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While observational data are routinely used to estimate causal effects of biomedical treatments, doing so requires special methods to adjust for observed confounding. These methods invariably rely on untestable statistical and causal…

Development and optimization of biopharmaceutical production processes with cell cultures is cost- and time-consuming and often performed rather empirically. Efficient optimization of multiple-objectives like process time, viable cell…

As the decisions made or influenced by machine learning models increasingly impact our lives, it is crucial to detect, understand, and mitigate unfairness. But even simply determining what "unfairness" should mean in a given context is…

Growing individualization of products up to lot-size-1 and high volatility of product mixes lead to new challenges in the manufacturing domain, including the need for frequent reconfiguration of the system and reacting to changing orders.…

Feature attributions based on the Shapley value are popular for explaining machine learning models; however, their estimation is complex from both a theoretical and computational standpoint. We disentangle this complexity into two factors:…

The Shapley value, originating from cooperative game theory, has been employed to define responsibility measures that quantify the contributions of database facts to obtaining a given query answer. For non-numeric queries, this is done by…

Few Bayesian methods for analyzing high-dimensional sparse survival data provide scalable variable selection, effect estimation and uncertainty quantification. Such methods often either sacrifice uncertainty quantification by computing…

A growing family of approaches to causal inference rely on Bayesian formulations of assumptions that go beyond causal graph structure. For example, Bayesian approaches have been developed for analyzing instrumental variable designs,…

Despite their enormous predictive power, machine learning models are often unsuitable for applications in regulated industries such as finance, due to their limited capacity to provide explanations. While model-agnostic frameworks such as…

Shapley values have become increasingly popular in the machine learning literature thanks to their attractive axiomatisation, flexibility, and uniqueness in satisfying certain notions of `fairness'. The flexibility arises from the myriad…

Bayesian decision analysis is a useful method for risk management decisions, but is limited in its ability to consider severe uncertainty in knowledge, and value ambiguity in management objectives. We study the use of robust Bayesian…

Biotic stress consists of damage to plants through other living organisms. Efficient control of biotic agents such as pests and pathogens (viruses, fungi, bacteria, etc.) is closely related to the concept of agricultural sustainability.…

Precision medicine stands as a transformative approach in healthcare, offering tailored treatments that can enhance patient outcomes and reduce healthcare costs. As understanding of complex disease improves, clinical trials are being…

In clinical prediction settings the importance of a high-dimensional feature like genomics is often assessed by evaluating the change in predictive performance when adding it to a set of traditional clinical variables. This approach is…

Quantifying the inconsistency of a database is motivated by various goals including reliability estimation for new datasets and progress indication in data cleaning. Another goal is to attribute to individual tuples a level of…

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

Besides accuracy, recent studies on machine learning models have been addressing the question on how the obtained results can be interpreted. Indeed, while complex machine learning models are able to provide very good results in terms of…

Root Cause Analysis (RCA) in the manufacturing of electric vehicles is the process of identifying fault causes. Traditionally, the RCA is conducted manually, relying on process expert knowledge. Meanwhile, sensor networks collect…

Emotion recognition from social media is critical for understanding public sentiment, but accessing training data has become prohibitively expensive due to escalating API costs and platform restrictions. We introduce an…

Financial forecasting plays an important role in making informed decisions for financial stakeholders, specifically in the stock exchange market. In a traditional setting, investors commonly rely on the equity research department for…