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Threshold-linear networks (TLNs) are models of neural networks that consist of simple, perceptron-like neurons and exhibit nonlinear dynamics that are determined by the network's connectivity. The fixed points of a TLN, including both…

Neurons and Cognition · Quantitative Biology 2018-08-06 Carina Curto , Jesse Geneson , Katherine Morrison

Combinatorial threshold-linear networks (CTLNs) are a special class of inhibition-dominated TLNs defined from directed graphs. Like more general TLNs, they display a wide variety of nonlinear dynamics including multistability, limit cycles,…

Neurons and Cognition · Quantitative Biology 2022-08-16 Caitlyn Parmelee , Samantha Moore , Katherine Morrison , Carina Curto

Nonlinear network dynamics are notoriously difficult to understand. Here we study a class of recurrent neural networks called combinatorial threshold-linear networks (CTLNs) whose dynamics are determined by the structure of a directed…

Neurons and Cognition · Quantitative Biology 2021-09-16 Daniela Egas Santander , Stefania Ebli , Alice Patania , Nicole Sanderson , Felicia Burtscher , Katherine Morrison , Carina Curto

Threshold-linear networks are a common class of firing rate models that describe recurrent interactions among neurons. Unlike their linear counterparts, these networks generically possess multiple stable fixed points (steady states), making…

Neurons and Cognition · Quantitative Biology 2016-12-28 Carina Curto , Katherine Morrison

Neural network models in neuroscience allow one to study how the connections between neurons shape the activity of neural circuits in the brain. In this chapter, we study Combinatorial Threshold-Linear Networks (CTLNs) in order to…

Neurons and Cognition · Quantitative Biology 2018-04-05 Katherine Morrison , Carina Curto

The architecture of a neural network constrains the potential dynamics that can emerge. Some architectures may only allow for a single dynamic regime, while others display a great deal of flexibility with qualitatively different dynamics…

Combinatorics · Mathematics 2020-08-04 Carina Curto , Christopher Langdon , Katherine Morrison

To any inhibition-dominated threshold-linear network (TLN) we can associate a directed graph that captures the pattern of strong and weak inhibition between neurons. Robust motifs are graphs for which the structure of fixed points in the…

Neurons and Cognition · Quantitative Biology 2019-12-18 Carina Curto , Christopher Langdon , Katherine Morrison

Graphical domination was first introduced in [1] in the context of combinatorial threshold-linear networks (CTLNs). There it was shown that when a domination relationship exists between a pair of vertices in a graph, certain fixed points in…

Neurons and Cognition · Quantitative Biology 2025-10-07 Carina Curto

In threshold-linear networks (TLNs), a fixed point is called minimal if no proper subset of its support is also a fixed point. Curto et al (Advances in Applied Mathematics, 2024) conjectured that every stable fixed point of any TLN must be…

Neurons and Cognition · Quantitative Biology 2025-11-11 Jesse Geneson

Sequences of neural activity arise in many brain areas, including cortex, hippocampus, and central pattern generator circuits that underlie rhythmic behaviors like locomotion. While network architectures supporting sequence generation vary…

Neurons and Cognition · Quantitative Biology 2022-08-16 Caitlyn Parmelee , Juliana Londono Alvarez , Carina Curto , Katherine Morrison

Networks of interconnected neurons display diverse patterns of collective activity. Relating this collective activity to the network's connectivity structure is a key goal of computational neuroscience. We approach this question for…

Neurons and Cognition · Quantitative Biology 2025-06-09 Caitlin Lienkaemper , Gabriel Koch Ocker

Graph Neural Networks (GNN) rely on graph convolutions to learn features from network data. GNNs are stable to different types of perturbations of the underlying graph, a property that they inherit from graph filters. In this paper we…

Machine Learning · Computer Science 2022-02-11 Juan Cervino , Luana Ruiz , Alejandro Ribeiro

Threshold-linear networks consist of simple units interacting in the presence of a threshold nonlinearity. Competitive threshold-linear networks have long been known to exhibit multistability, where the activity of the network settles into…

Neurons and Cognition · Quantitative Biology 2023-10-17 Katherine Morrison , Anda Degeratu , Vladimir Itskov , Carina Curto

Given a graph $G$, viewed as a loop-less symmetric digraph, we study the maximum number of fixed points in a conjunctive boolean network with $G$ as interaction graph. We prove that if $G$ has no induced $C_4$, then this quantity equals…

Combinatorics · Mathematics 2017-11-08 Julio Aracena , Adrien Richard , Lilian Salinas

Neural networks storing multiple discrete attractors are canonical models of biological memory. Previously, the dynamical stability of such networks could only be guaranteed under highly restrictive conditions. Here, we derive a theory of…

Disordered Systems and Neural Networks · Physics 2026-01-23 Uri Cohen , Máté Lengyel

Continuous time recurrent neural networks (CTRNN) are systems of coupled ordinary differential equations that are simple enough to be insightful for describing learning and computation, from both biological and machine learning viewpoints.…

Dynamical Systems · Mathematics 2021-06-18 Peter Ashwin , Claire M Postlethwaite

Recurrent neural networks are widely used in speech and language processing. Due to dependency on the past, standard algorithms for training these models, such as back-propagation through time (BPTT), cannot be efficiently parallelised.…

Audio and Speech Processing · Electrical Eng. & Systems 2021-06-07 Zhengxiong Wang , Anton Ragni

Graph convolutional neural networks (GCNNs) are nonlinear processing tools to learn representations from network data. A key property of GCNNs is their stability to graph perturbations. Current analysis considers deterministic perturbations…

Machine Learning · Computer Science 2021-06-22 Zhan Gao , Elvin Isufi , Alejandro Ribeiro

Convolutional Neural Networks (CNNs) have been applied to data with underlying non-Euclidean structures and have achieved impressive successes. This brings the stability analysis of CNNs on non-Euclidean domains into notice because CNNs…

Signal Processing · Electrical Eng. & Systems 2021-03-05 Zhiyang Wang , Luana Ruiz , Alejandro Ribeiro

Fixed points are fundamental states in any dynamical system. In the case of gene regulatory networks (GRNs) they correspond to stable genes profiles associated to the various cell types. We use Kauffman's approach to model GRNs with random…

Cell Behavior · Quantitative Biology 2012-03-08 Pablo Moisset de Espanés , Axel Osses , Iván Rapaport
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