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Artificial intelligence (AI) has demonstrated significant success in automating the detection of glomeruli, the key functional units of the kidney, from whole slide images (WSIs) in kidney pathology. However, existing open-source tools are…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Jialin Yue , Tianyuan Yao , Ruining Deng , Siqi Lu , Junlin Guo , Quan Liu , Mengmeng Yin , Juming Xiong , Haichun Yang , Yuankai Huo

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Whole-Slide Images (WSIs) have revolutionized medical analysis by presenting high-resolution images of the whole tissue slide. Despite avoiding the physical storage of the slides, WSIs require considerable data volume, which makes the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Yu Mao , Jun Wang , Nan Guan , Chun Jason Xue

In modern cancer diagnostics, Whole Slide Imaging (WSI) is widely used to digitize tissue specimens for detailed, high-resolution examination; however, other diagnostic approaches, such as liquid biopsy and molecular testing, are also…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Seyed Kahaki , Alexander R. Webber , Ghada Zamzmi , Adarsh Subbaswamy , Rucha Deshpande , Aldo Badano

Practical automated detection and diagnosis of plant disease from wide-angle images (i.e. in-field images containing multiple leaves using a fixed-position camera) is a very important application for large-scale farm management, in view of…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Katsumasa Suwa , Quan Huu Cap , Ryunosuke Kotani , Hiroyuki Uga , Satoshi Kagiwada , Hitoshi Iyatomi

Oncologists often rely on a multitude of data, including whole-slide images (WSIs), to guide therapeutic decisions, aiming for the best patient outcome. However, predicting the prognosis of cancer patients can be a challenging task due to…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 M Rita Verdelho , Alexandre Bernardino , Catarina Barata

Whole Slide Images (WSIs) play a crucial role in accurate cancer diagnosis and prognosis, as they provide tissue details at the cellular level. However, the rapid growth of computational tasks involving WSIs poses significant challenges.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Doanh C. Bui , Hoai Luan Pham , Vu Trung Duong Le , Tuan Hai Vu , Van Duy Tran , Khang Nguyen , Yasuhiko Nakashima

Considerable morphological phenotyping studies in nephrology have emerged in the past few years, aiming to discover hidden regularities between clinical and imaging phenotypes. Such studies have been largely enabled by deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2020-07-29 Zheyu Zhu , Yuzhe Lu , Ruining Deng , Haichun Yang , Agnes B. Fogo , Yuankai Huo

Using features extracted from networks pretrained on ImageNet is a common practice in applications of deep learning for digital pathology. However it presents the downside of missing domain specific image information. In digital pathology,…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Jacob Gildenblat , Eldad Klaiman

Tumor segmentation stands as a pivotal task in cancer diagnosis. Given the immense dimensions of whole slide images (WSI) in histology, deep learning approaches for WSI classification mainly operate at patch-wise or superpixel-wise level.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Huaqian Wu , Clara Brémond-Martin , Kévin Bouaou , Cédric Clouchoux

This study introduces a new framework for the artificial intelligence-assisted characterization of Gram-stained whole-slide images (WSIs). As a test for the diagnosis of bloodstream infections, Gram stains provide critical early data to…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Jack McMahon , Naofumi Tomita , Elizabeth S. Tatishev , Adrienne A. Workman , Cristina R Costales , Niaz Banaei , Isabella W. Martin , Saeed Hassanpour

The class distribution of data is one of the factors that regulates the performance of machine learning models. However, investigations on the impact of different distributions available in the literature are very few, sometimes absent for…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Ismat Ara Reshma , Sylvain Cussat-Blanc , Radu Tudor Ionescu , Hervé Luga , Josiane Mothe

Whole Slide Image (WSI) analysis, with its ability to reveal detailed tissue structures in magnified views, plays a crucial role in cancer diagnosis and prognosis. Due to their giga-sized nature, WSIs require substantial storage and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Doanh Cao Bui , Jin Tae Kwak

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Deep learning is often applied in settings where data are limited, correlated, and difficult to obtain, yet evaluation practices do not always reflect these constraints. Neuroimaging for prodromal Parkinsons disease is one such case, where…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Naimur Rahman

Digitized histopathology glass slides, known as Whole Slide Images (WSIs), are often several gigapixels large and contain sensitive metadata information, which makes distributed processing unfeasible. Moreover, artifacts in WSIs may result…

Computational Engineering, Finance, and Science · Computer Science 2023-09-14 Yuandou Wang , Neel Kanwal , Kjersti Engan , Chunming Rong , Zhiming Zhao

Accurate segmentation of the glomerular basement membrane (GBM) in electron microscopy (EM) images is fundamental for quantifying membrane thickness and supporting the diagnosis of various kidney diseases. While supervised deep learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Hongjin Fang , Daniel Reisenbüchler , Kenji Ikemura , Mert R. Sabuncu , Yihe Yang , Ruining Deng

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Assessing microsatellite stability status of a patient's colorectal cancer is crucial in personalizing treatment regime. Recently, convolutional-neural-networks (CNN) combined with transfer-learning approaches were proposed to circumvent…

Computer Vision and Pattern Recognition · Computer Science 2022-08-23 Daniel Shats , Hadar Hezi , Guy Shani , Yosef E. Maruvka , Moti Freiman

For many real-world applications involving low-power sensor edge devices deep neural networks used for image classification might not be suitable. This is due to their typically large model size and require- ment of operations often…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Oliver Bause , Julia Werner , Paul Palomero Bernardo , Oliver Bringmann