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The curtain of technical limitations impeding rat multichannel non-invasive electroencephalography (EEG) has risen. Given the importance of this preclinical model, development and validation of EEG source imaging (ESI) is essential. We…

Neurons and Cognition · Quantitative Biology 2016-01-26 Pedro A. Valdes-Hernandez , Jihye Bae , Yinchen Song , Akira Sumiyoshi , Eduardo Aubert-Vazquez , Jorge J. Riera

Identifying cortical regions critical for speech is essential for safe brain surgery in or near language areas. While Electrical Stimulation Mapping (ESM) remains the clinical gold standard, it is invasive and time-consuming. To address…

Transcranial magnetic stimulation (TMS) is widely used for understanding brain function in neurologically intact subjects and for the treatment of various disorders. However, the precise neurophysiological effects of TMS at the site of…

Neurons and Cognition · Quantitative Biology 2021-10-27 Farshad Rafiei , Dobromir Rahnev

As a class of electron-rich materials, electrides demonstrate promising applications in many fields. However, the required high pressure restricts the practical applications to some extent. This study reveals that the unique feature of…

Materials Science · Physics 2025-12-03 L. Zhang , D. Wang , H. Wang , J. Li , Y. F. Wang , Q. Wu , Hua Y. Geng

Background. Neuromodulation by electrical stimulation of the human cervical vagus nerve may be limited by adverse side effects due to stimulation of off-target organs. It may be possible to overcome this by spatially selective stimulation…

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a multitude of neurological and neuropsychiatric disorders. At the single-patient level, however, symptoms may sometimes persist despite "optimal"…

Electroencephalography (EEG) is a widely used non-invasive technique for measuring brain activity in brain-computer interface (BCI) applications. Supervised EEG decoding models often struggle to generalize across tasks, subjects, and…

Artificial Intelligence · Computer Science 2026-05-29 Ayse Betul Yuce , Sebastian Stober

Predicting post-operative seizure freedom using functional correlation networks derived from interictal intracranial EEG has shown some success. However, there are important challenges to consider. 1: electrodes physically closer to each…

Deep Brain Stimulation (DBS) is a well-established neurosurgical treatment aiming at symptom alleviation in a range of neurological and psychiatric diseases. Computational models of DBS are widely used to investigate the effects of…

Systems and Control · Electrical Eng. & Systems 2025-11-17 Anna Franziska Frigge , Alexander Medvedev

We present an error-controlled mesh refinement procedure for needle insertion simulation and apply it to the simulation of electrode implantation for deep brain stimulation, including brain shift. Our approach enables to control the error…

Computational Engineering, Finance, and Science · Computer Science 2018-11-20 Huu Phuoc Bui , Satyendra Tomar , Hadrien Courtecuisse , Michel Audette , Stéphane Cotin , Stéphane P. A. Bordas

Functional connectivity (FC) between brain regions tracks symptom severity in many neuropsychiatric disorders. Transcranial magnetic stimulation (TMS) directly alters regional activity and indirectly alters FC. Predicting how FC will change…

Neurons and Cognition · Quantitative Biology 2022-08-25 Andrew C. Murphy , Romain Duprat , Theodore D. Satterthwaite , Desmond J. Oathes , Dani S. Bassett

Transcranial magnetic stimulation combined with electroencephalography (TMS-EEG) is widely used to study the reactivity and connectivity of brain regions for clinical or research purposes. The electromagnetic pulse of the TMS device…

Quantitative Methods · Quantitative Biology 2019-10-30 Panteleimon Vafeidis , Vasilios K. Kimiskidis , Dimitris Kugiumtzis

In this article we present the results of our research related to the study of correlations between specific visual stimulation and the elicited brain's electro-physiological response collected by EEG sensors from a group of participants.…

Machine Learning · Computer Science 2017-08-04 Iaroslav Omelianenko

Current steering on a multi-electrode array is commonly used to shape the electric field in the neural tissue in order to improve selectivity and efficacy of stimulation. Previously, simulations of the electric field in tissue required…

Biological Physics · Physics 2020-12-29 Zhijie Charles Chen , Bing-Yi Wang , Daniel Palanker

Localizing neuronal activity in the brain, both in time and in space, is a central challenge to advance the understanding of brain function. Because of the inability of any single neuroimaging techniques to cover all aspects at once, there…

Neurons and Cognition · Quantitative Biology 2013-07-09 Yaroslav O. Halchenko , Michael Hanke , James V. Haxby , Stephen Jose Hanson , Christoph S. Herrmann

Cortical visual prostheses aim to restore sight by electrically stimulating neurons in early visual cortex (V1). With the emergence of high-density and flexible neural interfaces, electrode placement within three-dimensional cortex has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Galen Pogoncheff , Alvin Wang , Jacob Granley , Michael Beyeler

Bioelectric source analysis in the human brain from scalp electroencephalography (EEG) signals is sensitive to the conductivity of the different head tissues. Conductivity values are subject dependent, so non-invasive methods for…

Computational Engineering, Finance, and Science · Computer Science 2019-08-30 Kostiantyn Maksymenko , Maureen Clerc , Théodore Papadopoulo

Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human neuromodulation, with a pressing need to establish protocols that maximise neuromodulatory efficacy. In this review, we aggregate and examine…

Biological Physics · Physics 2024-07-04 Tulika Nandi , Benjamin R. Kop , Kim Butts Pauly , Charlotte J. Stagg , Lennart Verhagen

Recent advancements in neurotechnology enable precise spatiotemporal patterns of microstimulations with single-cell resolution. The choice of perturbation sites must satisfy two key criteria: efficacy in evoking significant responses and…

Neurons and Cognition · Quantitative Biology 2025-06-02 Anandita De , Roozbeh Kiani , Luca Mazzucato

High temporal resolution measurements of human brain activity can be performed by recording the electric potentials on the scalp surface (electroencephalography, EEG), or by recording the magnetic fields near the surface of the head…

Data Analysis, Statistics and Probability · Physics 2015-01-22 Kevin H. Knuth
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