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The radiation (reaction, Robin) boundary condition for the continuum diffusion equation is widely used in chemical and biological applications to express reactive boundaries. The underlying trajectories of the diffusing particles are…

Mathematical Physics · Physics 2007-09-02 A. Singer , Z. Schuss , D. Holcman

Motivated by models of signaling pathways in B lymphocytes, which have extremely large nuclei, we study the question of how reaction-diffusion equations in thin $2D$ domains may be approximated by diffusion equations in regions of smaller…

Analysis of PDEs · Mathematics 2020-07-17 Adam Bobrowski

An explicit output-feedback boundary feedback law is introduced that stabilizes an unstable linear constant-coefficient reaction-diffusion equation on an $n$-ball (which in 2-D reduces to a disk and in 3-D reduces to a sphere) using only…

Optimization and Control · Mathematics 2015-11-23 Rafael Vazquez , Miroslav Krstic

In recent letter [Phys. Rev. Lett {\bf 105}, 150606 (2010)], the surface-mediated diffusion problem is theoretically discussed, and interesting results have been obtained. However, for more general cases, the ansatz of solutions of the…

Mathematical Physics · Physics 2015-03-06 Yunxin Zhang

We revise the encounter-based approach to imperfect diffusion-controlled reactions, which employs the statistics of encounters between a diffusing particle and the reactive region to implement surface reactions. We extend this approach to…

Statistical Mechanics · Physics 2023-10-03 Denis S. Grebenkov

We study the dynamics of simple reactions where the chemical species are confined on a general, time-modulated surface, and subjected to externally-imposed stirring. The study of these inhomogeneous effects requires a model based on a…

Fluid Dynamics · Physics 2009-02-25 Khalid Kamhawi , Lennon Ó Náraigh

We consider a random diffusion dynamics for an infinite system of hard spheres of two different sizes evolving in $\mathbb{R}^d$, its reversible probability measure, and its projection on the subset of the large spheres. The main feature is…

Probability · Mathematics 2024-03-05 Myriam Fradon , Julian Kern , Sylvie Roelly , Alexander Zass

The use of fully or partially absorbing boundary conditions for diffusion-based problems has become paradigmatic in physical chemistry and biochemistry to describe reactions occurring in solutions or in living media. However, as chemical…

Statistical Mechanics · Physics 2022-12-13 Francesco Piazza

We develop an encounter-based approach for describing restricted diffusion with a gradient drift towards a partially reactive boundary. For this purpose, we introduce an extension of the Dirichlet-to-Neumann operator and use its eigenbasis…

Chemical Physics · Physics 2022-10-10 Denis S. Grebenkov

In this paper we perform a formal asymptotic analysis on a kinetic model for reactive mixtures in order to derive a reaction-diffusion system of Maxwell-Stefan type. More specifically, we start from the kinetic model of simple reacting…

Fluid Dynamics · Physics 2019-11-20 Benjamin Anwasia , Patrícia Gonçalves , Ana Jacinta Soares

How many times a diffusing molecule can permeate across a membrane or be adsorbed on a substrate? We employ the encounter-based approach to find the statistics of adsorption or permeation events for molecular diffusion in a general…

Chemical Physics · Physics 2025-07-15 Denis S. Grebenkov

The derivation of suitable analytical models is an important step for the design and analysis of molecular communication systems. However, many existing models have limited applicability in practical scenarios due to various simplifications…

Emerging Technologies · Computer Science 2019-11-28 Maximilian Schäfer , Wayan Wicke , Werner Haselmayr , Rudolf Rabenstein , Robert Schober

Bimolecular binding rate constants are often used to describe the association of large molecules, such as proteins. In this paper, we analyze a model for such binding rates that includes the fact that pairs of molecules can bind only in…

Analysis of PDEs · Mathematics 2020-11-05 Claire E. Plunkett , Sean D. Lawley

We consider a reaction-diffusion system for two densities lying in adjacent domains of $\mathbb{R}^N$. We treat two configurations: either a cylinder and its complement, or two half-spaces. Diffusion and reaction heterogeneities for the two…

Analysis of PDEs · Mathematics 2025-06-06 Henri Berestycki , Luca Rossi , Andrea Tellini

We present an exact calculation of the mean first-passage time to a target on the surface of a 2D or 3D spherical domain, for a molecule alternating phases of surface diffusion on the domain boundary and phases of bulk diffusion. The…

Statistical Mechanics · Physics 2015-05-27 O. Bénichou , D. S. Grebenkov , P. E. Levitz , C. Loverdo , R. Voituriez

Biomolecules, such as proteins and RNAs, can phase separate in the cytoplasm of cells to form biomolecular condensates. Such condensates are liquid-like droplets that can wet biological surfaces such as membranes. Many molecules that…

Soft Condensed Matter · Physics 2024-09-04 Xueping Zhao , Susanne Liese , Alf Honigmann , Frank Jülicher , Christoph A. Weber

We study long-time properties of reversible reaction-diffusion systems of type A + B <-> C by means of perturbation expansion in powers of 1/t (inverse of time). For the case of equal diffusion coefficients we present exact formulas for the…

Statistical Mechanics · Physics 2009-11-07 Zbigniew Koza

In this paper we present a mathematical study of particle diffusion inside and outside a spherical biological cell that has been exposed on one side to a propagating planar diffusive front. The media inside and outside the spherical cell…

Biological Physics · Physics 2024-06-11 Sandeep Santhosh Kumar , Stanley J. Miklavcic

In this paper we consider the diffusion of nanoparticles taken up by a semi-permeable spherical cell placed in the path of a diffusive particle field generated by an external planar source. The cell interior and exterior are characterized…

Biological Physics · Physics 2024-06-11 Stanley J. Miklavcic

The kinetic processes in nanoparticle-based catalysis are dominated by large fluctuations and spatiotemporal heterogeneities, in particular for diffusion-influenced reactions which are far from equilibrium. Here, we report results from…

Chemical Physics · Physics 2020-11-03 Yi-Chen Lin , Won Kyu Kim , Joachim Dzubiella