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Domain shift is a problem commonly encountered when developing automated histopathology pipelines. The performance of machine learning models such as convolutional neural networks within automated histopathology pipelines is often…

Image and Video Processing · Electrical Eng. & Systems 2021-07-16 Andrew Moyes , Richard Gault , Kun Zhang , Ji Ming , Danny Crookes , Jing Wang

Contrastive learning has gained popularity due to its robustness with good feature representation performance. However, cosine distance, the commonly used similarity metric in contrastive learning, is not well suited to represent the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Jing Wei Tan , Won-Ki Jeong

With the remarkable success of representation learning for prediction problems, we have witnessed a rapid expansion of the use of machine learning and deep learning for the analysis of digital pathology and biopsy image patches. However,…

Machine Learning · Computer Science 2024-03-06 David Ahmedt-Aristizabal , Mohammad Ali Armin , Simon Denman , Clinton Fookes , Lars Petersson

Training a deep learning model to classify histopathological images is challenging, because of the color and shape variability of the cells and tissues, and the reduced amount of available data, which does not allow proper learning of those…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Saypraseuth Mounsaveng , Issam Laradji , David Vázquez , Marco Perdersoli , Ismail Ben Ayed

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Richard J. Chen , Rahul G. Krishnan

In this study, we investigate the performance of few-shot classification models across different domains, specifically natural images and histopathological images. We first train several few-shot classification models on natural images and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Ardhendu Sekhar , Aditya Bhattacharya , Vinayak Goyal , Vrinda Goel , Aditya Bhangale , Ravi Kant Gupta , Amit Sethi

During the past decade, deep neural networks have led to fast-paced progress and significant achievements in computer vision problems, for both academia and industry. Yet despite their success, state-of-the-art image classification…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Aristotelis Ballas , Christos Diou

Domain shift is a well known problem where a model trained on a particular domain (source) does not perform well when exposed to samples from a different domain (target). Unsupervised methods that can adapt to domain shift are highly…

Computer Vision and Pattern Recognition · Computer Science 2021-08-04 Botos Csaba , Xiaojuan Qi , Arslan Chaudhry , Puneet Dokania , Philip Torr

The lack of well-annotated datasets in computational pathology (CPath) obstructs the application of deep learning techniques for classifying medical images. %Since pathologist time is expensive, dataset curation is intrinsically difficult.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Ryan Zhang , Jiadai Zhu , Stephen Yang , Mahdi S. Hosseini , Angelo Genovese , Lina Chen , Corwyn Rowsell , Savvas Damaskinos , Sonal Varma , Konstantinos N. Plataniotis

Despite remarkable success in a variety of applications, it is well-known that deep learning can fail catastrophically when presented with out-of-distribution data. Toward addressing this challenge, we consider the domain generalization…

Machine Learning · Statistics 2021-11-16 Alexander Robey , George J. Pappas , Hamed Hassani

Transfer learning is a standard technique to improve performance on tasks with limited data. However, for medical imaging, the value of transfer learning is less clear. This is likely due to the large domain mismatch between the usual…

Convolutional Neural Networks can be designed with different levels of complexity depending upon the task at hand. This paper analyzes the effect of dimensional changes to the CNN architecture on its performance on the task of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Shreyas Rajesh Labhsetwar , Alistair Michael Baretto , Raj Sunil Salvi , Piyush Arvind Kolte , Veerasai Subramaniam Venkatesh

Standard supervised machine learning assumes that the distribution of the source samples used to train an algorithm is the same as the one of the target samples on which it is supposed to make predictions. However, as any data scientist…

Machine Learning · Computer Science 2020-02-12 Pirmin Lemberger , Ivan Panico

This paper presents an autoencoder-based neural network architecture to compress histopathological images while retaining the denser and more meaningful representation of the original images. Current research into improving compression…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Agnes Barsi , Suvendu Chandan Nayak , Sasmita Parida , Raj Mani Shukla

Deep learning has demonstrated remarkable performance across various tasks in medical imaging. However, these approaches primarily focus on supervised learning, assuming that the training and testing data are drawn from the same…

Image and Video Processing · Electrical Eng. & Systems 2023-08-03 Suruchi Kumari , Pravendra Singh

This paper investigates the critical problem of representation similarity evolution during cross-domain transfer learning, with particular focus on understanding why pre-trained models maintain effectiveness when adapted to medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Wenqiang Zu , Shenghao Xie , Hao Chen , Lei Ma

This study investigates the critical problem of overfitting in deep learning models applied to histopathology image analysis. We show that simply adopting and fine-tuning large-scale models designed for natural image analysis often leads to…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Saghir Alfasly , Ghazal Alabtah , H. R. Tizhoosh

Deep learning has transformed computer vision but relies heavily on large labeled datasets and computational resources. Transfer learning, particularly fine-tuning pretrained models, offers a practical alternative; however, models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Iván Matas , Carmen Serrano , Miguel Nogales , David Moreno , Lara Ferrándiz , Teresa Ojeda , Begoña Acha

Machine learning techniques are steadily becoming more important in modern biology, and are used to build predictive models, discover patterns, and investigate biological problems. However, models trained on one dataset are often not…

Quantitative Methods · Quantitative Biology 2024-05-30 Seyedmehdi Orouji , Martin C. Liu , Tal Korem , Megan A. K. Peters

A deep learning model trained on some labeled data from a certain source domain generally performs poorly on data from different target domains due to domain shifts. Unsupervised domain adaptation methods address this problem by alleviating…

Image and Video Processing · Electrical Eng. & Systems 2019-08-30 Junlin Yang , Nicha C. Dvornek , Fan Zhang , Julius Chapiro , MingDe Lin , James S. Duncan