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Predictions of relative stabilities of (competing) molecular crystals are of great technological relevance, most notably for the pharmaceutical industry. However, they present a long-standing challenge for modeling, as often minuscule free…

Materials Science · Physics 2022-05-25 Venkat Kapil , Edgar A Engel

The genomics approach to materials, heralded by increasingly accurate density functional theory (DFT) calculations conducted on thousands of crystalline compounds, has led to accelerated material discovery and property predictions. However,…

Materials Science · Physics 2024-06-12 Mariana Fazio , Le Yang , Carmen S. Menoni

Accurate molecular crystal structure prediction is a fundamental goal in academic and industrial condensed matter research and polymorphism is arguably the biggest obstacle on the way. We tackle this challenge in the difficult case of the…

Materials Science · Physics 2016-05-04 Cong Huy Pham , Emine Kucukbenli , Stefano de Gironcoli

The use of machine learning methods for accelerating the design of crystalline materials usually requires manually constructed feature vectors or complex transformation of atom coordinates to input the crystal structure, which either…

Materials Science · Physics 2018-04-10 Tian Xie , Jeffrey C. Grossman

Crystal structure prediction algorithms have become powerful tools for materials discovery in recent years, however, they are usually limited to relatively small systems. The main challenge is that the number of local minima grows…

Materials Science · Physics 2022-02-09 Hao Gao , Junjie Wang , Yu Han , Jian Sun

Traditional materials discovery approaches - relying primarily on laborious experiments - have controlled the pace of technology. Instead, computational approaches offer an accelerated path: high-throughput exploration and characterization…

Materials Science · Physics 2018-11-23 Corey Oses

Predicting the stability of crystals is one of the central problems in materials science. Today, density functional theory (DFT) calculations are the computational tool of choice to obtain energies of crystals with quantitative accuracy.…

Materials Science · Physics 2018-11-14 Weike Ye , Chi Chen , Zhenbin Wang , Iek-Heng Chu , Shyue Ping Ong

Crystal structures are indispensable across various domains, from batteries to solar cells, and extensive research has been dedicated to predicting their properties based on their atomic configurations. However, prevailing Crystal Structure…

Neural and Evolutionary Computing · Computer Science 2024-06-24 Hannah Janmohamed , Marta Wolinska , Shikha Surana , Thomas Pierrot , Aron Walsh , Antoine Cully

Crystal structure prediction has traditionally relied on prototype-based seeding, approaches that often bias sampling toward known low-energy basins and overlook metastable polymorphs with unconventional symmetries. Here, we introduce…

Materials Science · Physics 2026-04-24 Jiexi Song , Diwei Shi , Aixian She , Chongde Cao , Fengyuan Xuan

The rapid adoption of machine learning (ML) in domain sciences necessitates best practices and standardized benchmarking for performance evaluation. We present Matbench Discovery, an evaluation framework for ML energy models, applied as…

Devising a computational tool that assesses the thermodynamic stability of materials is among the most important steps required to build a ``virtual laboratory'', where materials could be designed from first-principles without relying on…

Statistical Mechanics · Physics 2007-05-23 A. van de Walle , G. Ceder

Evolutionary crystal structure prediction proved to be a powerful approach for studying a wide range of materials. Here, we present a specifically designed algorithm for the prediction of the structure of complex crystals consisting of…

Materials Science · Physics 2012-05-21 Qiang Zhu , Artem R. Oganov , Colin W. Glass , Harold T. Stokes

Crystal structure prediction (CSP) stands as a powerful tool in materials science, driving the discovery and design of innovative materials. However, existing CSP methods heavily rely on formation enthalpies derived from density functional…

Materials Science · Physics 2025-07-16 Chenglong Qin , Jinde Liu , Shiyin Ma , Jiguang Du , Gang Jiang , Liang Zhao

High-through computational thermodynamic approaches are becoming an increasingly popular tool to uncover novel compounds. However, traditional methods tend to be limited to stability predictions of stoichiometric phases at absolute zero.…

Materials Science · Physics 2022-04-20 Sayan Samanta , Axel Van de Walle

Polymorphism, the ability of a compound to crystallize in multiple distinct structures, plays a vital role in determining the physical, chemical, and functional properties of materials. Accurate identification and prediction of polymorphic…

Materials Science · Physics 2025-08-15 Sourin Dey , Nicholas Miklaucic , Sadman Sadeed Omee , Rongzhi Dong , Lai Wei , Qinyang Li , Nihang Fu , Jianjun Hu

Atomically thin 2-dimensional heterostructures are a promising, novel class of materials with groundbreaking properties. The possiblity of choosing the many constituent components and their proportions allows optimizing these materials to…

Mesoscale and Nanoscale Physics · Physics 2019-10-23 Petri Hirvonen , Vili Heinonen , Haikuan Dong , Zheyong Fan , Ken R. Elder , Tapio Ala-Nissila

A thorough in situ characterization of materials at extreme conditions is challenging, and computational tools such as crystal structural search methods in combination with ab initio calculations are widely used to guide experiments by…

Materials Science · Physics 2018-11-14 Maximilian Amsler , Vinay I. Hegde , Steven D. Jacobsen , Chris Wolverton

The evaluation of phase stabilities of unstable elemental phases is a long-standing problem in the computational assessment of phase diagrams. Here we tackle this problem by explicitly calculating phase diagrams of intermetallic systems…

Materials Science · Physics 2016-09-20 Shmuel Barzilai , Cormac Toher , Stefano Curtarolo , Ohad Levy

A systematic search for multicomponent crystal structures is carried out for five different ternary systems of nuclei in a polarizable background of electrons, representative of accreted neutron star crusts and some white dwarfs. Candidate…

High Energy Astrophysical Phenomena · Physics 2016-03-09 T. A. Engstrom , N. C. Yoder , V. H. Crespi

Perovskite materials have become ubiquitous in many technologically relevant applications, ranging from catalysts in solid oxide fuel cells to light absorbing layers in solar photovoltaics. The thermodynamic phase stability is a key…

Materials Science · Physics 2018-06-05 Wei Li , Ryan Jacobs , Dane Morgan