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Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

Biomolecules · Quantitative Biology 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

Large-scale sequential data is often exposed to some degree of inhomogeneity in the form of sudden changes in the parameters of the data-generating process. We consider the problem of detecting such structural changes in a high-dimensional…

Methodology · Statistics 2016-01-15 Florencia Leonardi , Peter Bühlmann

Autoregressive models are a class of generative model that probabilistically predict the next output of a sequence based on previous inputs. The autoregressive sequence is by definition one-dimensional (1D), which is natural for language…

Machine Learning · Computer Science 2024-08-29 Yi Hong Teoh , Roger G. Melko

We demonstrate the use of conditional autoregressive generative models (van den Oord et al., 2016a) over a discrete latent space (van den Oord et al., 2017b) for forward planning with MCTS. In order to test this method, we introduce a new…

Machine Learning · Computer Science 2018-11-27 Johanna Hansen , Kyle Kastner , Aaron Courville , Gregory Dudek

A characteristic of existing predictive process monitoring techniques is to first construct a predictive model based on past process executions, and then use it to predict the future of new ongoing cases, without the possibility of updating…

Artificial Intelligence · Computer Science 2023-10-26 Chiara Di Francescomarino , Chiara Ghidini , Fabrizio Maria Maggi , Williams Rizzi , Cosimo Damiano Persia

This paper develops algorithms for high-dimensional stochastic control problems based on deep learning and dynamic programming. Unlike classical approximate dynamic programming approaches, we first approximate the optimal policy by means of…

Probability · Mathematics 2021-09-21 Côme Huré , Huyên Pham , Achref Bachouch , Nicolas Langrené

We consider inference problems for high-dimensional (HD) functional data with a dense number (T) of repeated measurements taken for a large number of p variables from a small number of n experimental units. The spatial and temporal…

Methodology · Statistics 2020-05-06 Shawn Santo , Ping-Shou Zhong

Reinforcement learning algorithms rely on exploration to discover new behaviors, which is typically achieved by following a stochastic policy. In continuous control tasks, policies with a Gaussian distribution have been widely adopted.…

Machine Learning · Computer Science 2019-03-28 Dmytro Korenkevych , A. Rupam Mahmood , Gautham Vasan , James Bergstra

Diffusions are a successful technique to sample from high-dimensional distributions. The target distribution can be either explicitly given or learnt from a collection of samples. They implement a diffusion process whose endpoint is a…

Machine Learning · Computer Science 2025-09-03 Andrea Montanari

Evolutionary algorithms have been frequently used for dynamic optimization problems. With this paper, we contribute to the theoretical understanding of this research area. We present the first computational complexity analysis of…

Data Structures and Algorithms · Computer Science 2015-04-27 Frank Neumann , Carsten Witt

Stochastic resetting, the procedure of stopping and re-initializing random processes, has recently emerged as a powerful tool for accelerating processes ranging from queuing systems to molecular simulations. However, its usefulness is…

Statistical Mechanics · Physics 2025-03-18 Tommer D. Keidar , Ofir Blumer , Barak Hirshberg , Shlomi Reuveni

A key challenge in autoregressive image generation is to efficiently sample independent locations in parallel, while still modeling mutual dependencies with serial conditioning. Some recent works have addressed this by conditioning between…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 David Eigen

High-dimensional time series data appear in many scientific areas in the current data-rich environment. Analysis of such data poses new challenges to data analysts because of not only the complicated dynamic dependence between the series,…

Methodology · Statistics 2022-06-22 Di Wang , Ruey S. Tsay

High-dimensional changepoint analysis is a growing area of research and has applications in a wide range of fields. The aim is to accurately and efficiently detect changepoints in time series data when both the number of time points and…

Methodology · Statistics 2020-04-01 Thomas Grundy , Rebecca Killick , Gueorgui Mihaylov

Features in machine learning problems are often time-varying and may be related to outputs in an algebraic or dynamical manner. The dynamic nature of these machine learning problems renders current higher order accelerated gradient descent…

Optimization and Control · Mathematics 2019-05-29 Joseph E. Gaudio , Travis E. Gibson , Anuradha M. Annaswamy , Michael A. Bolender

Dynamic discrete choice models are widely employed to answer substantive and policy questions in settings where individuals' current choices have future implications. However, estimation of these models is often computationally intensive…

Methodology · Statistics 2025-04-11 Ebrahim Barzegary , Hema Yoganarasimhan

In high-dimensional time series, the component processes are often assembled into a matrix to display their interrelationship. We focus on detecting mean shifts with unknown change point locations in these matrix time series. Series that…

Methodology · Statistics 2024-07-16 Xinyu Zhang , Kung-Sik Chan

We present new algorithms and fast implementations to find efficient approximations for modelling stochastic processes. For many numerical computations it is essential to develop finite approximations for stochastic processes. While the…

Optimization and Control · Mathematics 2020-12-03 Kipngeno Benard Kirui , Georg Ch. Pflug , Alois Pichler

The problem of detecting the presence of a signal that can lead to a disaster is studied. A decision-maker collects data sequentially over time. At some point in time, called the change point, the distribution of data changes. This change…

Signal Processing · Electrical Eng. & Systems 2023-03-07 Tim Brucks , Taposh Banerjee , Rahul Mishra

Recent advances in local models for point processes have highlighted the need for flexible methodologies to account for the spatial heterogeneity of external covariates influencing process intensity. In this work, we introduce tessellated…

Methodology · Statistics 2025-04-11 Nicoletta D'Angelo