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Modern 3D Computer-Aided-Design (CAD) systems use mainly two types of geometric models. Classically, objects are defined by a Boundary Representation (B-Rep), where only the objects' surfaces with their corresponding edges and nodes are…

Computational Engineering, Finance, and Science · Computer Science 2018-09-27 Benjamin Wassermann , Tino Bog , Stefan Kollmannsberger , Ernst Rank

This paper introduces the methodology proposed by our group to model the biological soft tissues deformations and to couple these models with Computer-Assisted Surgical (CAS) applications. After designing CAS protocols that mainly focused…

Recent advances in molecular generative models have demonstrated great promise for accelerating scientific discovery, particularly in drug design. However, these models often struggle to generate high-quality molecules, especially in…

Machine Learning · Computer Science 2025-07-29 Zian Li , Cai Zhou , Xiyuan Wang , Xingang Peng , Muhan Zhang

Variable-density cellular structures can overcome connectivity and manufacturability issues of topologically optimized structures, particularly those represented as discrete density maps. However, the optimization of such cellular…

Computational Engineering, Finance, and Science · Computer Science 2022-06-08 Jun Wang , Wei Wayne Chen , Daicong Da , Mark Fuge , Rahul Rai

Creating CAD digital twins from the physical world is crucial for manufacturing, design, and simulation. However, current methods typically rely on costly 3D scanning with labor-intensive post-processing. To provide a user-friendly design…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Cheng Chen , Jiacheng Wei , Tianrun Chen , Chi Zhang , Xiaofeng Yang , Shangzhan Zhang , Bingchen Yang , Chuan-Sheng Foo , Guosheng Lin , Qixing Huang , Fayao Liu

In this work, we introduce a novel computational framework that we developed to use numerical simulations to investigate the complexity of brain tissue at a microscopic level with a detail never realised before. Directly inspired by the…

Medical Physics · Physics 2018-06-20 Marco Palombo , Daniel C. Alexander , Hui Zhang

The optimal use of resources has motivated the engineering community to employ controlled distribution of material within their structural designs, often relying on cellular and lattice porous structures. In this research work, a…

Materials Science · Physics 2022-07-15 A. E Gomez-Ovalle

A three-dimensional, parallelized implementation of the electromagnetic relativistic moment implicit particle-in-cell method in Cartesian geometry (Noguchi et. al., 2007) is presented. Particular care was taken to keep the C++11 codebase…

Computational Physics · Physics 2015-01-08 Andreas Kempf , Patrick Kilian , Urs Ganse , Cedric Schreiner , Felix Spanier

We present a probabilistic 3D generative model, named Generative Cellular Automata, which is able to produce diverse and high quality shapes. We formulate the shape generation process as sampling from the transition kernel of a Markov…

Computer Vision and Pattern Recognition · Computer Science 2021-03-09 Dongsu Zhang , Changwoon Choi , Jeonghwan Kim , Young Min Kim

This chapter provides a brief introduction to the theory and practice of spatial stochastic simulations. It begins with an overview of different methods available for biochemical simulations highlighting their strengths and limitations.…

Quantitative Methods · Quantitative Biology 2018-10-02 Sanjana Gupta , Jacob Czech , Robert Kuczewski , Thomas M. Bartol , Terrence J. Sejnowski , Robin E. C. Lee , James R. Faeder

3D Gaussian Splatting (3DGS) has enabled high-fidelity virtualization with fast rendering and optimization for novel view synthesis. On the other hand, triangle mesh models still remain a popular choice for surface reconstruction but suffer…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Xinpeng Liu , Fumio Okura

We present the newly developed code, GAMER (GPU-accelerated Adaptive MEsh Refinement code), which has adopted a novel approach to improve the performance of adaptive mesh refinement (AMR) astrophysical simulations by a large factor with the…

Instrumentation and Methods for Astrophysics · Physics 2010-02-08 Hsi-Yu Schive , Yu-Chih Tsai , Tzihong Chiueh

We present TriMe++, a multi-threaded software library designed for generating two-dimensional meshes for intricate geometric shapes using the Delaunay triangulation. Multi-threaded parallel computing is implemented throughout the meshing…

Computational Geometry · Computer Science 2024-12-10 Jiayin Lu , Chris H. Rycroft

Continuum or hybrid modeling of bilayer membrane morphological dynamics induced by embedded proteins necessitates the identification of protein-membrane interfaces and coupling of deformations of two surfaces. In this article we developed…

Soft Condensed Matter · Physics 2020-06-29 Y. C. Zhou , David Argudo , Frank Marcoline , Michael Grabe

Deep learning based 3D shape generation methods generally utilize latent features extracted from color images to encode the semantics of objects and guide the shape generation process. These color image semantics only implicitly encode 3D…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Rakesh Shrestha , Zhiwen Fan , Qingkun Su , Zuozhuo Dai , Siyu Zhu , Ping Tan

In this work, we review previously developed coarse-grained (CG) particle models for biological membrane and red blood cells (RBCs) and discuss the advantages of the CG particle method over the continuum and atomic simulations on modeling…

Soft Condensed Matter · Physics 2017-07-18 He Li , Hung-yu Chang , Jun Yang , Lu Lu , George Lykotrafitis

Detailed radiation analysis of instruments flown in space is critical to ensure mission safety, often requiring the use of state-of-the-art particle transport simulation tools. Geant4 is one of the most powerful toolkits to simulate the…

Computational Physics · Physics 2019-03-29 Marco Pinto , Patrícia Gonçalves

Anatomy evaluation is crucial for understanding the physiological state, diagnosing abnormalities, and guiding medical interventions. Statistical shape modeling (SSM) is vital in this process. By enabling the extraction of quantitative…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Krithika Iyer , Mokshagna Sai Teja Karanam , Shireen Elhabian

We present a deep learning model to automatically generate computer models of the human heart from patient imaging data with an emphasis on its capability to generate thin-walled cardiac structures. Our method works by deforming a template…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Arjun Narayanan , Fanwei Kong , Shawn Shadden

Meshes serve as a primary representation for 3D assets. Autoregressive mesh generators serialize faces into sequences and train on truncated segments with sliding-window inference to cope with memory limits. However, this mismatch breaks…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Junkai Lin , Hang Long , Huipeng Guo , Jielei Zhang , JiaYi Yang , Tianle Guo , Yang Yang , Jianwen Li , Wenxiao Zhang , Matthias Nießner , Wei Yang