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The evolution in coding DNA sequences brings new flexibility and freedom to the codon words, even as the underlying nucleotides get significantly ordered. These curious contra-rules of gene organisation are observed from the distribution of…

Biological Physics · Physics 2007-05-23 Sujay Chattopadhyay , William A. Kanner , Jayprokas Chakrabarti

We show that textual analysis of microbial genomes reveal telling footprints of the early evolution of the genomes. The frequencies of word occurrence of random DNA sequences considered as texts in their four nucleotides are expected to…

Biological Physics · Physics 2007-05-23 Li-Ching Hsieh , Liaofu Luo , HC Lee

This paper presents a probabilistic approach for DNA sequence analysis. A DNA sequence consists of an arrangement of the four nucleotides A, C, T and G and different representation schemes are presented according to a probability measure…

Quantitative Methods · Quantitative Biology 2010-02-12 Amrita Priyam , B. M. Karan , G. Sahoo

Language models, especially transformer-based ones, have achieved colossal success in NLP. To be precise, studies like BERT for NLU and works like GPT-3 for NLG are very important. If we consider DNA sequences as a text written with an…

Genomics · Quantitative Biology 2026-01-21 Musa Nuri Ihtiyar , Arzucan Ozgur

We have presented the basic knowledge on the structure of molecules coding the genetic information, mechanisms of transfer of this information from DNA to proteins and phenomena connected with replication of DNA. In particular, we have…

Genomics · Quantitative Biology 2009-09-30 Dorota Mackiewicz , Stanislaw Cebrat

Replication of DNA and synthesis of proteins are studied from the view-point of quantum database search. Identification of a base-pairing with a quantum query gives a natural (and first ever) explanation of why living organisms have 4…

Quantum Physics · Physics 2009-11-06 Apoorva Patel

Evolution of genetic code is studied as the change in the choice of enzymes that are used to synthesize amino acids from the genetic information of nucleic acids. We propose the following theory: the differentiation of physiological states…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 H. Takagi , K. Kaneko , T. Yomo

The rules that specify how the information contained in DNA codes amino acids, is called "the genetic code". Using a simplified version of the Penna nodel, we are using computer simulations to investigate the importance of the genetic code…

Genomics · Quantitative Biology 2009-11-10 E. Gultepe , M. L. Kurnaz

The genetic code structure into distinct multiplet-classes as well as the numeric degeneracies of the latter are revealed by a two-step process. First, an empirical inventory of the degeneracies (of the shuffled multiplets) in two specific…

Other Quantitative Biology · Quantitative Biology 2009-11-13 Tidjani Negadi

A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards…

Biomolecules · Quantitative Biology 2008-05-06 Denis A. Semenov

A nucleotides sequence is identified, in the two (four) letters alphabet, by the the labels of a vector state of an irreducible representation of U_q(sl(2)) (U_q(sl(2) + sl(2))), in the limit q -> 0. A master equation for the distribution…

Biomolecules · Quantitative Biology 2007-05-23 C. Minichini , A. Sciarrino

Living organisms are not just random collections of organic molecules. There is continuous information processing going on in the apparent bouncing around of molecules of life. Optimisation criteria in this information processing can be…

Quantum Physics · Physics 2007-05-23 Apoorva Patel

Tandem duplication is an evolutionary process whereby a segment of DNA is replicated and proximally inserted. The different configurations that can arise from this process give rise to some interesting combinatorial questions. Firstly, we…

Combinatorics · Mathematics 2016-11-25 L Penso-Dolfin , CD Greenman

A representation of the genetic code as a six-dimensional Boolean hypercube is proposed. It is assumed here that this structure is the result of the hierarchical order of the interaction energies of the bases in codon-anticodon recognition.…

Soft Condensed Matter · Physics 2007-05-23 Miguel A. Jimenez-Montano , Carlos R. de la Mora-Basanez , Thorsten Poeschel

Complex systems, such as life and languages, are governed by principles of evolution. The analogy and comparison between biology and linguistics\cite{alphafold2, RoseTTAFold, lang_virus, cell language, faculty1, language of gene, Protein…

Populations and Evolution · Quantitative Biology 2026-03-18 Li-Min Wang , Hsing-Yi Lai , Sun-Ting Tsai , Chen Siang Ng , Kevin Sheng-Kai Ma , Shan-Jyun Wu , Meng-Xue Tsai , Yi-Ching Su , Daw-Wei Wang , Tzay-Ming Hong

This paper concentrates on relationships of formal systems with biology. The paper is based on previous papers by the author. We have freely used texts of those papers where the formulations are of use, and we have extended the concepts and…

History and Philosophy of Physics · Physics 2015-12-15 Louis H. Kauffman

Much information is stored in amino acid composition of protein and base composition of DNA. We simulated the evolution of amino acid frequencies and genomic GC content by a linguistic model. It is showed that the evolution of genetic code…

Genomics · Quantitative Biology 2007-05-23 Dirson Jian Li

Much evolutionary information is stored in the fluctuations of protein length distributions. The genome size and non-coding DNA content can be calculated based only on the protein length distributions. So there is intrinsic relationship…

Genomics · Quantitative Biology 2008-06-03 Dirson Jian Li , Shengli Zhang

The yearly global production of data is growing exponentially, outpacing the capacity of existing storage media, such as tape and disk, and surpassing our ability to store it. DNA storage - the representation of arbitrary information as…

Quantitative Methods · Quantitative Biology 2023-10-04 Thomas Heinis , Roman Sokolovskii , Jamie J. Alnasir

All living organisms use the same genetic languages in their molecular biology machinery. They can be understood as the optimal solutions to the replication tasks involving DNA and proteins. These solutions perfectly fit the pattern…

Other Quantitative Biology · Quantitative Biology 2025-05-21 Apoorva D. Patel
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