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Hydrophobic molecules such as oils and certain drugs can be encapsulated between the two leaflets of an amphiphilic bilayer in both lipid and polymer systems. We investigate the case where the hydrophobic molecules are incompatible with the…

Soft Condensed Matter · Physics 2012-07-02 M. J. Greenall , C. M. Marques

Amphiphilic polymers in aqueous solutions can self-assemble to form bilayer membranes, and their elastic properties can be captured by the well-known Helfrich model involving several elastic constants. In this paper, we employ the…

Soft Condensed Matter · Physics 2024-03-06 Yongshun Luo , Min Yang , Sirui Li , Yana Di , Yongqiang Cai

We present a simple and computationally efficient coarse-grained and solvent-free model for simulating lipid bilayer membranes. In order to be used in concert with particle-based reaction-diffusion simulations, the model is purely based on…

Biological Physics · Physics 2018-01-31 Mohsen Sadeghi , Thomas R. Weikl , Frank Noé

Detailed understanding of the coupling between fluid flow and solid deformation in porous media is crucial for the development biomedical devices and novel energy technologies relating to a wide range of geological and biological processes.…

Fluid Dynamics · Physics 2021-09-22 Francisco J. Carrillo

Emergent phenomena share the fascinating property of not being obvious consequences of the design of the system in which they appear. This characteristic is no less relevant when attempting to simulate such phenomena, given that the outcome…

Soft Condensed Matter · Physics 2014-11-26 D. C. Rapaport

Certain sequences of peptoid polymers (synthetic analogs of peptides) assemble into bilayer nanosheets via a nonequilibrium assembly pathway of adsorption, compression, and collapse at an air-water interface. As with other large-scale…

Biological Physics · Physics 2014-10-01 Thomas K. Haxton , Ranjan V. Mannige , Ronald N. Zuckermann , Stephen Whitelam

We review recent molecular dynamics simulations of thermally activated undulations and defects in the lamellar $L_\alpha$ phase of a binary amphiphile-solvent mixture, using an idealized molecular coarse-grained model: Solvent particles are…

Soft Condensed Matter · Physics 2009-11-11 Claire Loison , Michel Mareschal , Friederike Schmid

A minimalist simulation model for lipid bilayers is presented. Each lipid is represented by a flexible chain of beads in implicit solvent. The hydrophobic effect is mimicked through an intermolecular pair potential localized at the…

Statistical Mechanics · Physics 2009-11-11 Grace Brannigan , Peter F. Philips , Frank L. H. Brown

We present a model for the joint self-assembly of amphiphilic polymers and small amphiphilic molecules (surfactants) in a dilute aqueous solution. The polymer is assumed to consist of a hydrophilic backbone and a large number of hydrophobic…

Soft Condensed Matter · Physics 2007-05-23 H. Diamant , D. Andelman

Magnetic nanoparticles in a colloidal solution self-assemble in various aligned structures, which has a profound influence on the flow behavior. However, the precise role of the microstructure in the development of the rheological response…

Soft Condensed Matter · Physics 2017-04-25 Dmitry Zablotsky , Elmars Blums , Hans J. Herrmann

A soft particle model for diblock (AB) copolymer melts is proposed. Each molecule is mapped onto two soft spheres built by Gaussian A- and B-monomer distributions. An approximate analytical expression for the joint distribution function for…

Materials Science · Physics 2009-11-13 F. Eurich , A. Karatchentsev , J. Baschnagel , W. Dieterich , P. Maass

In this paper, we first develop a mathematical model for long-range, hydrophobic attraction between amphiphilic particles. The non-pairwise interactions follow from the first variation of a hydrophobic attraction domain functional. The…

Numerical Analysis · Mathematics 2019-07-19 Szu-Pei P. Fu , Rolf J. Ryham , Andreas Klöckner , Matt Wala , Shidong Jiang , Yuan-Nan Young

We systematically explore the self-assembly of semi-flexible polymers in deformable spherical confinement across a wide regime of chain stiffness, contour lengths and packing fractions by means of coarse-grained molecular dynamics…

Soft Condensed Matter · Physics 2021-07-12 Maxime M. C. Tortora , Daniel Jost

We present an extensive computer simulation study of structure formation in amphiphilic block copolymer solutions after a quench from a homogeneous state. By using a mesoscopic field-based simulation method, we are able to access time…

Soft Condensed Matter · Physics 2009-11-13 Xuehao He , Friederike Schmid

The elastic property of membranes self-assembled from AB diblock and ABA triblock copolymers, as coarse-grained model of lipids and the bolalipids, are studied using the self-consistent field theory (SCFT). Specifically, solutions of the…

Soft Condensed Matter · Physics 2019-05-17 Rui Xu , Ashkan Dehghan , An-Chang Shi , Jiajia Zhou

The phase behaviour of amphiphilic multiblock copolymers with a large number of blocks in semidilute solutions is studied by lattice Monte Carlo simulations. The influence on the resulting structures of the concentration, the solvent…

Soft Condensed Matter · Physics 2016-08-18 Virginie Hugouvieux , Monique A. V. Axelos , Max Kolb

Force field have for decades proven to be an indispensable tool for molecular simulations which are out of reach for ab-initio methods. Recent efforts to improve the accuracy of these simulations have focused on the inclusion of many-body…

Chemical Physics · Physics 2020-06-26 Ruben Goeminne , Toon Verstraelen

Soft particles display highly versatile properties with respect to hard colloids, even more so at fluid-fluid interfaces. In particular, microgels, consisting of a cross-linked polymer network, are able to deform and flatten upon adsorption…

During the early-stages of embryo development, morphogenesis--- the emergence of shape and form in living organisms--- is almost exclusively associated with monolayers of tightly bound epithelial cells. To understand how such tissues change…

Soft Condensed Matter · Physics 2019-08-28 Richard G. Morris , Madan Rao

Morphological transformations of amphiphilic AB diblock copolymers in mixtures of a common solvent (S1) and a selective solvent (S2) for the B block are studied using the simulated annealing method. We focus on the morphological…

Soft Condensed Matter · Physics 2017-03-28 Zheng Wang , Yuhua Yin , Run Jiang , Baohui Li