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Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

Experimental methods based on single particle tracking (SPT) are being increasingly employed in the physical and biological sciences, where nanoscale objects are visualized with high temporal and spatial resolution. SPT can probe…

Statistical Mechanics · Physics 2015-06-12 Denis Boyer , David S. Dean , Carlos Mejía-Monasterio , Gleb Oshanin

Positron emission tomography (PET) enables quantification of dynamic physiological processes through time-resolved imaging. In Rb-82 myocardial perfusion PET, kinetic compartment modeling is used to estimate physiological parameters and…

Medical Physics · Physics 2026-04-09 Myungheon Chin , Sarah J Zou , Garry Chinn , Craig S. Levin

This paper investigates the identifiability and estimation of the parameters of the single particle model (SPM) for lithium-ion battery simulation. Identifiability is addressed both in principle and in practice. The approach begins by…

Systems and Control · Computer Science 2018-10-03 Adrien M. Bizeray , Jin-Ho Kim , Stephen R. Duncan , David A. Howey

An experimental setup for consecutive measurement of ion and x-ray absorption in tissue or other materials is introduced. With this setup using a 3D-printed sample container, the reference stopping-power ratio (SPR) of materials can be…

The simulated tempering (ST) is an important method to deal with systems whose phase spaces are hard to sample ergodically. However, it uses accepting probabilities weights which often demand involving and time consuming calculations. Here…

Statistical Mechanics · Physics 2015-05-20 Carlos E. Fiore , M. G. E. da Luz

3D single object tracking is a key issue for robotics. In this paper, we propose a transformer module called Point-Track-Transformer (PTT) for point cloud-based 3D single object tracking. PTT module contains three blocks for feature…

Computer Vision and Pattern Recognition · Computer Science 2021-10-08 Jiayao Shan , Sifan Zhou , Zheng Fang , Yubo Cui

The aim of this study was to optimize the design of a monolithic LGSO scintillation crystal and micro parallel-hole collimator for the development of a small-animal single photon emission computed tomography (SPECT) system with compact…

Medical Physics · Physics 2015-03-13 Joong Hyun Kim , Mikiko Ito , Soo Mee Kim , Seong Jong Hong , Jae Sung Lee

Objective evaluation of new and improved methods for PET imaging requires access to images with ground truth, as can be obtained through simulation studies. However, for these studies to be clinically relevant, it is important that the…

This paper reviewed the machine learning-based studies for quantitative positron emission tomography (PET). Specifically, we summarized the recent developments of machine learning-based methods in PET attenuation correction and low-count…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Tonghe Wang , Yang Lei , Yabo Fu , Walter J. Curran , Tian Liu , Xiaofeng Yang

Transformer-based 3D human pose estimation methods suffer from high computational costs due to the quadratic complexity of self-attention with respect to sequence length. Additionally, pose sequences often contain significant redundancy…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Zenghao Zheng , Lianping Yang , Hegui Zhu , Mingrui Ye

Compliance of member States to the Treaty on the Non-Proliferation of Nuclear Weapons is monitored through nuclear safeguards. The Passive Gamma Emission Tomography system is a novel instrument developed by the International Atomic Energy…

Instrumentation and Detectors · Physics 2021-03-19 Ming Fang , Yoann Altmann , Daniele Della Latta , Massimiliano Salvatori , Angela Di Fulvio

Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…

In recent years, SiPM photoelectric devices have drawn much attention in the domain of time-of-flight-based positron emission tomography (TOF-PET). Using them to construct PET detectors with excellent coincidence time resolution (CTR) is…

Instrumentation and Detectors · Physics 2018-06-08 Liwei Wang , Yonggang Wang , Qiang Cao , Yong Xiao , Chong Liu

The main goal of the JUNO experiment is the determination of the neutrino mass ordering. To achieve this, an extraordinary energy resolution of at least $3\,\%$ at $1\,$MeV is required for which all parts of the JUNO detector need to meet…

This study presents a real-world canine heart sound dataset and evaluates SoNUS version 3.2.x, a machine learning algorithm for preliminary cardiac analysis using smartphone microphone recordings. More than one hundred recordings were…

Signal Processing · Electrical Eng. & Systems 2026-01-21 Aswin Jose , Roeland P. J. E. Decorte , Laurent Locquet

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

Machine Learning · Computer Science 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

Current clinical PET systems utilize detectors where the scintillator typically contains single elements of 3 - 6 mm width and about 20 mm height. While providing good TOF performance, this design limits the spatial resolution and causes…

Instrumentation and Detectors · Physics 2022-11-17 Florian Mueller , Stephan Naunheim , Yannick Kuhl , David Schug , Torsten Solf , Volkmar Schulz

In this work we explore readout architectures for the simultaneous high-resolution timing and bidimensional tracking of charged particles with Resistive Plate Chambers (TOF-tracker) and for the accurate detection of gamma rays for PET…

The present paper proposes a novel computational method for parametric imaging of nuclear medicine data. The mathematical procedure is general enough to work for compartmental models of diverse complexity and is effective in the…

Tissues and Organs · Quantitative Biology 2017-05-15 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana