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This study investigates a 3D and fully convolutional neural network (CNN) for subcortical brain structure segmentation in MRI. 3D CNN architectures have been generally avoided due to their computational and memory requirements during…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 J. Dolz , C. Desrosiers , I. Ben Ayed

Microscopy structure segmentation, such as detecting cells or nuclei, generally requires a human to draw a ground truth contour around each instance. Weakly supervised approaches (e.g. consisting of only single point labels) have the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 James Willoughby , Irina Voiculescu

With a large influx of dermoscopy images and a growing shortage of dermatologists, automatic dermoscopic image analysis plays an essential role in skin cancer diagnosis. In this paper, a new deep fully convolutional neural network (FCNN) is…

Computer Vision and Pattern Recognition · Computer Science 2017-03-17 Jin Qi , Miao Le , Chunming Li , Ping Zhou

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Fluorescent Neuronal Cells v2 is a collection of fluorescence microscopy images and the corresponding ground-truth annotations, designed to foster innovative research in the domains of Life Sciences and Deep Learning. This dataset…

We propose a software platform that integrates methods and tools for multi-objective parameter auto- tuning in tissue image segmentation workflows. The goal of our work is to provide an approach for improving the accuracy of nucleus/cell…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-09 Luis F. R. Taveira , Tahsin Kurc , Alba C. M. A. Melo , Jun Kong , Erich Bremer , Joel H. Saltz , George Teodoro

We have developed an automatic method for segmenting fluorescence lifetime (FLT) imaging microscopy (FLIM) images of cells inspired by a multi-resolution community detection (MCD) based network segmentation method. The image processing…

Medical Physics · Physics 2014-01-06 Dandan Hu , Pinaki Sarder , Peter Ronhovde , Sandra Orthaus , Samuel Achilefu , Zohar Nussinov

Fully convolutional networks (FCNs), including UNet and VNet, are widely-used network architectures for semantic segmentation in recent studies. However, conventional FCN is typically trained by the cross-entropy or Dice loss, which only…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Kelei He , Chunfeng Lian , Ehsan Adeli , Jing Huo , Yang Gao , Bing Zhang , Junfeng Zhang , Dinggang Shen

In this work we propose a novel approach to perform segmentation by leveraging the abstraction capabilities of convolutional neural networks (CNNs). Our method is based on Hough voting, a strategy that allows for fully automatic…

Motivation: 3D neuron segmentation is a key step for the neuron digital reconstruction, which is essential for exploring brain circuits and understanding brain functions. However, the fine line-shaped nerve fibers of neuron could spread in…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Qiufu Li , Linlin Shen

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

Quantitative Methods · Quantitative Biology 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi

Accurate segmentation for medical images is important for clinical diagnosis. Existing automatic segmentation methods are mainly based on fully supervised learning and have an extremely high demand for precise annotations, which are very…

Computer Vision and Pattern Recognition · Computer Science 2021-06-10 Yuanpeng Liu , Qinglei Hui , Zhiyi Peng , Shaolin Gong , Dexing Kong

Early diagnosis is essential for the successful treatment of bowel cancers including colorectal cancer (CRC) and capsule endoscopic imaging with robotic actuation can be a valuable diagnostic tool when combined with automated image…

Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Zunaira Rauf , Abdul Rehman Khan , Asifullah Khan

Contemporary approaches to instance segmentation in cell science use 2D or 3D convolutional networks depending on the experiment and data structures. However, limitations in microscopy systems or efforts to prevent phototoxicity commonly…

Computer Vision and Pattern Recognition · Computer Science 2023-01-27 Christopher Z. Eddy , Austin Naylor , Bo Sun

We propose an unsupervised superpixel segmentation method by optimizing a randomly-initialized convolutional neural network (CNN) in inference time. Our method generates superpixels via CNN from a single image without any labels by…

Computer Vision and Pattern Recognition · Computer Science 2020-06-29 Teppei Suzuki

This paper presents a method for text line segmentation of challenging historical manuscript images. These manuscript images contain narrow interline spaces with touching components, interpenetrating vowel signs and inconsistent font types…

Computer Vision and Pattern Recognition · Computer Science 2021-01-22 Berat Barakat , Ahmad Droby , Majeed Kassis , Jihad El-Sana

Typical convolutional neural networks (CNNs) have several millions of parameters and require a large amount of annotated data to train them. In medical applications where training data is hard to come by, these sophisticated machine…

Computer Vision and Pattern Recognition · Computer Science 2016-12-09 Rahul Venkataramani , Sheshadri Thiruvenkadam , Prasad Sudhakar , Hariharan Ravishankar , Vivek Vaidya