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The burgeoning growth of open-sourced vision-language models (VLMs) has catalyzed a plethora of applications across diverse domains. Ensuring the transparency and interpretability of these models is critical for fostering trustworthy and…

Neurons and Cognition · Quantitative Biology 2025-09-25 Jiaqi Xu , Cuiling Lan , Yan Lu

Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables. It has been previously proposed that non-linear…

Neurons and Cognition · Quantitative Biology 2016-04-25 Jeff Hawkins , Subutai Ahmad

Over repeat presentations of the same stimulus, sensory neurons show variable responses. This "noise" is typically correlated between pairs of cells, and a question with rich history in neuroscience is how these noise correlations impact…

Neurons and Cognition · Quantitative Biology 2015-06-16 Yu Hu , Joel Zylberberg , Eric Shea-Brown

In many animal sensory pathways, the transformation from external stimuli to spike trains is essentially deterministic. In this context, a new mathematical framework for coding and reconstruction, based on a biologically plausible model of…

Neurons and Cognition · Quantitative Biology 2019-08-01 Anik Chattopadhyay , Arunava Banerjee

The impressive performance of Convolutional Neural Networks (CNNs) when solving different vision problems is shadowed by their black-box nature and our consequent lack of understanding of the representations they build and how these…

Computer Vision and Pattern Recognition · Computer Science 2019-10-16 Ivet Rafegas , Maria Vanrell , Luis A. Alexandre , Guillem Arias

When neural networks are trained to classify a dataset, one finds a set of weights from which the network produces a label for each data point. We study the algorithmic complexity of finding a collision in a single-layer neural net, where a…

In this article, we review a class of neuro-mimetic computational models that we place under the label of spiking predictive coding. Specifically, we review the general framework of predictive processing in the context of neurons that emit…

Neurons and Cognition · Quantitative Biology 2024-09-10 Antony W. N'dri , William Gebhardt , Céline Teulière , Fleur Zeldenrust , Rajesh P. N. Rao , Jochen Triesch , Alexander Ororbia

Understanding what individual neurons encode is a core question in neuroscience. In primary visual cortex (V1), mathematical models (e.g., Gabor functions) capture neural selectivity, but no comparable framework exists for higher areas. We…

Neurons and Cognition · Quantitative Biology 2026-05-19 Vedang Lad , Katrin Franke , Tamar Rott Shaham , Surya Ganguli , Andreas S. Tolias , Sophia Sanborn , Nikos Karantzas

Recent in vitro data show that neurons respond to input variance with varying sensitivities. Here, we demonstrate that Hodgkin-Huxley (HH) neurons can operate in two computational regimes, one that is more sensitive to input variance…

Neurons and Cognition · Quantitative Biology 2007-07-17 Brian Nils Lundstrom , Sungho Hong , Matthew H. Higgs , Adrienne L. Fairhall

Human brains are arguably the most complex entities known. Composed of billions of neurons, connected via a highly detailed structure where the underlying method by which functionality occurs is still debated. Here we consider one theory…

Neurons and Cognition · Quantitative Biology 2019-03-26 Jon Borresen , Killian O'Brien

Combinatorial neural codes are $0/1$ vectors that are used to model the co-firing patterns of a set of place cells in the brain. One wide-open problem in this area is to determine when a given code can be algorithmically drawn in the plane…

Combinatorics · Mathematics 2018-08-29 Robert Davis

It is commonly recognized that the expressiveness of deep neural networks is contingent upon a range of factors, encompassing their depth, width, and other relevant considerations. Currently, the practical performance of the majority of…

Machine Learning · Computer Science 2023-11-08 Xuan Qi , Yi Wei

Recent success in training deep neural networks have prompted active investigation into the features learned on their intermediate layers. Such research is difficult because it requires making sense of non-linear computations performed by…

Machine Learning · Computer Science 2016-03-01 Yixuan Li , Jason Yosinski , Jeff Clune , Hod Lipson , John Hopcroft

Discussions of the hippocampus often focus on place cells, but many neurons are not place cells in any given environment. Here we describe the collective activity in such mixed populations, treating place and non-place cells on the same…

Neurons and Cognition · Quantitative Biology 2019-01-01 Leenoy Meshulam , Jeffrey L. Gauthier , Carlos D. Brody , David W. Tank , William Bialek

Much of the information the brain processes and stores is temporal in nature - a spoken word or a handwritten signature, for example, is defined by how it unfolds in time. However, it remains unclear how neural circuits encode complex…

Neurons and Cognition · Quantitative Biology 2017-08-15 Vishwa Goudar , Dean Buonomano

Sequences of neuronal activation have long been implicated in a variety of brain functions. In particular, these sequences have been tied to memory formation and spatial navigation in the hippocampus, a region of mammalian brains.…

Neurons and Cognition · Quantitative Biology 2016-03-10 Zachary Roth

Brette (2019) criticizes the notion of neural coding because it seems to entail that neural signals need to be decoded by or for some receiver in the head. If that were so, then neural coding would indeed be homuncular (Brette calls it…

Neurons and Cognition · Quantitative Biology 2019-12-04 Stevan Harnad

Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

It is a principal open question whether noninvasive imaging methods in humans can decode information encoded at a spatial scale as fine as the basic functional unit of cortex: cortical columns. We addressed this question in five…

Neurons and Cognition · Quantitative Biology 2015-03-30 Radoslaw Martin Cichy , Dimitrios Pantazis

Hyperdimensional Computing affords simple, yet powerful operations to create long Hyperdimensional Vectors (hypervectors) that can efficiently encode information, be used for learning, and are dynamic enough to be modified on the fly. In…

Symbolic Computation · Computer Science 2022-06-01 Peter Sutor , Dehao Yuan , Douglas Summers-Stay , Cornelia Fermuller , Yiannis Aloimonos
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