Related papers: A hybrid echocardiography-computational fluid dyna…
Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…
Local hemodynamic forces play an important role in determining the functional significance of coronary arterial stenosis and understanding the mechanism of coronary disease progression. Computational fluid dynamics (CFD) have been widely…
Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…
Intraventricular vector flow mapping (iVFM) is a technique for retrieving 2-D velocity vector fields of blood flow in the left ventricle. This method is based on conventional color Doppler imaging, which makes iVFM compatible with the…
3D echocardiography is an increasingly popular tool for assessing cardiac remodelling in the right ventricle (RV). It allows quantification of the cardiac chambers without any geometric assumptions, which is the main weakness of 2D…
Background: Computational fluid dynamics (CFD) has become an essential design tool for ventricular assist devices (VADs), where the goal of maximizing performance often conflicts with biocompatibility. This tradeoff becomes even more…
Echocardiography (echo) plays an indispensable role in the clinical practice of heart diseases. However, ultrasound imaging typically provides only two-dimensional (2D) cross-sectional images from a few specific views, making it challenging…
Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…
Fluid flow is a widely applied physical problem, crucial in various fields. Due to the highly nonlinear and chaotic nature of fluids, analyzing fluid-related problems is exceptionally challenging. Computational fluid dynamics (CFD) is the…
Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically…
Computational cardiovascular flow modeling plays a crucial role in understanding blood flow dynamics. While 3D models provide acute details, they are computationally expensive, especially with fluid-structure interaction (FSI) simulations.…
This work presents a biventricular electromechanical human heart model that is comprehensive and clinically relevant, integrating a realistic 3D heart geometry with both systemic and pulmonary hemodynamics. The model uses a two-way…
Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…
Accurate 3D cardiac reconstruction from cine magnetic resonance imaging (cMRI) is crucial for improved cardiovascular disease diagnosis and understanding of the heart's motion. However, current cardiac MRI-based reconstruction technology…
Left ventricular ejection fraction (LVEF) is a key indicator of cardiac function and plays a central role in the diagnosis and management of cardiovascular disease. Echocardiography, as a readily accessible and non-invasive imaging…
Conventional cardiovascular magnetic resonance (CMR) cine imaging relies on binning multiple heartbeats into a single cardiac cycle, which fails in arrhythmic patients where beat-to-beat variability causes motion artifacts and loss of…
This study investigates the hemodynamic behavior of blood flow in the aortic arch across anemic, diabetic, and healthy conditions using computational fluid dynamics (CFD) simulations with a non-Newtonian Carreau viscosity model. Velocity…
Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…
We developed a novel patient-specific computational model for the numerical simulation of ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model reproduces the activity both in sinus rhythm (SR) and in…
Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…