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Small animal Positron Emission Tomography (PET) is dedicated to small animal imaging. Animals used in experiments, such as rats and monkeys, are often much smaller than human bodies, which requires higher position and energy precision of…
A PET scanner based on silicon photomultipliers (SiPMs) has been widely used as an advanced nuclear medicine imaging technique that yields quantitative images of regional in vivo biology and biochemistry. The compact size of the SiPM allows…
Position Emission Tomography (PET) is an advanced clinical diagnostic imaging technique for nuclear medicine. Small animal PET is increasingly uesd for studying the animal model of disease, new drugs and new therapies. A prototype of…
The aim of this study is to design and evaluate a simple free running Analog-Digital Converter (ADC) based on the Field Programmable Gate Array (FPGA) device to accomplish the energy and position readout of the silicon photomultiplier…
Modern PET scanners based on scintillating crystals use solid state photo detectors for light readout. The small area of these devices is beneficial for spatial resolution, but also leads to a large number of electronic channels to be read…
Objective. This study investigates the best achievable performance of a brain-dedicated PET system with high resolution and sensitivity by evaluating different detector configurations, while maintaining a practical system design suitable…
Fault detection and diagnosis is critical to many applications in order to ensure proper operation and performance over time. Positron emission tomography (PET) systems that require regular calibrations by qualified scanner operators are…
This paper describes the characterization of crystal matrices and silicon photomultiplier arrays for a novel Positron Emission Tomography (PET) detector, namely the external plate of the EndoTOFPET-US system. The EndoTOFPET-US collaboration…
Hyperion-IID is a positron emission tomography (PET) insert which allows simultaneous operation in a clinical magnetic resonance imaging (MRI) scanner. To read out the scintillation light of the employed LYSO crystal arrays with a pitch of…
A novel approach to tomographic data processing has been developed and evaluated using the Jagiellonian PET (J-PET) scanner as an example. We propose a system in which there is no need for powerful, local to the scanner processing facility,…
Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…
Positron Emission Tomography (PET) enables functional imaging of deep brain structures, but the bulk and weight of current systems preclude their use during many natural human activities, such as locomotion. The proposed long-term solution…
Miniaturized calcium imaging is an emerging neural recording technique that has been widely used for monitoring neural activity on a large scale at a specific brain region of rats or mice. Most existing calcium-image analysis pipelines…
Organ-specific, targeted Field-of-View (FoV) Positron Emission Tomography (PET)/Magnetic Resonance Imaging (MRI) inserts are viable solutions for a number of imaging tasks where whole-body PET/MRI systems lack the necessary sensitivity and…
Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) automatic 3-D registration is implemented and validated for small animal image volumes so that the high-resolution anatomical MRI information can be fused with the low…
Fully Field Programmable Gate Array (FPGA)based digitizer for high-resolution time and energy measurement is an attractive low cost solution for the readout electronics in positron emission computed tomography (PET)detector. In recent…
Positron Emission Tomography (PET) enables functional imaging of deep brain structures, but the bulk and weight of current systems preclude their use during many natural human activities, such as locomotion. The proposed long-term solution…
Studies of the human brain during natural activities, such as locomotion, would benefit from the ability to image deep brain structures during these activities. While Positron Emission Tomography (PET) can image these structures, the bulk…
Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…
Images from Positron Emission Tomography (PET) deliver functional data such as perfusion and metabolism. On the other hand, images from Magnetic Resonance Imaging (MRI) provide information describing anatomical structures. Fusing the…