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Predicting drug-drug interactions (DDI) is the problem of predicting side effects (unwanted outcomes) of a pair of drugs using drug information and known side effects of many pairs. This problem can be formulated as predicting labels (i.e.…

Machine Learning · Computer Science 2023-04-05 Duc Anh Nguyen , Canh Hao Nguyen , Hiroshi Mamitsuka

Motivation: The biomedical literature contains a wealth of chemical-protein interactions (CPIs). Automatically extracting CPIs described in biomedical literature is essential for drug discovery, precision medicine, as well as basic…

Computation and Language · Computer Science 2020-04-27 Cong Sun , Zhihao Yang , Leilei Su , Lei Wang , Yin Zhang , Hongfei Lin , Jian Wang

Biological data are extremely diverse, complex but also quite sparse. The recent developments in deep learning methods are offering new possibilities for the analysis of complex data. However, it is easy to be get a deep learning model that…

Machine Learning · Computer Science 2019-01-21 Florian Richoux , Charlène Servantie , Cynthia Borès , Stéphane Téletchéa

The objective of our work is to demonstrate the feasibility of utilizing deep learning models to extract safety signals related to the use of dietary supplements (DS) in clinical text. Two tasks were performed in this study. For the named…

Information Retrieval · Computer Science 2020-11-24 Yadan Fan , Sicheng Zhou , Yifan Li , Rui Zhang

Depression places substantial pressure on mental health services, and many people describe their experiences outside clinical settings in high-volume user-generated text (e.g., online forums and social media). Automatically identifying…

Computation and Language · Computer Science 2026-04-28 Eliseo Bao , Anxo Perez , David Otero , Javier Parapar

Artificial intelligence (AI) has the potential to revolutionize the drug discovery process, offering improved efficiency, accuracy, and speed. However, the successful application of AI is dependent on the availability of high-quality data,…

Examining Drug-Drug Interactions (DDIs) is a pivotal element in the process of drug development. DDIs occur when one drug's properties are affected by the inclusion of other drugs. Detecting favorable DDIs has the potential to pave the way…

Machine Learning · Computer Science 2026-03-20 Azmine Toushik Wasi , Taki Hasan Rafi , Raima Islam , Serbetar Karlo , Dong-Kyu Chae

Since multidrug combination is widely applied, the accurate prediction of drug-drug interaction (DDI) is becoming more and more critical. In our method, we use graph to represent drug-drug interaction: nodes represent drug; edges represent…

Machine Learning · Computer Science 2022-09-01 Haifan zhou , Wenjing Zhou , Junfeng Wu

Adverse Drug Reactions (ADRs) are characterized within randomized clinical trials and postmarketing pharmacovigilance, but their molecular mechanism remains unknown in most cases. Aside from clinical trials, many elements of knowledge about…

Objective: To develop a corpus annotated for diet-microbiome associations from the biomedical literature and train natural language processing (NLP) models to identify these associations, thereby improving the understanding of their role in…

Computation and Language · Computer Science 2025-04-01 Gibong Hong , Veronica Hindle , Nadine M. Veasley , Hannah D. Holscher , Halil Kilicoglu

AI-powered scientific research tools are rapidly being integrated into research workflows, yet the field lacks a clear lens into how researchers use these systems in real-world settings. We present and analyze the Asta Interaction Dataset,…

With the emergence of deep learning techniques, smartphone apps are now embedded on-device AI features for enabling advanced tasks like speech translation, to attract users and increase market competitiveness. A good interaction design is…

Human-Computer Interaction · Computer Science 2023-07-04 Jason Ching Yuen Siu , Jieshan Chen , Yujin Huang , Zhenchang Xing , Chunyang Chen

The overwhelming amount of available scholarly literature in the life sciences poses significant challenges to scientists wishing to keep up with important developments related to their research, but also provides a useful resource for the…

Quantitative Methods · Quantitative Biology 2011-03-29 Huijun Wang , Ying Ding , Jie Tang , Xiao Dong , Bing He , Judy Qiu , David J. Wild

LLMs are popular among clinicians for decision-support because of simple text-based interaction. However, their impact on clinicians' performance is ambiguous. Not knowing how clinicians use this new technology and how they compare it to…

Human-Computer Interaction · Computer Science 2026-02-02 Behnam Rahdari , Sameer Shaikh , Jonathan H Chen , Tobias Gerstenberg , Shriti Raj

Drug-target interaction (DTI) prediction plays a very important role in drug development and drug discovery. Biochemical experiments or \textit{in vitro} methods are very expensive, laborious and time-consuming. Therefore, \textit{in…

Machine Learning · Computer Science 2018-05-04 Ratha Pech , Dong Hao , Yan-Li Lee , Maryna Po , Tao Zhou

In this work, we describe our team's approach to eRisk's 2025 Task 1: Search for Symptoms of Depression. Given a set of sentences and the Beck's Depression Inventory - II (BDI) questionnaire, participants were tasked with submitting up to…

Computation and Language · Computer Science 2025-06-04 Diogo A. P. Nunes , Eugénio Ribeiro

Detecting protein-protein interactions (PPIs) is crucial for understanding genetic mechanisms, disease pathogenesis, and drug design. However, with the fast-paced growth of biomedical literature, there is a growing need for automated and…

Computation and Language · Computer Science 2023-12-14 Hasin Rehana , Nur Bengisu Çam , Mert Basmaci , Jie Zheng , Christianah Jemiyo , Yongqun He , Arzucan Özgür , Junguk Hur

Cocaine addiction accounts for a large portion of substance use disorders and threatens millions of lives worldwide. There is an urgent need to come up with efficient anti-cocaine addiction drugs. Unfortunately, no medications have been…

Molecular Networks · Quantitative Biology 2021-09-21 Kaifu Gao , Dong Chen , Alfred J Robison , Guo-Wei Wei

Motivation: Protein-protein interactions (PPI) are critical to the function of proteins in both normal and diseased cells, and many critical protein functions are mediated by interactions.Knowledge of the nature of these interactions is…

Computation and Language · Computer Science 2022-01-10 Aparna Elangovan , Melissa Davis , Karin Verspoor

Identifying and discovering drug-target interactions(DTIs) are vital steps in drug discovery and development. They play a crucial role in assisting scientists in finding new drugs and accelerating the drug development process. Recently,…

Quantitative Methods · Quantitative Biology 2023-11-15 Wenting Ye , Chen Li , Yang Xie , Wen Zhang , Hong-Yu Zhang , Bowen Wang , Debo Cheng , Zaiwen Feng
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