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Left ventricular ejection fraction (LVEF) is the most important clinical parameter of cardiovascular function. The accuracy in estimating this parameter is highly dependent upon the precise segmentation of the left ventricle (LV) structure…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Narjes Benameur , Ramzi Mahmoudi , Mohamed Deriche , Amira fayouka , Imene Masmoudi , Nessrine Zoghlami

Cardiac left ventricle (LV) quantification provides a tool for diagnosing cardiac diseases. Automatic calculation of all relevant LV indices from cardiac MR images is an intricate task due to large variations among patients and deformation…

Image and Video Processing · Electrical Eng. & Systems 2020-02-04 Nils Gessert , Alexander Schlaefer

Several cardiovascular diseases are caused from localised abnormal blood flow such as in the case of stenosis or aneurysms. Prevailing theories propose that the development is caused by abnormal wall-shear stress in focused areas.…

Optimization and Control · Mathematics 2016-07-12 S. W. Funke , M. Nordaas , Øyvind Evju , M. S. Alnæs , K. -A. Mardal

We propose a method for multi-scale hybrid simulations of molecular dynamics (MD) and computational fluid dynamics (CFD). In the method, usual lattice-mesh based simulations are applied for CFD level, but each lattice is associated with a…

Soft Condensed Matter · Physics 2014-01-20 Shugo Yasuda , Ryoichi Yamamoto

Accurate segmentation of heart structures imaged by cardiac MR is key for the quantitative analysis of pathology. High-resolution 3D MR sequences enable whole-heart structural imaging but are time-consuming, expensive to acquire and they…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Carlo Biffi , Juan J. Cerrolaza , Giacomo Tarroni , Antonio de Marvao , Stuart A. Cook , Declan P. O'Regan , Daniel Rueckert

Cardiac imaging known as echocardiography is a non-invasive tool utilized to produce data including images and videos, which cardiologists use to diagnose cardiac abnormalities in general and myocardial infarction (MI) in particular.…

Image and Video Processing · Electrical Eng. & Systems 2022-08-05 Oumaima Hamila , Sheela Ramanna , Christopher J. Henry , Serkan Kiranyaz , Ridha Hamila , Rashid Mazhar , Tahir Hamid

Cardiac disease evaluation depends on multiple diagnostic modalities: electrocardiogram (ECG) to diagnose abnormal heart rhythms, and imaging modalities such as Magnetic Resonance Imaging (MRI), Computed Tomography (CT) and echocardiography…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Evariste Njomgue Fotso , Buntheng Ly , Hubert Cochet , Maxime Sermesant

Computational fluid dynamics (CFD) simulation is an irreplaceable modelling step in many engineering designs, but it is often computationally expensive. Some graph neural network (GNN)-based CFD methods have been proposed. However, the…

Machine Learning · Computer Science 2023-11-27 Loh Sher En Jessica , Naheed Anjum Arafat , Wei Xian Lim , Wai Lee Chan , Adams Wai Kin Kong

Mechano-electric feedbacks (MEFs), which model how mechanical stimuli are transduced into electrical signals, have received sparse investigation by considering electromechanical simulations in simplified scenarios. In this paper, we study…

Numerical Analysis · Mathematics 2021-11-01 Matteo Salvador , Francesco Regazzoni , Stefano Pagani , Luca Dede' , Natalia Trayanova , Alfio Quarteroni

The 3D volumetric shape of the heart's left ventricle (LV) myocardium (MYO) wall provides important information for diagnosis of cardiac disease and invasive procedure navigation. Many cardiac image segmentation methods have relied on…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Meng Ye , Qiaoying Huang , Dong Yang , Pengxiang Wu , Jingru Yi , Leon Axel , Dimitris Metaxas

4D Flow is an MRI sequence which allows acquisition of 3D images of the heart. The data is typically acquired volumetrically, so it must be reformatted to generate cardiac long axis and short axis views for diagnostic interpretation. These…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Matthieu Le , Jesse Lieman-Sifry , Felix Lau , Sean Sall , Albert Hsiao , Daniel Golden

Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, yet early risk detection is often limited by available diagnostics. Carotid ultrasound, a non-invasive and widely accessible modality, encodes rich structural…

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

Numerical Analysis · Mathematics 2022-08-12 Michele Bucelli , Alberto Zingaro , Pasquale Claudio Africa , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

We performed numerical simulations of blood flow in arteries with a variable stiffness and cross-section at rest using a finite volume method coupled with a hydrostatic reconstruction of the variables at the interface of each mesh cell. The…

Numerical Analysis · Mathematics 2015-09-15 Olivier Delestre , Arthur Ghigo , Jose-Maria Fullana , Pierre-Yves Lagrée

The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…

Medical Physics · Physics 2023-08-03 Sebastian Skatulla , Carlo Sansour , Mary Familusi , Jagir Hussan , Ntobeko Ntusi

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…

Quantitative Methods · Quantitative Biology 2025-08-27 Daehyun Kim , Jeffrey Tithof

A part of non-Newtonian fluids are yield stress fluids. They require a minimum stress to flow. Below this minimum value, yield stress fluids remain solid. To date, 1D and 2D numerical models have been used predominantly to study free…

Fluid Dynamics · Physics 2018-08-03 N Schaer , J. Vazquez , M. Dufresne , G Isenmann , J. Wertel

Two crucial factors for accurate numerical simulations of cardiac electromechanics, which are also essential to reproduce the synchronous activity of the heart, are: i) accounting for the interaction between the heart and the circulatory…