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In the majority of molecular optimization tasks, predictive machine learning (ML) models are limited due to the unavailability and cost of generating big experimental datasets on the specific task. To circumvent this limitation, ML models…

The implementation of deep learning based computer aided diagnosis systems for the classification of mammogram images can help in improving the accuracy, reliability, and cost of diagnosing patients. However, training a deep learning model…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Saul Calderon-Ramirez , Diego Murillo-Hernandez , Kevin Rojas-Salazar , David Elizondo , Shengxiang Yang , Miguel Molina-Cabello

In order to obtain morphological information of unlabeled galaxies, we present an unsupervised machine-learning (UML) method for morphological classification of galaxies, which can be summarized as two aspects: (1) the methodology of…

Astrophysics of Galaxies · Physics 2022-02-02 C. C. Zhou , Y. Z. Gu , G. W. Fang , Z. S. Lin

Machine learning holds tremendous promise for transforming the fundamental practice of scientific discovery by virtue of its data-driven nature. With the ever-increasing stream of research data collection, it would be appealing to…

Machine Learning · Computer Science 2024-03-06 Jianan Fan , Dongnan Liu , Hang Chang , Heng Huang , Mei Chen , Weidong Cai

Background. Radiomic features, derived from a region of interest (ROI) in medical images, are valuable as prognostic factors. Selecting an appropriate ROI is critical, and many recent studies have focused on leveraging multiple ROIs by…

We present BayesPIM, a Bayesian prevalence-incidence mixture model for estimating time- and covariate-dependent disease incidence from screening and surveillance data. The method is particularly suited to settings where some individuals may…

Methodology · Statistics 2026-01-12 Thomas Klausch , Birgit I. Lissenberg-Witte , Veerle M. Coupé

Medical image data are usually imbalanced across different classes. One-class classification has attracted increasing attention to address the data imbalance problem by distinguishing the samples of the minority class from the majority…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Shandong Wu

Semi-supervised learning (SSL) has made notable advancements in medical image segmentation (MIS), particularly in scenarios with limited labeled data and significantly enhancing data utilization efficiency. Previous methods primarily focus…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Mengzhu Wang , Jiao Li , Houcheng Su , Nan Yin , Liang Yang , Shen Li

Clustering mixed-type data remains a major challenge in biomedical research to uncover clinically meaningful subgroups within heterogeneous patient populations. Most existing clustering methods impose restrictive assumptions like local…

Applications · Statistics 2026-04-23 Yueting Wang , Shu Wang , Jonathan G. Yabes , Chung-Chou H. Chang

In the framework of Bayesian model-based clustering based on a finite mixture of Gaussian distributions, we present a joint approach to estimate the number of mixture components and identify cluster-relevant variables simultaneously as well…

Methodology · Statistics 2016-06-23 Gertraud Malsiner-Walli , Sylvia Frühwirth-Schnatter , Bettina Grün

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Recent emergence of high-throughput drug screening assays sparkled an intensive development of machine learning methods, including models for prediction of sensitivity of cancer cell lines to anti-cancer drugs, as well as methods for…

Machine Learning · Computer Science 2022-06-09 Krzysztof Koras , Marcin Możejko , Paulina Szymczak , Eike Staub , Ewa Szczurek

In many applications, multivariate samples may harbor previously unrecognized heterogeneity at the level of conditional independence or network structure. For example, in cancer biology, disease subtypes may differ with respect to…

Machine Learning · Statistics 2013-01-11 Steven M. Hill , Sach Mukherjee

Image clustering is one of the most important computer vision applications, which has been extensively studied in literature. However, current clustering methods mostly suffer from lack of efficiency and scalability when dealing with…

Machine Learning · Computer Science 2017-08-10 Kamran Ghasedi Dizaji , Amirhossein Herandi , Cheng Deng , Weidong Cai , Heng Huang

Deep clustering as an important branch of unsupervised representation learning focuses on embedding semantically similar samples into the identical feature space. This core demand inspires the exploration of contrastive learning and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Haifeng Xia , Hai Huang , Zhengming Ding

Brain pathologies can vary greatly in size and shape, ranging from few pixels (i.e. MS lesions) to large, space-occupying tumors. Recently proposed Autoencoder-based methods for unsupervised anomaly segmentation in brain MRI have shown…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Mammography and ultrasound are extensively used by radiologists as complementary modalities to achieve better performance in breast cancer diagnosis. However, existing computer-aided diagnosis (CAD) systems for the breast are generally…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Gavriel Habib , Nahum Kiryati , Miri Sklair-Levy , Anat Shalmon , Osnat Halshtok Neiman , Renata Faermann Weidenfeld , Yael Yagil , Eli Konen , Arnaldo Mayer

Local discriminative representation is needed in many medical image analysis tasks such as identifying sub-types of lesion or segmenting detailed components of anatomical structures. However, the commonly applied supervised representation…

Computer Vision and Pattern Recognition · Computer Science 2021-03-25 Huai Chen , Jieyu Li , Renzhen Wang , Yijie Huang , Fanrui Meng , Deyu Meng , Qing Peng , Lisheng Wang

Constructing a chemically diverse dataset while avoiding sampling bias is critical to training efficient and generalizable force fields. However, in computational chemistry and materials science, many common dataset generation techniques…

Machine Learning · Computer Science 2025-09-17 Hong Sun , Joshua A. Vita , Amit Samanta , Vincenzo Lordi

Recent developments in high throughput profiling of individual neurons have spurred data driven exploration of the idea that there exist natural groupings of neurons referred to as cell types. The promise of this idea is that the immense…

Neurons and Cognition · Quantitative Biology 2019-11-14 Rohan Gala , Nathan Gouwens , Zizhen Yao , Agata Budzillo , Osnat Penn , Bosiljka Tasic , Gabe Murphy , Hongkui Zeng , Uygar Sümbül
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