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Differential abundance tests in compositional data are essential and fundamental tasks in various biomedical applications, such as single-cell, bulk RNA-seq, and microbiome data analysis. However, because of the compositional constraint and…

Methodology · Statistics 2022-04-14 Shulei Wang

Interference alignment (IA) techniques mostly attain their degrees of freedom (DoF) benefits as the number of channel extensions tends to infinity. Intuitively, the more interfering signals that need to be aligned, the larger the number of…

Information Theory · Computer Science 2016-06-08 Zainalabedin Samadi , Vahid Tabataba Vakily , Farzan Haddadi

Data augmentation aims to enrich training samples for alleviating the overfitting issue in low-resource or class-imbalanced situations. Traditional methods first devise task-specific operations such as Synonym Substitute, then preset the…

Computation and Language · Computer Science 2021-09-03 Shuhuai Ren , Jinchao Zhang , Lei Li , Xu Sun , Jie Zhou

Metagenomic studies have increasingly utilized sequencing technologies in order to analyze DNA fragments found in environmental samples.One important step in this analysis is the taxonomic classification of the DNA fragments. Conventional…

Genomics · Quantitative Biology 2020-02-11 Andreas Georgiou , Vincent Fortuin , Harun Mustafa , Gunnar Rätsch

It is recognised that the Bayesian approach to inference can not adequately cope with all the types of pre-data beliefs about population quantities of interest that are commonly held in practice. In particular, it generally encounters…

Methodology · Statistics 2021-04-16 Russell J. Bowater

Correlation networks are commonly used to infer associations between microbes and metabolites. The resulting p-values are then corrected for multiple comparisons using existing methods such as the Benjamini and Hochberg procedure to control…

Methodology · Statistics 2025-06-17 Jing Ma

In microbiome and genomic studies, the regression of compositional data has been a crucial tool for identifying microbial taxa or genes that are associated with clinical phenotypes. To account for the variation in sequencing depth, the…

Methodology · Statistics 2021-03-11 Pixu Shi , Yuchen Zhou , Anru R. Zhang

The interpretation of count data originating from the current generation of DNA sequencing platforms requires special attention. In particular, the per-sample library sizes often vary by orders of magnitude from the same sequencing run, and…

Quantitative Methods · Quantitative Biology 2015-06-17 Paul J. McMurdie , Susan Holmes

In financial applications, we often observe both global and local factors that are modeled by a multi-level factor model. When detecting unknown local group memberships under such a model, employing a covariance matrix as an adjacency…

Econometrics · Economics 2024-12-10 Minseog Oh , Donggyu Kim

Fish Feeding Intensity Assessment (FFIA) is crucial in industrial aquaculture management. Recent multi-modal approaches have shown promise in improving FFIA robustness and efficiency. However, these methods face significant challenges when…

Machine Learning · Computer Science 2025-04-22 Meng Cui , Xianghu Yue , Xinyuan Qian , Jinzheng Zhao , Haohe Liu , Xubo Liu , Daoliang Li , Wenwu Wang

Microbial networks, representing microbes as nodes and their interactions as edges, are crucial for understanding community dynamics in various environments. Analyzing microbiome networks is crucial for identifying keystone taxa that play…

Molecular Networks · Quantitative Biology 2025-07-15 Qiyao Yang , Rosa Aghdam , Reed Nelson , Claudia Solís-Lemus

Independent Component Analysis (ICA) aims to recover independent latent variables from observed mixtures thereof. Causal Representation Learning (CRL) aims instead to infer causally related (thus often statistically dependent) latent…

Independent component analysis (ICA) is a fundamental statistical tool used to reveal hidden generative processes from observed data. However, traditional ICA approaches struggle with the rotational invariance inherent in Gaussian…

Machine Learning · Computer Science 2024-08-21 Ignavier Ng , Yujia Zheng , Xinshuai Dong , Kun Zhang

A fundamental problem arising in dense wireless networks is the high co-channel interference. Interference alignment (IA) was recently proposed as an effective way to combat interference in wireless networks. The concept of IA, though, is…

Networking and Internet Architecture · Computer Science 2017-12-12 Konstantinos Dovelos , Boris Bellalta

Independent component analysis (ICA) is a powerful method for blind source separation based on the assumption that sources are statistically independent. Though ICA has proven useful and has been employed in many applications, complete…

Machine Learning · Statistics 2016-10-21 Zois Boukouvalas , Yuri Levin-Schwartz , Tulay Adali

Quantifying diversity is of central importance for the study of structure, function and evolution of microbial communities. The estimation of microbial diversity has received renewed attention with the advent of large-scale metagenomic…

Populations and Evolution · Quantitative Biology 2013-08-06 Bart Haegeman , Jérôme Hamelin , John Moriarty , Peter Neal , Jonathan Dushoff , Joshua S. Weitz

Missing data are a concern in many real world data sets and imputation methods are often needed to estimate the values of missing data, but data sets with excessive missingness and high dimensionality challenge most approaches to…

Machine Learning · Statistics 2021-04-22 Andrew J. Becker , James P. Bagrow

A great deal of effort is currently being devoted to understanding, estimating and removing systematic errors in cosmological data. In the particular case of type Ia supernovae, systematics are starting to dominate the error budget. Here we…

Cosmology and Nongalactic Astrophysics · Physics 2013-04-17 Luca Amendola , Valerio Marra , Miguel Quartin

The availability of high-throughput parallel methods for sequencing microbial communities is increasing our knowledge of the microbial world at an unprecedented rate. Though most attention has focused on determining lower-bounds on the…

Methodology · Statistics 2011-09-15 Manuel Lladser , Raúl Gouet , Jens Reeder

We develop a new modeling framework for Inter-Subject Analysis (ISA). The goal of ISA is to explore the dependency structure between different subjects with the intra-subject dependency as nuisance. It has important applications in…

Methodology · Statistics 2017-09-22 Cong Ma , Junwei Lu , Han Liu