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Magnetic resonance (MR) and computer tomography (CT) images are two typical types of medical images that provide mutually-complementary information for accurate clinical diagnosis and treatment. However, obtaining both images may be limited…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Jiayuan Wang , Q. M. Jonathan Wu , Farhad Pourpanah

CT is commonly used in orthopedic procedures. MRI is used along with CT to identify muscle structures and diagnose osteonecrosis due to its superior soft tissue contrast. However, MRI has poor contrast for bone structures. Clearly, it would…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Yuta Hiasa , Yoshito Otake , Masaki Takao , Takumi Matsuoka , Kazuma Takashima , Jerry L. Prince , Nobuhiko Sugano , Yoshinobu Sato

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

Providing more precise tissue attenuation information, synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) contributes to improved radiation therapy treatment planning. In our study, we employ the advanced…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Fuxin Fan , Jingna Qiu , Yixing Huang , Andreas Maier

This paper strives to generate a synthetic computed tomography (CT) image from a magnetic resonance (MR) image. The synthetic CT image is valuable for radiotherapy planning when only an MR image is available. Recent approaches have made…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Zenglin Shi , Pascal Mettes , Guoyan Zheng , Cees Snoek

A Magnetic Resonance Imaging (MRI) exam typically consists of the acquisition of multiple MR pulse sequences, which are required for a reliable diagnosis. Each sequence can be parameterized through multiple acquisition parameters affecting…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Jonas Denck , Jens Guehring , Andreas Maier , Eva Rothgang

Computed tomography (CT) can provide a 3D view of the patient's internal organs, facilitating disease diagnosis, but it incurs more radiation dose to a patient and a CT scanner is much more cost prohibitive than an X-ray machine too.…

Image and Video Processing · Electrical Eng. & Systems 2019-05-17 Xingde Ying , Heng Guo , Kai Ma , Jian Wu , Zhengxin Weng , Yefeng Zheng

Computed tomography (CT) is essential for treatment and diagnostics; In case CT are missing or otherwise difficult to obtain, methods for generating synthetic CT (sCT) images from magnetic resonance imaging (MRI) images are sought after.…

Image and Video Processing · Electrical Eng. & Systems 2025-09-29 Emily Honey , Anders Helbo , Jens Petersen

AI requires extensive datasets, while medical data is subject to high data protection. Anonymization is essential, but poses a challenge for some regions, such as the head, as identifying structures overlap with regions of clinical…

Accurate synthesis of computed tomography (CT) images from magnetic resonance imaging (MRI) is clinically valuable for cranial applications such as attenuation correction, radiotherapy planning, and image-guided interventions. However,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Zhuoyao Xin , Yiren Zhang , Christopher Wu , Dong Liu , Chunming Gu , Elena Greco , Erik H. Middlebrooks , Jun Hua , Jia Guo

Model-based treatment planning for transcranial ultrasound therapy typically involves mapping the acoustic properties of the skull from an x-ray computed tomography (CT) image of the head. Here, three methods for generating pseudo-CT images…

Cone-Beam Computed Tomography (CBCT) is widely used for real-time intraoperative imaging due to its low radiation dose and high acquisition speed. However, despite its high resolution, CBCT suffers from significant artifacts and thereby…

Image and Video Processing · Electrical Eng. & Systems 2025-06-11 Maximilian Tschuchnig , Lukas Lamminger , Philipp Steininger , Michael Gadermayr

Supervised synthetic CT generation from CBCT requires registered training pairs, yet perfect registration between separately acquired scans remains unattainable. This registration bias propagates into trained models and corrupts standard…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lukas Zimmermann , Michael Rauter , Maximilian Schmid , Dietmar Georg , Barbara Knäusl

Acquiring images of the same anatomy with multiple different contrasts increases the diversity of diagnostic information available in an MR exam. Yet, scan time limitations may prohibit acquisition of certain contrasts, and images for some…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Salman Ul Hassan Dar , Mahmut Yurt , Levent Karacan , Aykut Erdem , Erkut Erdem , Tolga Çukur

MRI provides superior soft tissue contrast without ionizing radiation; however, the absence of electron density information limits its direct use for dose calculation. As a result, current radiotherapy workflows rely on combined MRI and CT…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Zolnamar Dorjsembe , Hung-Yi Chen , Furen Xiao , Hsing-Kuo Pao

Cone-Beam Computed Tomography (CBCT) is widely used for intraoperative imaging due to its rapid acquisition and low radiation dose. However, CBCT images typically suffer from artifacts and lower visual quality compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Maximilian Tschuchnig , Lukas Lamminger , Philipp Steininger , Michael Gadermayr

Accurate MR-to-CT synthesis is a requirement for MR-only workflows in radiotherapy (RT) treatment planning. In recent years, deep learning-based approaches have shown impressive results in this field. However, to prevent downstream errors…

Image and Video Processing · Electrical Eng. & Systems 2019-11-13 Louis D. van Harten , Jelmer M. Wolterink , Joost J. C. Verhoeff , Ivana Išgum

Anatomical structures such as blood vessels in contrast-enhanced CT (ceCT) images can be challenging to segment due to the variability in contrast medium diffusion. The combined use of ceCT and contrast-free (CT) CT images can improve the…

Image and Video Processing · Electrical Eng. & Systems 2022-10-05 Giammarco La Barbera , Haithem Boussaid , Francesco Maso , Sabine Sarnacki , Laurence Rouet , Pietro Gori , Isabelle Bloch

With the increasing popularity of PET-MR scanners in clinical applications, synthesis of CT images from MR has been an important research topic. Accurate PET image reconstruction requires attenuation correction, which is based on the…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Snehashis Roy , John A. Butman , Dzung L. Pham

In medical imaging, image synthesis is the estimation process of one image (sequence, modality) from another image (sequence, modality). Since images with different modalities provide diverse biomarkers and capture various features,…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Firoozeh Shomal Zadeh , Sevda Molani , Maysam Orouskhani , Marziyeh Rezaei , Mehrzad Shafiei , Hossein Abbasi