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In this work we addressed the problem of capturing sequential information contained in longitudinal electronic health records (EHRs). Clinical notes, which is a particular type of EHR data, are a rich source of information and practitioners…

Computation and Language · Computer Science 2020-10-27 Andrey Kormilitzin , Nemanja Vaci , Qiang Liu , Hao Ni , Goran Nenadic , Alejo Nevado-Holgado

In recent years, the trend of deploying digital systems in numerous industries has hiked. The health sector has observed an extensive adoption of digital systems and services that generate significant medical records. Electronic health…

Computation and Language · Computer Science 2022-03-01 Neel Kanwal , Giuseppe Rizzo

Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few…

Machine Learning · Computer Science 2017-10-25 Sanjay Purushotham , Chuizheng Meng , Zhengping Che , Yan Liu

Clinician burnout poses a substantial threat to patient safety, particularly in high-acuity intensive care units (ICUs). Existing research predominantly relies on retrospective survey tools or broad electronic health record (EHR) metadata,…

Computation and Language · Computer Science 2025-09-08 Syed Ahmad Chan Bukhari , Fazel Keshtkar , Alyssa Meczkowska

Time series data are prevalent in electronic health records, mostly in the form of physiological parameters such as vital signs and lab tests. The patterns of these values may be significant indicators of patients' clinical states and there…

Machine Learning · Computer Science 2019-11-18 Kun Zhang , Yuan Xue , Gerardo Flores , Alvin Rajkomar , Claire Cui , Andrew M. Dai

This study investigates the impact of masking strategies on time series imputation models in healthcare settings. While current approaches predominantly rely on random masking for model evaluation, this practice fails to capture the…

Machine Learning · Computer Science 2025-02-05 Linglong Qian , Yiyuan Yang , Wenjie Du , Jun Wang , Richard Dobsoni , Zina Ibrahim

With the improvement of medical data capturing, vast amount of continuous patient monitoring data, e.g., electrocardiogram (ECG), real-time vital signs and medications, become available for clinical decision support at intensive care units…

Machine Learning · Computer Science 2018-07-25 Yanbo Xu , Siddharth Biswal , Shriprasad R Deshpande , Kevin O Maher , Jimeng Sun

Clinical notes contain an extensive record of a patient's health status, such as smoking status or the presence of heart conditions. However, this detail is not replicated within the structured data of electronic health systems.…

Computation and Language · Computer Science 2020-09-18 Andriy Mulyar , Elliot Schumacher , Masoud Rouhizadeh , Mark Dredze

Intensive Care Unit (ICU) patients often present with complex, overlapping signs of physiological deterioration that require timely escalation of care. Traditional early warning systems, such as SOFA or MEWS, are limited by their focus on…

Machine Learning · Computer Science 2025-09-24 Syed Ahmad Chan Bukhari , Amritpal Singh , Shifath Hossain , Iram Wajahat

Current deep learning based disease diagnosis systems usually fall short in catastrophic forgetting, i.e., directly fine-tuning the disease diagnosis model on new tasks usually leads to abrupt decay of performance on previous tasks. What is…

Artificial Intelligence · Computer Science 2021-03-08 Zifeng Wang , Yifan Yang , Rui Wen , Xi Chen , Shao-Lun Huang , Yefeng Zheng

Large pre-trained language models (LMs) have been widely adopted in biomedical and clinical domains, introducing many powerful LMs such as bio-lm and BioELECTRA. However, the applicability of these methods to real clinical use cases is…

Computation and Language · Computer Science 2022-11-16 Samuel Cahyawijaya , Bryan Wilie , Holy Lovenia , Huan Zhong , MingQian Zhong , Yuk-Yu Nancy Ip , Pascale Fung

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Intensive Care in-hospital mortality prediction has various clinical applications. Neural prediction models, especially when capitalising on clinical notes, have been put forward as improvement on currently existing models. However, to be…

Computation and Language · Computer Science 2022-12-14 Miguel Rios , Ameen Abu-Hanna

ICU mortality scoring systems attempt to predict patient mortality using predictive models with various clinical predictors. Examples of such systems are APACHE, SAPS and MPM. However, most such scoring systems do not actively look for and…

Neural and Evolutionary Computing · Computer Science 2016-04-25 Chee Chun Gan , Gerard Learmonth

Computerised clinical coding approaches aim to automate the process of assigning a set of codes to medical records. While there is active research pushing the state of the art on clinical coding for hospitalized patients, the outpatient…

Time series data from the Intensive Care Unit (ICU) provides critical information for patient monitoring. While recent advancements in applying Large Language Models (LLMs) to time series modeling (TSM) have shown great promise, their…

Machine Learning · Computer Science 2026-01-27 Feixiang Zheng , Yu Wu , Cecilia Mascolo , Ting Dang

Severe sepsis and septic shock are conditions that affect millions of patients and have close to 50% mortality rate. Early identification of at-risk patients significantly improves outcomes. Electronic surveillance tools have been developed…

Computers and Society · Computer Science 2018-09-12 Emilia Apostolova , Tom Velez

The multivariate, asynchronous nature of real-world clinical data, such as that generated in Intensive Care Units (ICUs), challenges traditional AI-based decision-support systems. These often assume data regularity and feature independence…

Machine Learning · Computer Science 2025-02-28 Ricardo Santos , André V. Carreiro , Xi Peng , Hugo Gamboa , Holger Fröhlich

Responding rapidly to a patient who is demonstrating signs of imminent clinical deterioration is a basic tenet of patient care. This gave rise to a patient safety intervention philosophy known as a Rapid Response System (RRS), whereby a…

Machine Learning · Computer Science 2021-02-12 Laleh Jalali , Hsiu-Khuern Tang , Richard H. Goldstein , Joaqun Alvarez Rodrguez

ICU readmission is associated with longer hospitalization, mortality and adverse outcomes. An early recognition of ICU re-admission can help prevent patients from worse situation and lower treatment cost. As the abundance of Electronics…

Machine Learning · Computer Science 2019-10-08 Zhiheng Li , Xinyue Xing , Bingzhang Lu , Zhixiang Li
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