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Related papers: Graph Residual Flow for Molecular Graph Generation

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Designing molecules with specific properties is a long-lasting research problem and is central to advancing crucial domains such as drug discovery and material science. Recent advances in deep graph generative models treat molecule design…

Machine Learning · Computer Science 2022-03-02 Yuanqi Du , Xiaojie Guo , Amarda Shehu , Liang Zhao

Recent advances in graph learning have paved the way for innovative retrieval-augmented generation (RAG) systems that leverage the inherent relational structures in graph data. However, many existing approaches suffer from rigid, fixed…

Information Retrieval · Computer Science 2025-03-26 Yuan Li , Jun Hu , Jiaxin Jiang , Zemin Liu , Bryan Hooi , Bingsheng He

The task of deducing three-dimensional molecular configurations from their two-dimensional graph representations holds paramount importance in the fields of computational chemistry and pharmaceutical development. The rapid advancement of…

Biomolecules · Quantitative Biology 2025-01-09 Bobin Yang , Jie Deng , Zhenghan Chen , Ruoxue Wu

In the realm of generative models for graphs, extensive research has been conducted. However, most existing methods struggle with large graphs due to the complexity of representing the entire joint distribution across all node pairs and…

Social and Information Networks · Computer Science 2024-05-15 Andreas Bergmeister , Karolis Martinkus , Nathanaël Perraudin , Roger Wattenhofer

Graph-structured data jointly contain discrete topology and continuous geometry, which poses fundamental challenges for generative modeling due to heterogeneous distributions, incompatible noise dynamics, and the need for equivariant…

Machine Learning · Computer Science 2026-04-10 Rongjian Xu , Teng Pang , Zhiqiang Dong , Guoqiang Wu

Despite the success of foundation models in language and vision, molecular graph generation still lacks a unified framework for heterogeneous design tasks with reliable controllability. While reinforcement learning (RL) offers a natural…

Machine Learning · Computer Science 2026-05-18 Yihan Zhu , Yuhan Liu , Weijiang Li , Tengfei Luo , Meng Jiang

Graph neural networks (GNNs), which are capable of learning representations from graphical data, are naturally suitable for modeling molecular systems. This review introduces GNNs and their various applications for small organic molecules.…

Machine Learning · Computer Science 2023-10-10 Yuyang Wang , Zijie Li , Amir Barati Farimani

Graph generation is a fundamental task with wide applications in modeling complex systems. Although existing methods align the spectrum or degree profile of the target graph, they often ignore the geometry induced by eigenvectors and the…

Machine Learning · Computer Science 2025-10-06 Xikun Huang , Tianyu Ruan , Chihao Zhang , Shihua Zhang

Computational fluid dynamics (CFD) provides high-fidelity simulations of fluid flows but remains computationally expensive for many-query applications. In recent years deep learning (DL) has been used to construct data-driven fluid-dynamic…

Machine Learning · Computer Science 2026-04-13 David Ramos , Lucas Lacasa , Fermín Gutiérrez , Eusebio Valero , Gonzalo Rubio

A common objective in the analysis of tabular data is estimating the conditional distribution (in contrast to only producing predictions) of a set of "outcome" variables given a set of "covariates", which is sometimes referred to as the…

Machine Learning · Statistics 2024-10-08 Zhuoqun Wang , Naoki Awaya , Li Ma

We present the Graph Forward-Forward (GFF) algorithm, an extension of the Forward-Forward procedure to graphs, able to handle features distributed over a graph's nodes. This allows training graph neural networks with forward passes only,…

Machine Learning · Computer Science 2023-02-13 Daniele Paliotta , Mathieu Alain , Bálint Máté , François Fleuret

Generative flows are attractive because they admit exact likelihood optimization and efficient image synthesis. Recently, Kingma & Dhariwal (2018) demonstrated with Glow that generative flows are capable of generating high quality images.…

Machine Learning · Computer Science 2019-05-21 Emiel Hoogeboom , Rianne van den Berg , Max Welling

Urban wind flow modeling and simulation play an important role in air quality assessment and sustainable city planning. A key challenge for modeling and simulation is handling the complex geometries of the urban landscape. Low order models…

Machine Learning · Computer Science 2025-12-18 Francisco Giral , Álvaro Manzano , Ignacio Gómez , Petros Koumoutsakos , Soledad Le Clainche

Localizing the source of graph diffusion phenomena, such as misinformation propagation, is an important yet extremely challenging task. Existing source localization models typically are heavily dependent on the hand-crafted rules.…

Social and Information Networks · Computer Science 2022-06-22 Junxiang Wang , Junji Jiang , Liang Zhao

Generative modeling is typically framed as learning mapping rules, but from an observer's perspective without access to these rules, the task becomes disentangling the geometric support from the probability distribution. We propose that…

Machine Learning · Statistics 2025-12-04 Rui Tong

The recently proposed generative flow networks (GFlowNets) are a method of training a policy to sample compositional discrete objects with probabilities proportional to a given reward via a sequence of actions. GFlowNets exploit the…

Machine Learning · Computer Science 2024-02-27 Daniil Tiapkin , Nikita Morozov , Alexey Naumov , Dmitry Vetrov

This work provides a comprehensive derivation of the parameter gradients for GATv2 [4], a widely used implementation of Graph Attention Networks (GATs). GATs have proven to be powerful frameworks for processing graph-structured data and,…

Machine Learning · Computer Science 2023-04-24 Marion Neumeier , Andreas Tollkühn , Sebastian Dorn , Michael Botsch , Wolfgang Utschick

Inspired by the success of foundation models in applications such as ChatGPT, as graph data has been ubiquitous, one can envision the far-reaching impacts that can be brought by Graph Foundation Models (GFMs) with broader applications in…

Machine Learning · Computer Science 2024-11-12 Zehong Wang , Zheyuan Zhang , Nitesh V Chawla , Chuxu Zhang , Yanfang Ye

Modern continuous-time generative models typically induce \emph{V-shaped} flows: each sample travels independently along a nearly straight trajectory from the prior to the data. Although effective, this independent movement overlooks the…

Machine Learning · Computer Science 2026-02-05 Arip Asadulaev , Semyon Semenov , Abduragim Shtanchaev , Eric Moulines , Fakhri Karray , Martin Takac

Modeling molecular potential energy surface is of pivotal importance in science. Graph Neural Networks have shown great success in this field. However, their message passing schemes need special designs to capture geometric information and…

Machine Learning · Computer Science 2023-04-24 Xiyuan Wang , Muhan Zhang
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