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Purpose: To demonstrate that retinal microvasculature per se is a reliable biomarker for Diabetic Retinopathy (DR) and, by extension, cardiovascular diseases. Methods: Deep Learning Convolutional Neural Networks (CNN) applied to color…

Tissue characterization has long been an important component of Computer Aided Diagnosis (CAD) systems for automatic lesion detection and further clinical planning. Motivated by the superior performance of deep learning methods on various…

Deep Convolutional Neural Networks (CNNs) for image classification successively alternate convolutions and downsampling operations, such as pooling layers or strided convolutions, resulting in lower resolution features the deeper the…

Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…

Skin diseases affect over a third of the global population, yet their impact is often underestimated. Automating skin disease classification to assist doctors with their prognosis might be difficult. Nevertheless, due to efficient feature…

Early detection and accurate diagnosis can predict the risk of malignant disease transformation, thereby increasing the probability of effective treatment. Identifying mild syndrome with small pathological regions serves as an ominous…

Over 30 papers have proposed to use convolutional neural network (CNN) for AD classification from anatomical MRI. However, the classification performance is difficult to compare across studies due to variations in components such as…

Deep Learning (DL) approaches have been providing state-of-the-art performance in different modalities in the field of medical imagining including Digital Pathology Image Analysis (DPIA). Out of many different DL approaches, Deep…

We present a novel convolutional neural network (CNN) design for facial landmark coordinate regression. We examine the intermediate features of a standard CNN trained for landmark detection and show that features extracted from later, more…

Glaucoma is a major eye disease, leading to vision loss in the absence of proper medical treatment. Current diagnosis of glaucoma is performed by ophthalmologists who are often analyzing several types of medical images generated by…

Determining if the brain is developing normally is a key component of pediatric neuroradiology and neurology. Brain magnetic resonance imaging (MRI) of infants demonstrates a specific pattern of development beyond simply myelination. While…

Automated detection of cervical cancer cells or cell clumps has the potential to significantly reduce error rate and increase productivity in cervical cancer screening. However, most traditional methods rely on the success of accurate cell…

Background: Intracranial bleeding (IB) is a life-threatening condition caused by traumatic brain injuries, including epidural, subdural, subarachnoid, and intraparenchymal hemorrhages. Rapid and accurate detection is crucial to prevent…

Skin cancer is one of the most prevalent forms of human cancer. It is recognized mainly visually, beginning with clinical screening and continuing with the dermoscopic examination, histological assessment, and specimen collection. Deep…

In this paper, we introduce a deep learning model to classify children as either healthy or potentially autistic with 94.6% accuracy using Deep Learning. Autistic patients struggle with social skills, repetitive behaviors, and…

Convolutional neural networks (CNN) have become a powerful tool for detecting patterns in image data. Recent papers report promising results in the domain of disease detection using brain MRI data. Despite the high accuracy obtained from…

Retinal fundus images provide valuable insights into the human eye's interior structure and crucial features, such as blood vessels, optic disk, macula, and fovea. However, accurate segmentation of retinal blood vessels can be challenging…

Deep convolutional neural network (DCNN) models have been widely explored for skin disease diagnosis and some of them have achieved the diagnostic outcomes comparable or even superior to those of dermatologists. However, broad…

Lyme disease which is one of the most common infectious vector-borne diseases manifests itself in most cases with erythema migrans (EM) skin lesions. Recent studies show that convolutional neural networks (CNNs) perform well to identify…

Cerebrovascular accident, or commonly known as stroke, is an acute disease with extreme impact on patients and healthcare systems and is the second largest cause of death worldwide. Fast and precise stroke lesion detection and location is…