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In the context of Multi Instance Learning, we analyze the Single Instance (SI) learning objective. We show that when the data is unbalanced and the family of classifiers is sufficiently rich, the SI method is a useful learning algorithm. In…

Machine Learning · Computer Science 2018-12-19 Mark Kozdoba , Edward Moroshko , Lior Shani , Takuya Takagi , Takashi Katoh , Shie Mannor , Koby Crammer

Multiple instance learning (MIL) is an effective and widely used approach for weakly supervised machine learning. In histopathology, MIL models have achieved remarkable success in tasks like tumor detection, biomarker prediction, and…

Multiple instance learning (MIL) aims to learn the mapping between a bag of instances and the bag-level label. In this paper, we propose a new end-to-end graph neural network (GNN) based algorithm for MIL: we treat each bag as a graph and…

Machine Learning · Computer Science 2019-06-13 Ming Tu , Jing Huang , Xiaodong He , Bowen Zhou

We introduce a graphical framework for multiple instance learning (MIL) based on Markov networks. This framework can be used to model the traditional MIL definition as well as more general MIL definitions. Different levels of ambiguity --…

Machine Learning · Computer Science 2013-09-27 Hossein Hajimirsadeghi , Jinling Li , Greg Mori , Mohammad Zaki , Tarek Sayed

Multiple instance learning (MIL) was a weakly supervised learning approach that sought to assign binary class labels to collections of instances known as bags. However, due to their weak supervision nature, the MIL methods were susceptible…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Wenhui Zhu , Peijie Qiu , Xiwen Chen , Oana M. Dumitrascu , Yalin Wang

We propose a novel framework to classify large-scale time series data with long duration. Long time seriesclassification (L-TSC) is a challenging problem because the dataoften contains a large amount of irrelevant information to…

Artificial Intelligence · Computer Science 2021-11-23 Yuansheng Zhu , Weishi Shi , Deep Shankar Pandey , Yang Liu , Xiaofan Que , Daniel E. Krutz , Qi Yu

Multiple Instance Learning (MIL) has been widely applied to medical imaging diagnosis, where bag labels are known and instance labels inside bags are unknown. Traditional MIL assumes that instances in each bag are independent samples from a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Yunan Wu , Francisco M. Castro-Macías , Pablo Morales-Álvarez , Rafael Molina , Aggelos K. Katsaggelos

Despite the tremendous advances in machine learning (ML), training with imbalanced data still poses challenges in many real-world applications. Among a series of diverse techniques to solve this problem, sampling algorithms are regarded as…

Machine Learning · Computer Science 2024-04-19 Angelos Chatzimparmpas , Fernando V. Paulovich , Andreas Kerren

Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Daniel Shao , Richard J. Chen , Andrew H. Song , Joel Runevic , Ming Y. Lu , Tong Ding , Faisal Mahmood

By allowing models to predict without task-specific training, in-context learning (ICL) with pretrained LLMs has enormous potential in NLP. However, a number of problems persist in ICL. In particular, its performance is sensitive to the…

Computation and Language · Computer Science 2024-02-20 Zhichao Xu , Daniel Cohen , Bei Wang , Vivek Srikumar

In this paper, we investigate the multi-variate sequence classification problem from a multi-instance learning perspective. Real-world sequential data commonly show discriminative patterns only at specific time periods. For instance, we can…

Machine Learning · Computer Science 2017-12-21 Xiaowei Jia , Ankush Khandelwal , Anuj Karpatne , Vipin Kumar

Learning from Label Proportions (LLP) is a weakly supervised learning method that aims to perform instance classification from training data consisting of pairs of bags containing multiple instances and the class label proportions within…

Machine Learning · Computer Science 2023-02-22 Ryoma Kobayashi , Yusuke Mukuta , Tatsuya Harada

In statistical learning, many problem formulations have been proposed so far, such as multi-class learning, complementarily labeled learning, multi-label learning, multi-task learning, which provide theoretical models for various real-world…

Machine Learning · Computer Science 2022-11-14 Daiki Suehiro , Eiji Takimoto

In-line with the success of deep learning on traditional recognition problem, several end-to-end deep models for zero-shot recognition have been proposed in the literature. These models are successful to predict a single unseen label given…

Computer Vision and Pattern Recognition · Computer Science 2018-03-19 Shafin Rahman , Salman Khan

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

Multiple instance learning (MIL) significantly reduced annotation costs via bag-level weak labels for large-scale images, such as histopathological whole slide images (WSIs). However, its adaptability to continual tasks with minimal…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Byung Hyun Lee , Wongi Jeong , Woojae Han , Kyoungbun Lee , Se Young Chun

In this paper, we present a new multiple instance learning (MIL) method, called MIS-Boost, which learns discriminative instance prototypes by explicit instance selection in a boosting framework. Unlike previous instance selection based MIL…

Machine Learning · Computer Science 2011-09-13 Emre Akbas , Bernard Ghanem , Narendra Ahuja

We propose an alternative method for training a classification model. Using the MNIST set of handwritten digits and Restricted Boltzmann Machines, it is possible to reach a classification performance competitive to semi-supervised learning…

Machine Learning · Computer Science 2015-09-04 Malte Probst , Franz Rothlauf

We present a comprehensive study of the use of generative modeling approaches for Multiple-Instance Learning (MIL) problems. In MIL a learner receives training instances grouped together into bags with labels for the bags only (which might…

Machine Learning · Computer Science 2013-09-27 Tameem Adel , Benn Smith , Ruth Urner , Daniel Stashuk , Daniel J. Lizotte

Multiple Instance Learning (MIL) is a popular weakly-supervised method for various applications, with a particular interest in histological whole slide image (WSI) classification. Due to the gigapixel resolution of WSI, applications of MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Wenhui Zhu , Peijie Qiu , Xiwen Chen , Zhangsihao Yang , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang
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