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Background Analyzing images to accurately estimate the number of different cell types in the brain using automatic methods is a major objective in neuroscience. The automatic and selective detection and segmentation of neurons would be an…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Antonio LaTorre , Lidia Alonso-Nanclares , José María Peña , Javier De Felipe

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

Quantitative Methods · Quantitative Biology 2022-10-05 André O. Françani

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

Over one in three people are affected by neurodegenerative disorders. Neural stem cells, which are multipotent regenerative cells with the potential to differentiate into any of the neural cell types, have immense therapeutic potential for…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Nidhi Parthasarathy , Chandra Suda , Anika Mittal , Ian Young Chen , Ananya Jalihal

Deep learning has proven to be more effective than other methods in medical image analysis, including the seemingly simple but challenging task of segmenting individual cells, an essential step for many biological studies. Comparative…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Livio Corain , Enrico Grisan

Recent studies have demonstrated the superiority of deep learning in medical image analysis, especially in cell instance segmentation, a fundamental step for many biological studies. However, the excellent performance of the neural networks…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Huaqian Wu , Nicolas Souedet , Caroline Jan , Cédric Clouchoux , Thierry Delzescaux

Identification of different neuronal cell types is critical for understanding their contribution to brain functions. Yet, automated and reliable classification of neurons remains a challenge, primarily because of their biological…

Neural and Evolutionary Computing · Computer Science 2020-09-29 Eirini Troullinou , Grigorios Tsagkatakis , Spyridon Chavlis , Gergely Turi , Wen-Ke Li , Attila Losonczy , Panagiotis Tsakalides , Panayiota Poirazi

The brain is likely the most complex organ, given the variety of functions it controls, the number of cells it comprises, and their corresponding diversity. Studying and identifying neurons, the brain's primary building blocks, is a crucial…

Machine Learning · Computer Science 2023-06-02 Ofek Ophir , Orit Shefi , Ofir Lindenbaum

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Identifying and characterizing the patient's blood samples is indispensable in diagnostics of malignance suspicious. A painstaking and sometimes subjective task is used in laboratories to manually classify white blood cells. Neural…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Daouda Diouf , Djibril Seck , Mountaga Diop , Abdoulye Ba

We consider the problem of accurately identifying cell boundaries and labeling individual cells in confocal microscopy images, specifically, 3D image stacks of cells with tagged cell membranes. Precise identification of cell boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Jiaxiang Jiang , Po-Yu Kao , Samuel A. Belteton , Daniel B. Szymanski , B. S. Manjunath

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

In this paper, we consider the problem of automatically segmenting neuronal cells in dual-color confocal microscopy images. This problem is a key task in various quantitative analysis applications in neuroscience, such as tracing cell…

Computer Vision and Pattern Recognition · Computer Science 2017-06-01 Jianxu Chen , Sreya Banerjee , Abhinav Grama , Walter J. Scheirer , Danny Z. Chen

In recent advancement towards computer based diagnostics system, the classification of brain tumor images is a challenging task. This paper mainly focuses on elevating the classification accuracy of brain tumor images with transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2022-06-20 Pramit Dutta , Khaleda Akhter Sathi , Md. Saiful Islam

Cell individualization has a vital role in digital pathology image analysis. Deep Learning is considered as an efficient tool for instance segmentation tasks, including cell individualization. However, the precision of the Deep Learning…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Huaqian Wu , Nicolas Souedet , Zhenzhen You , Caroline Jan , Cédric Clouchoux , Thierry Delzescaux

Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Cell Behavior · Quantitative Biology 2017-10-31 Mo Zhang , Xiang Li , Mengjia Xu , Quanzheng Li

The ability to automatically detect, classify, calculate the size, number, and grade of retinal cells and other biological objects is critically important in eye disease like age-related macular degeneration (AMD). In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2020-10-01 S. M. Hadi Hosseini , Hao Chen , Monica M. Jablonski

The vascular structure of blood vessels is important in diagnosing retinal conditions such as glaucoma and diabetic retinopathy. Accurate segmentation of these vessels can help in detecting retinal objects such as the optic disc and optic…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Abdullah Sarhan , Jon Rokne , Reda Alhajj , Andrew Crichton

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

Quantitative Methods · Quantitative Biology 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach
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