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We propose a random-effects approach to missing values for generalized linear mixed model (GLMM) analysis. The method converts a GLMM with missing covariates to another GLMM without missing covariates. The standard GLMM analysis tools for…

Methodology · Statistics 2026-01-01 Thuan Nguyen , Jiangshan Zhang , Jiming Jiang

Missingness in categorical data is a common problem in various real applications. Traditional approaches either utilize only the complete observations or impute the missing data by some ad hoc methods rather than the true conditional…

Methodology · Statistics 2019-07-12 Chaojie Wang , Linghao Shen , Han Li , Xiaodan Fan

Missing data problems arise in many applied research studies. They may jeopardize statistical inference of the model of interest, if the missing mechanism is nonignorable, that is, the missing mechanism depends on the missing values…

Statistics Theory · Mathematics 2015-09-15 Wang Miao , Peng Ding , Zhi Geng

Missing data is pervasive in econometric applications, and rarely is it plausible that the data are missing (completely) at random. This paper proposes a methodology for studying the robustness of results drawn from incomplete datasets.…

Econometrics · Economics 2025-12-29 Daniel Ober-Reynolds

This paper proposes a simple and efficient estimation procedure for the model with non-ignorable missing data studied by Morikawa and Kim (2016). Their semiparametrically efficient estimator requires explicit nonparametric estimation and so…

Methodology · Statistics 2018-01-15 Chunrong Ai , Oliver Linton , Zheng Zhang

Maximum likelihood estimation is effective for identifying dynamical systems, but applying it to large networks becomes computationally prohibitive. This paper introduces a maximum likelihood estimation method that enables identification of…

Systems and Control · Electrical Eng. & Systems 2025-11-06 João Victor Galvão da Mata , Anders Hansson , Martin S. Andersen

Causally interpretable meta-analysis combines information from a collection of randomized controlled trials to estimate treatment effects in a target population in which experimentation may not be possible but covariate information can be…

Methodology · Statistics 2022-05-03 Jon A. Steingrimsson , David H. Barker , Ruofan Bie , Issa J. Dahabreh

Assuming a steady-state condition within a cell, metabolic fluxes satisfy an under-determined linear system of stoichiometric equations. Characterizing the space of fluxes that satisfy such equations along with given bounds (and possibly…

Biological Physics · Physics 2017-04-10 Alfredo Braunstein , Anna Paola Muntoni , Andrea Pagnani

Data from discovery proteomic and phosphoproteomic experiments typically include missing values that correspond to proteins that have not been identified in the analyzed sample. Replacing the missing values with random numbers, a process…

Quantitative Methods · Quantitative Biology 2019-10-01 Matus Medo , Daniel M. Aebersold , Michaela Medova

Gaussian Mixture models (GMMs) are a powerful tool for clustering, classification and density estimation when clustering structures are embedded in the data. The presence of missing values can largely impact the GMMs estimation process,…

Machine Learning · Statistics 2020-06-05 Alessio Serafini , Thomas Brendan Murphy , Luca Scrucca

With nonignorable missing data, likelihood-based inference should be based on the joint distribution of the study variables and their missingness indicators. These joint models cannot be estimated from the data alone, thus requiring the…

Statistics Theory · Mathematics 2017-01-06 Mauricio Sadinle , Jerome P. Reiter

Advancements in data collection techniques and the heterogeneity of data resources can yield high percentages of missing observations on variables, such as block-wise missing data. Under missing-data scenarios, traditional methods such as…

Methodology · Statistics 2022-05-17 Wei Lan , Xuerong Chen , Tao Zou , Chih-Ling Tsai

Motivated by the challenges in analyzing gut microbiome and metagenomic data, this work aims to tackle the issue of measurement errors in high-dimensional regression models that involve compositional covariates. This paper marks a…

Methodology · Statistics 2024-09-13 Huali Zhao , Tianying Wang

Latent variable models provide a powerful framework for incorporating and inferring unobserved factors in observational data. In causal inference, they help account for hidden factors influencing treatment or outcome, thereby addressing…

Machine Learning · Computer Science 2025-08-29 Tetsuro Morimura , Tatsushi Oka , Yugo Suzuki , Daisuke Moriwaki

Missing data theory deals with the statistical methods in the occurrence of missing data. Missing data occurs when some values are not stored or observed for variables of interest. However, most of the statistical theory assumes that data…

A frequent problem in statistical science is how to properly handle missing data in matched paired observations. There is a large body of literature coping with the univariate case. Yet, the ongoing technological progress in measuring…

Methodology · Statistics 2022-06-06 Marcos Matabuena , Paulo Félix , Marc Ditzhaus , Juan Vidal , Francisco Gude

The existence and consistency of a maximum likelihood estimator for the joint probability distribution of random parameters in discrete-time abstract parabolic systems are established by taking a nonparametric approach in the context of a…

Methodology · Statistics 2023-04-26 Lernik Asserian , Susan E. Luczak , I. G. Rosen

The problem of monotone missing data has been broadly studied during the last two decades and has many applications in different fields such as bioinformatics or statistics. Commonly used imputation techniques require multiple iterations…

Machine Learning · Computer Science 2020-09-25 Thu Nguyen , Duy H. M. Nguyen , Huy Nguyen , Binh T. Nguyen , Bruce A. Wade

In our paper, we focus on robust variable selection for missing data and measurement error. Missing data and measurement errors can lead to confusing data distribution. We propose an exponential loss function with a tuning parameter to…

Methodology · Statistics 2025-07-01 Zhenhao Zhang , Yunquan Song

The global prevalence of diabetes, particularly type 2 diabetes mellitus (T2DM), is rapidly increasing, posing significant health and economic challenges. T2DM not only disrupts blood glucose regulation but also damages vital organs such as…

Machine Learning · Computer Science 2025-06-09 Praveen Kumar , Vincent T. Metzger , Scott A. Malec