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Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…

Machine Learning · Statistics 2016-08-17 Joseph Futoma , Mark Sendak , C. Blake Cameron , Katherine Heller

Knee osteoarthritis (KOA) is a degenerative joint disease that can lead to chronic pain, reduced mobility, and long-term disability. Automated severity grading from knee radiographs can support early assessment, but current methods heavily…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Chandravardhan Singh Raghaw , Anushka Parwal , Shahid Shafi Dar , Prajakta Darade , Nagendra Kumar

Machine learning (ML) is increasingly used to support decision-making in the healthcare sector. While ML approaches provide promising results with regard to their classification performance, most share a central limitation, namely their…

This paper studies the problem of learning diagnostic policies from training examples. A diagnostic policy is a complete description of the decision-making actions of a diagnostician (i.e., tests followed by a diagnostic decision) for all…

Artificial Intelligence · Computer Science 2011-09-13 V. Bayer-Zubek , T. G. Dietterich

Period-prevalent cohorts are often used for their cost-saving potential in epidemiological studies of survival outcomes. Under this design, prevalent patients allow for evaluations of long-term survival outcomes without the need for long…

Methodology · Statistics 2024-10-28 Nicholas Hartman

In this study, the reliability of identified risk factors associated with osteoporosis is investigated using a new clustering-based method on electronic medical records. This study proposes utilizing a new CLustering Iterations Framework…

Machine Learning · Computer Science 2024-05-28 Mikayla Calitis

Deep learning fostered a leap ahead in automated skin lesion analysis in the last two years. Those models are expensive to train and difficult to parameterize. Objective: We investigate methodological issues for designing and evaluating…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Eduardo Valle , Michel Fornaciali , Afonso Menegola , Julia Tavares , Flávia Vasques Bittencourt , Lin Tzy Li , Sandra Avila

Determining the type of kidney stones allows urologists to prescribe a treatment to avoid recurrence of renal lithiasis. An automated in-vivo image-based classification method would be an important step towards an immediate identification…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Francisco Lopez-Tiro , Vincent Estrade , Jacques Hubert , Daniel Flores-Araiza , Miguel Gonzalez-Mendoza , Gilberto Ochoa-Ruiz , Christian Daul

Amyotrophic Lateral Sclerosis (ALS) is characterized as a rapidly progressive neurodegenerative disease that presents individuals with limited treatment options in the realm of medical interventions and therapies. The disease showcases a…

Machine Learning · Computer Science 2024-07-12 Ritesh Mehta , Aleksandar Pramov , Shashank Verma

We propose a Bayesian model selection approach that allows medical practitioners to select among predictor variables while taking their respective costs into account. Medical procedures almost always incur costs in time and/or money. These…

Methodology · Statistics 2024-05-07 Erica M. Porter , Christopher T. Franck , Stephen Adams

Clinical methods that assess gait in Parkinson's Disease (PD) are mostly qualitative. Quantitative methods necessitate costly instrumentation or cumbersome wearable devices, which limits their usability. Only few of these methods can…

Machine Learning · Computer Science 2020-06-23 Nabeel Seedat , Vered Aharonson

The accuracy of coronary artery disease (CAD) diagnosis is dependent on a variety of factors, including demographic, symptom, and medical examination, ECG, and echocardiography data, among others. In this context, artificial intelligence…

Artificial Intelligence · Computer Science 2023-08-30 Elham Nasarian , Danial Sharifrazi , Saman Mohsenirad , Kwok Tsui , Roohallah Alizadehsani

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

learning algorithms. In this paper, we review the classification algorithms used in the health care system (chronic diseases) and present the neural network-based Ensemble learning method. We briefly describe the commonly used algorithms…

Machine Learning · Computer Science 2021-03-16 Jafar Abdollahi , Babak Nouri-Moghaddam , Mehdi Ghazanfari

The morphological changes in knee cartilage (especially femoral and tibial cartilages) are closely related to the progression of knee osteoarthritis, which is expressed by magnetic resonance (MR) images and assessed on the cartilage…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Dong Liang , Jun Liu , Kuanquan Wang , Gongning Luo , Wei Wang , Shuo Li

Objectives: We aim to quantify longitudinal acute kidney injury (AKI) trajectories and to describe transitions through progressing and recovery states and outcomes among hospitalized patients using multistate models. Methods: In this large,…

Quantitative Methods · Quantitative Biology 2023-03-13 Esra Adiyeke , Yuanfang Ren , Ziyuan Guan , Matthew M. Ruppert , Parisa Rashidi , Azra Bihorac , Tezcan Ozrazgat-Baslanti

Literature on machine learning for multiple sclerosis has primarily focused on the use of neuroimaging data such as magnetic resonance imaging and clinical laboratory tests for disease identification. However, studies have shown that these…

Kidneys are the filter of the human body. About 10% of the global population is thought to be affected by Chronic Kidney Disease (CKD), which causes kidney function to decline. To protect in danger patients from additional kidney damage,…

As artificial intelligence systems move toward clinical deployment, ensuring reliable prediction behavior is fundamental for safety-critical decision-making tasks. One proposed safeguard is selective prediction, where models can defer…

Machine Learning · Computer Science 2026-05-25 L. Julián Lechuga López , Farah E. Shamout , Tim G. J. Rudner

Chronic diseases, such as cardiovascular disease, diabetes, chronic kidney disease, and thyroid disorders, are the leading causes of premature mortality worldwide. Early detection and intervention are crucial for improving patient outcomes,…

Machine Learning · Computer Science 2025-11-04 Houda Belhad , Asmae Bourbia , Salma Boughanja
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