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In this work, we continue the modelling of the digestion in the small intestine, started in a previous article, by investigating the effects of dietary fibre. We recall that this model aims at taking into account the three main phenomena of…
Recent studies show that the microbial communities inhabiting the human intestine can have profound impact on our well-being and health. However, we have limited understanding of the mechanisms that control this complex ecosystem. Based on…
Communication and coordination play a major role in the ability of bacterial cells to adapt to ever changing environments and conditions. Recent work has shown that such coordination underlies several aspects of bacterial responses…
Digital life, a form of life generated by computer programs or artificial intelligence systems, it possesses self-awareness, thinking abilities, emotions, and subjective consciousness. Achieving it involves complex neural networks,…
Discrete-time models are the traditional approach for capturing population dynamics of a host-parasitoid system. Recent work has introduced a semi-discrete framework for obtaining model update functions that connect host-parasitoid…
The impact of digital device use on health and well-being is a pressing question to which individuals, families, schools, policy makers, legislators, and digital designers are all demanding answers. However, the scientific literature on…
Globalization has fundamentally reshaped societal dynamics, influencing how individuals interact and perceive themselves and others. One significant consequence is the evolving landscape of eating disorders such as bulimia nervosa (BN),…
Biological systems are promising substrates for computation because they naturally process environmental information through complex internal dynamics. In this study, we investigate whether bacterial metabolic models can act as physical…
The human microbiome is a complex ecological system, and describing its structure and function under different environmental conditions is important from both basic scientific and medical perspectives. Viewed through a biostatistical lens,…
The human gut microbiota is a complex ecosystem that affects a range of human physiology. In order to explore the dynamics of the human gut microbiota, we used a system of ordinary differential equations to model mathematically the biomass…
Crohn's disease (CD) is associated with an ecological imbalance of the intestinal microbiota, consisting of hundreds of species. The underlying complexity as well as individual differences between patients contributes to the difficulty to…
A primary motivation for our research in digital ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…
There has been a growing acknowledgement of the involvement of the gut microbiome - the collection of microbes that reside in our gut - in regulating our mood and behaviour. This phenomenon is referred to as the microbiome-gut-brain axis.…
One of the central themes in modern ecology is the enduring debate on whether there is a relationship between the complexity of a biological community and its stability. In this paper, we focus on the role of detritus and spatial dispersion…
The gut microbiota features important genetic diversity, and the specific spatial features of the gut may shape evolution within this environment. We investigate the fixation probability of neutral bacterial mutants within a minimal model…
We utilize dynamical modes as features derived from Continuous Glucose Monitoring (CGM) data to detect meal events. By leveraging the inherent properties of underlying dynamics, these modes capture key aspects of glucose variability,…
Food webs are networks describing who is eating whom in an ecological community. By now it is clear that many aspects of food-web structure are reproducible across diverse habitats, yet little is known about the driving force behind this…
Ecological modelling of increasingly more complex microbial populations is necessary to reflect the highly functional and diverse behaviour inherent to many systems found in reality. Anaerobic digestion is one such process that has…
We develop a stochastic, individual-based model for food web simulation which in the large-population limit reduces to the well-studied Webworld model, which has been used to successfully construct model food webs with several realistic…
Consumption of food in excess of the required optimal nutritional requirements has already resulted in a global crisis and this is from the perspective of human health, such as obesity, as well as food waste and sustainability. In order to…