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We propose a new compression scheme for genomic data given as sequence fragments called reads. The scheme uses a reference genome at the decoder side only, freeing the encoder from the burdens of storing references and performing…

Information Theory · Computer Science 2023-02-10 Yotam Gershon , Yuval Cassuto

Computing the similarity between two DNA sequences is of vital importance in bioscience, yet it can be computationally expensive on classical hardware. For example, the edit distance with move operations (EDM), a DNA similarity measure of…

Quantum Physics · Physics 2025-12-03 Chenyu Shi , Gabriele Leoni , Mauro Petrillo , Antonio Puertas Gallardo , Hao Wang

Grover search is a renowned quantum search algorithm that leverages quantum superposition to find a marked item with quadratic speedup. However, when implemented on Noisy Intermediate-scale Quantum (NISQ) hardware, the required repeated…

Quantum Physics · Physics 2023-04-11 Chen-Yu Liu

As edge applications using convolutional neural networks (CNN) models grow, it is becoming necessary to introduce dedicated hardware accelerators in which network parameters and feature-map data are represented with limited precision. In…

Neural and Evolutionary Computing · Computer Science 2018-11-01 Doyun Kim , Han Young Yim , Sanghyuck Ha , Changgwun Lee , Inyup Kang

Grover's unstructured search algorithm is one of the best examples to date for the superiority of quantum algorithms over classical ones. Its applicability, however, has been questioned by many due to its oracular nature. We propose a…

Quantum Physics · Physics 2017-08-21 Itay Hen

Quantum adiabatic optimization seeks to solve combinatorial problems using quantum dynamics, requiring the Hamiltonian of the system to align with the problem of interest. However, these Hamiltonians are often incompatible with the native…

We present a computational method to automatically design the n-qubit realisations of quantum algorithms. Our approach leverages a domain-specific language (DSL) that enables the construction of quantum circuits via modular building blocks,…

Quantum Physics · Physics 2025-11-14 Amy Rouillard , Matt Lourens , Francesco Petruccione

Molecular docking (MD) is a crucial task in drug design, which predicts the position, orientation, and conformation of the ligand when bound to a target protein. It can be interpreted as a combinatorial optimization problem, where quantum…

Chemical Physics · Physics 2024-04-15 Yunting Li , Xiaopeng Cui , Zhaoping Xiong , Bowen Liu , Bi-Ying Wang , Runqiu Shu , Nan Qiao , Man-Hong Yung

In this paper, we explore the power of Quantum Machine Learning as we extend, implement and evaluate algorithms like Quantum Support Vector Classifier (QSVC), Pegasos-QSVC, Variational Quantum Circuits (VQC), and Quantum Neural Networks…

Machine Learning · Computer Science 2024-05-17 Navneet Singh , Shiva Raj Pokhrel

We investigate the implementation of an oracle for the Subset Sum problem for quantum search using Grover's algorithm. Our work concerns reducing the number of qubits, gates, and multi-controlled gates required by the oracle. We describe…

Emerging Technologies · Computer Science 2024-10-03 Angelo Benoit , Sam Schwartz , Ron K. Cytron

Quantum computing has shown theoretical promise of speedup in several machine learning tasks, including generative tasks using generative adversarial networks (GANs). While quantum computers have been implemented with different types of…

Quantum Physics · Physics 2024-10-11 Nicholas S. DiBrita , Daniel Leeds , Yuqian Huo , Jason Ludmir , Tirthak Patel

Calculating the similarities between a pair of genomic sequences is one of the most fundamental computational steps in genomic analysis. This step -- called sequence alignment -- is the computational bottleneck because: (1) it is…

Genomics · Quantitative Biology 2019-10-10 Mohammed H K Alser

Recent advances in the fields of deep learning and quantum computing have paved the way for innovative developments in artificial intelligence. In this manuscript, we leverage these cutting-edge technologies to introduce a novel model that…

Emerging Technologies · Computer Science 2025-05-06 Eva Andrés , Manuel Pegalajar Cuéllar , Gabriel Navarro

The Grover algorithm is a crucial solution for addressing unstructured search problems and has emerged as an essential quantum subroutine in various complex algorithms. By using a different approach with previous studies, this research…

Quantum Physics · Physics 2024-12-04 Yifan Sun , Lian-Ao Wu

Quantum architecture search (QAS) is desired to construct a powerful and general QAS platform which can significantly accelerate quantum advantages in error-prone and depth limited quantum circuits in today Noisy Intermediate-Scale Quantum…

Quantum Physics · Physics 2022-12-02 Anqi Zhang , Shengmei Zhao

In this work, we present a quantum query algorithm for searching a word of length $m$ in an unsorted dictionary of size $n$. The algorithm uses $O(\sqrt{n})$ queries (Grover operators), like previously known algorithms. What is new is that…

Quantum Physics · Physics 2024-12-17 Farid Ablayev , Nailya Salikhova , Marat Ablayev

We consider the problem of search of an unstructured list for a marked element, when one is given advice as to where this element might be located, in the form of a probability distribution. The goal is to minimise the expected number of…

Quantum Physics · Physics 2012-08-02 Ashley Montanaro

Background: Solving nuclear many-body problems with an ab initio approach is widely recognized as a computationally challenging problem. Quantum computers offer a promising path to address this challenge. There are urgent needs to develop…

Nuclear Theory · Physics 2021-05-20 Weijie Du , James P. Vary , Xingbo Zhao , Wei Zuo

Negative Selection Algorithms (NSAs), inspired by the self/non-self discrimination mechanism of the human immune system, have been widely employed in anomaly detection. However, their effectiveness is often constrained by the efficiency of…

Neural and Evolutionary Computing · Computer Science 2026-05-22 Giancarlo P. Gamberi , Calebe P. Bianchini

In this paper we present an architecture that enables the redesign of large-scale quantum circuits on quantum hardware based on the entangling quantum generative adversarial network (EQ-GAN). Specifically, by prepending a random quantum…

Quantum Physics · Physics 2025-05-19 Runhong He , Ji Guan , Xin Hong , Guolong Cui , Shengbin Wang , Shenggang Ying
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