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Recent advances in experimental techniques enable the simultaneous recording of activity from thousands of neurons in the brain, presenting both an opportunity and a challenge: to build meaningful, scalable models of large neural…

Biological Physics · Physics 2025-08-05 Luca Di Carlo , Francesca Mignacco , Christopher W. Lynn , William Bialek

Perceptions and actions, thoughts and memories result from coordinated activity in hundreds or even thousands of neurons in the brain. It is an old dream of the physics community to provide a statistical mechanics description for these and…

Disordered Systems and Neural Networks · Physics 2024-09-04 Leenoy Meshulam , William Bialek

Models of complex networks often incorporate node-intrinsic properties abstracted as hidden variables. The probability of connections in the network is then a function of these variables. Real-world networks evolve over time, and many…

Physics and Society · Physics 2021-05-19 Harrison Hartle , Fragkiskos Papadopoulos , Dmitri Krioukov

Effective analysis in neuroscience benefits significantly from robust conceptual frameworks. Traditional metrics of interbrain synchrony in social neuroscience typically depend on fixed, correlation-based approaches, restricting their…

Neurons and Cognition · Quantitative Biology 2025-12-01 Nicolás Hinrichs , Noah Guzmán , Melanie Weber

Dynamic network models (DNMs) are belief networks for temporal reasoning. The DNM methodology combines techniques from time series analysis and probabilistic reasoning to provide (1) a knowledge representation that integrates…

Artificial Intelligence · Computer Science 2013-03-08 Paul Dagum , Adam Galper

Maximum entropy methods provide a principled path connecting measurements of neural activity directly to statistical physics models, and this approach has been successful for populations of $N\sim 100$ neurons. As $N$ increases in new…

Biological Physics · Physics 2023-10-18 Christopher W. Lynn , Qiwei Yu , Rich Pang , William Bialek , Stephanie E. Palmer

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

Neurons and Cognition · Quantitative Biology 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

Diagnosing epilepsy requires accurate seizure detection and classification, but traditional manual EEG signal analysis is resource-intensive. Meanwhile, automated algorithms often overlook EEG's geometric and semantic properties critical…

Signal Processing · Electrical Eng. & Systems 2024-05-17 Arash Hajisafi , Haowen Lin , Yao-Yi Chiang , Cyrus Shahabi

Dynamic networks models describe a growing number of important scientific processes, from cell biology and epidemiology to sociology and finance. There are many aspects of dynamical networks that require statistical considerations. In this…

Methodology · Statistics 2012-05-15 E. C. Wit , A. Abbruzzo

Today, the human brain can be studied as a whole. Electroencephalography, magnetoencephalography, or functional magnetic resonance imaging techniques provide functional connectivity patterns between different brain areas, and during…

Data Analysis, Statistics and Probability · Physics 2011-01-21 Mario Chavez , Miguel Valencia , Vito Latora , Jacques Martinerie

This paper introduces a biomathematical model designed to describe the internal dynamics of dream formation and spontaneous cognitive processes. The model incorporates neurocognitive factors such as dissatisfaction, acceptance, forgetting,…

Neurons and Cognition · Quantitative Biology 2025-05-12 Shirmohammad Tavangari , Sajjad Janfaza , Zahra Shakarami , Aref Yelghi

Deep neural network (DNN) models have demonstrated impressive performance in various domains, yet their application in cognitive neuroscience is limited due to their lack of interpretability. In this study we employ two structurally…

Signal Processing · Electrical Eng. & Systems 2024-09-04 Murat Kucukosmanoglu , Javier O. Garcia , Justin Brooks , Kanika Bansal

The principled design and discovery of biologically- and physically-informed models of neuronal dynamics has been advancing since the mid-twentieth century. Recent developments in artificial intelligence (AI) have accelerated this progress.…

Neurons and Cognition · Quantitative Biology 2021-12-24 Mahta Ramezanian Panahi , Germán Abrevaya , Jean-Christophe Gagnon-Audet , Vikram Voleti , Irina Rish , Guillaume Dumas

The brain is an intricately structured organ responsible for the rich emergent dynamics that support the complex cognitive functions we enjoy as humans. With around $10^{11}$ neurons and $10^{15}$ synapses, understanding how the human brain…

Neurons and Cognition · Quantitative Biology 2019-02-12 Jason Z. Kim , Danielle S. Bassett

Dynamic networks are commonly used in applications where relational data is observed over time. Statistical models for such data should capture not only the temporal dependencies between networks observed in time, but also the structural…

Methodology · Statistics 2017-04-10 Jihui Lee , Gen Li , James D. Wilson

Graph deep learning models, a class of AI-driven approaches employing a message aggregation mechanism, have gained popularity for analyzing the functional brain connectome in neuroimaging. However, their actual effectiveness remains…

Neural and Evolutionary Computing · Computer Science 2026-02-10 Keqi Han , Yao Su , Lifang He , Liang Zhan , Sergey Plis , Vince Calhoun , Carl Yang

The majority of real-world networks are dynamic and extremely large (e.g., Internet Traffic, Twitter, Facebook, ...). To understand the structural behavior of nodes in these large dynamic networks, it may be necessary to model the dynamics…

Social and Information Networks · Computer Science 2015-03-20 Ryan Rossi , Brian Gallagher , Jennifer Neville , Keith Henderson

Human brain functional connectivity (FC) is often measured as the similarity of functional MRI responses across brain regions when a brain is either resting or performing a task. This paper aims to statistically analyze the dynamic nature…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Differential equations are a ubiquitous tool to study dynamics, ranging from physical systems to complex systems, where a large number of agents interact through a graph with non-trivial topological features. Data-driven approximations of…

Statistical Mechanics · Physics 2024-04-26 Vaiva Vasiliauskaite , Nino Antulov-Fantulin

Advancements in artificial intelligence call for a deeper understanding of the fundamental mechanisms underlying deep learning. In this work, we propose a theoretical framework to analyze learning dynamics through the lens of dynamical…

Machine Learning · Computer Science 2025-10-13 Yuchen Lin , Yong Zhang , Sihan Feng , Hong Zhao