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Dynamic Treatment Regimes (DTRs) provide a systematic framework for optimizing sequential decision-making in chronic disease management, where therapies must adapt to patients' evolving clinical profiles. Inverse probability weighting (IPW)…

Methodology · Statistics 2026-03-26 Chloe Si , David A. Stephens , Erica E. M. Moodie

An individualized treatment rule (ITR) tailors treatments to a patient's specific characteristics. However, randomized controlled trials (RCTs) are often underpowered to detect the treatment effect heterogeneity needed for reliable ITR…

Methodology · Statistics 2026-04-14 Yuan Bian , Donglin Zeng , Hyun-Joon Yang , Leanne M. Williams , Yuanjia Wang

Precision medicine is an emerging scientific topic for disease treatment and prevention that takes into account individual patient characteristics. It is an important direction for clinical research, and many statistical methods have been…

Methodology · Statistics 2017-02-17 Jingxiang Chen , Haoda Fu , Xuanyao He , Michael R. Kosorok , Yufeng Liu

Inverse reinforcement learning (IRL) and dynamic discrete choice (DDC) models explain sequential decision-making by recovering reward functions that rationalize observed behavior. Flexible IRL methods typically rely on machine learning but…

Machine Learning · Computer Science 2026-01-01 Lars van der Laan , Aurelien Bibaut , Nathan Kallus

This paper is about optimal estimation of the additive components of a nonparametric, additive isotone regression model. It is shown that asymptotically up to first order, each additive component can be estimated as well as it could be by a…

Statistics Theory · Mathematics 2007-09-12 Enno Mammen , Kyusang Yu

Distribution regression, where the goal is to predict a scalar response from a distribution-valued predictor, arises naturally in settings where observations are grouped and outcomes depend on group-level characteristics rather than on…

Methodology · Statistics 2026-03-09 Antonio R. Linero , Soumyabrata Bose , Jared Murray

Sliced Inverse Regression (SIR) is an effective method for dimension reduction in high-dimensional regression problems. The original method, however, requires the inversion of the predictors covariance matrix. In case of collinearity…

Statistics Theory · Mathematics 2011-04-01 C. Bernard-Michel , L. Gardes , S. Girard

Compositional data arise when count observations are normalised into proportions adding up to unity. To allow use of standard statistical methods, compositional proportions can be mapped from the simplex into the Euclidean space through the…

Methodology · Statistics 2025-07-04 Noora Kartiosuo , Joni Virta , Jaakko Nevalainen , Olli Raitakari , Kari Auranen

Integrated passive radar (IPR) can be regarded as next generation passive radar technology, which aims to integrate communication and radar systems. Unlike conventional passive radar, which does not prioritize communication-centric radar…

Signal Processing · Electrical Eng. & Systems 2024-02-27 Amir Zaimbashi , Maria Sabrina Greco , Fulvio Gini

Many real-world optimization problems involve uncertain parameters with probability distributions that can be estimated using contextual feature information. In contrast to the standard approach of first estimating the distribution of…

Machine Learning · Statistics 2023-08-03 Meng Qi , Paul Grigas , Zuo-Jun Max Shen

We propose a new method for parameter learning in Bayesian networks with qualitative influences. This method extends our previous work from networks of binary variables to networks of discrete variables with ordered values. The specified…

Artificial Intelligence · Computer Science 2012-06-26 Ad Feelders

Structured additive distributional regression models offer a versatile framework for estimating complete conditional distributions by relating all parameters of a parametric distribution to covariates. Although these models efficiently…

Methodology · Statistics 2023-11-14 Jana Kleinemeier , Nadja Klein

In this paper, we introduce a reduced order model-based reinforcement learning (MBRL) approach, utilizing the Iterative Linear Quadratic Regulator (ILQR) algorithm for the optimal control of nonlinear partial differential equations (PDEs).…

Systems and Control · Electrical Eng. & Systems 2025-01-14 Aayushman Sharma , Suman Chakravorty

Distributionally robust optimization (DRO) studies decision problems under uncertainty where the probability distribution governing the uncertain problem parameters is itself uncertain. A key component of any DRO model is its ambiguity set,…

Optimization and Control · Mathematics 2025-05-28 Daniel Kuhn , Soroosh Shafiee , Wolfram Wiesemann

Elliptically-contoured distributions (ECD) play a significant role, in computer vision, image processing, radar, and biomedical signal processing. Maximum likelihood. estimation (MLE) of ECD leads to a system of non-linear equations,…

Signal Processing · Electrical Eng. & Systems 2020-11-06 Jialun Zhou , Salem Said , Yannick Berthoumieu

Symbolic Data Analysis works with variables for which each unit or class of units takes a finite set of values/categories, an interval or a distribution (an histogram, for instance). When to each observation corresponds an empirical…

Methodology · Statistics 2013-05-01 Sónia Dias , Paula Brito

Regression methods for interval-valued data have been increasingly studied in recent years. As most of the existing works focus on linear models, it is important to note that many problems in practice are nonlinear in nature and therefore…

Methodology · Statistics 2022-01-11 Chih-Ching Yeh , Yan Sun , Adele Cutler

We propose a novel nonparametric regression framework subject to the positive definiteness constraint. It offers a highly modular approach for estimating covariance functions of stationary processes. Our method can impose positive…

Methodology · Statistics 2023-04-27 Myeongjong Kang

Dynamic treatment regimes (DTRs) provide a principled framework for optimizing sequential decision-making in domains where decisions must adapt over time in response to individual trajectories, such as healthcare, education, and digital…

Machine Learning · Statistics 2026-01-30 Ruijia Zhang , Xiangyu Zhang , Zhengling Qi , Yue Wu , Yanxun Xu

Informed down-sampling (IDS) is known to improve performance in symbolic regression when combined with various selection strategies, especially tournament selection. However, recent work found that IDS's gains are not consistent across all…

Neural and Evolutionary Computing · Computer Science 2026-01-28 Alina Geiger , Martin Briesch , Dominik Sobania , Franz Rothlauf