human genome contains repetitive DNA at different level of sequence length, number and dispersion. Highly repetitive DNA is particularly rich in homo-- and di--nucleotide repeats, while middle repetitive DNA is rich of families of…

Genomics · Quantitative Biology 2009-11-11 Francesco Piazza , Pietro Lio

An RNA sequence is a word over an alphabet on four elements $\{A,C,G,U\}$ called bases. RNA sequences fold into secondary structures where some bases match one another while others remain unpaired. Pseudoknot-free secondary structures can…

Data Structures and Algorithms · Computer Science 2018-03-28 Édouard Bonnet , Paweł Rzążewski , Florian Sikora

The conception of multi-alphabetical genetics is represented. Matrix forms of the representation of the multi-level system of molecular-genetic alphabets have revealed algebraic properties of this system. These properties are connected with…

Other Quantitative Biology · Quantitative Biology 2013-01-18 Sergey V. Petoukhov

This paper makes a number of connections between life and various facets of genetic and evolutionary algorithms research. Specifically, it addresses the topics of adaptation, multiobjective optimization, decision making, deception, and…

Neural and Evolutionary Computing · Computer Science 2016-08-31 Fernando G. Lobo

This work proposes a markovian memoryless model for the DNA that simplifies enormously the complexity of it. We encode nucleotide sequences into symbolic sequences, called words, from which we establish meaningful length of words and group…

Biological Physics · Physics 2015-10-09 Shambhavi Srivastava , Murilo S. Baptista

Neural codes appear efficient. Naturally, neuroscientists contend that an efficient process is responsible for generating efficient codes. They argue that natural selection is the efficient process that generates those codes. Although…

Neurons and Cognition · Quantitative Biology 2022-03-21 Han Kim

A new family of compound Poisson distribution functions from statistical linguistic is used to study the n-tuples and nucleotide composition features of DNA sequences. The relative frequency distribution of the 6-tuples and 7- tuples…

Statistical Mechanics · Physics 2007-05-23 K. L. Ng , S. P. Li

In many situations, the gene expression signature is a unique marker of the biological state. We study the modification of the gene expression distribution function when the biological state of a system experiences a change. This change may…

Quantitative Methods · Quantitative Biology 2022-05-19 Augusto Gonzalez , Joan Nieves , Maria Luisa Bringas Vega , Pedro Valdes Sosa

A fundamental design rule that nature has developed for biological machines is the intimate correlation between motion and function. One class of biological machines is molecular motors in living cells, which directly convert chemical…

Biological Physics · Physics 2021-05-11 Na Liu

In a certain way, this paper presents the continuation of the previous one which discussed the harmonic structure of the genetic code (Rakocevic, 2004). Several new harmonic structures presented in this paper, through specific unity and…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Miloje M. Rakocevic

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

The continuity of life and its evolution, we proposed, emerge from an interactive group process manifested in networks of interaction. We term this process \textit{survival-of-the-fitted}. Here, we reason that survival of the fitted results…

Neural and Evolutionary Computing · Computer Science 2025-06-17 Irun R. Cohen , Assaf Marron

The genetic code is profoundly shaped by an origin in ancient RNA-mediated interactions, needing an extended development to reach the Standard Genetic Code (SGC). That development can serially use RNA specificities, a ribonucleopeptide…

Populations and Evolution · Quantitative Biology 2024-06-13 Michael Yarus

The genetic code is the set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins (amino acid sequences) by living cells. The code defines a mapping between tri-nucleotide sequences,…

Other Quantitative Biology · Quantitative Biology 2015-12-03 Jayanta Kumar Das , Atrayee Majumder , Pabitra Pal Choudhury

A new version of DNA walks, where nucleotides are regarded unequal in their contribution to a walk is introduced, which allows us to study thoroughly the "fine structure" of nucleotide sequences. The approach is based on the assumption that…

Genomics · Quantitative Biology 2007-05-23 Diana Duplij , Steven Duplij

We apply the theory of learning to physically renormalizable systems in an attempt to develop a theory of biological evolution, including the origin of life, as multilevel learning. We formulate seven fundamental principles of evolution…

Populations and Evolution · Quantitative Biology 2022-10-12 Vitaly Vanchurin , Yuri I. Wolf , Mikhail I. Katsnelson , Eugene V. Koonin

In this paper we investigate a neural network model in which weights between computational nodes are modified according to a local learning rule. To determine whether local learning rules are sufficient for learning, we encode the network…

Neural and Evolutionary Computing · Computer Science 2025-12-08 Jonathan Baxter

The structure of the genetic code is discussed in formal terms. A rectangular table of the code ("the code matrix"), whose properties reveal its arithmetical content tagged with the information symbols in several notations. New parameters…

Other Quantitative Biology · Quantitative Biology 2009-07-22 Felix Filatov
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