Related papers: An element-wise approach for simulating transcrani…
Transcranial MRI-guided focused ultrasound (TcMRgFUS) thermal ablation is a noninvasive functional neurosurgery technique. Previous reports have shown that bone marrow damage in the skull can occur at high acoustic energies. While this…
Transcranial MRI-guided focused ultrasound (TcMRgFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively under MRI guidance. It is clinically approved to thermally ablate regions of the…
Intracorporeal needle-based therapeutic ultrasound (NBTU) is a minimally invasive option for intervening in malignant brain tumors, commonly used in thermal ablation procedures. This technique is suitable for both primary and metastatic…
Neurosurgery targets in the thalamus can be challenging to identify during transcranial MRI-guided focused ultrasound (MRgFUS) thermal ablation due to poor image quality. They also neighbor structures that can result in side effects if…
High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict…
Accurate and efficient prediction of soft tissue temperatures is essential to computer-assisted treatment systems for thermal ablation. It can be used to predict tissue temperatures and ablation volumes for personalised treatment planning…
Transcranial focused ultrasound (tFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively and often under MRI guidance. CT imaging is used to estimate the acoustic properties that vary…
Transcranial ultrasound therapy uses focused acoustic energy to induce therapeutic bioeffects in the brain. Ultrasound must be transmitted through the skull, which is highly attenuating and heterogeneous, causing beam distortion, reducing…
Transcranial ultrasound (TUS) has emerged as a promising tool in clinical and research settings due to its potential to modulate neuronal activity, open the blood-brain barrier, facilitate targeted drug delivery via nanoparticles, and…
Objective: The aim of this study was to evaluate the efficacy of alendronate therapy in improving bone density distribution in skull bones and corresponding ultrasound permeability in patients who had previously experienced unsuccessful…
Transcranial focused ultrasound (tFUS) is an emerging form of non-surgical human neuromodulation that confers advantages over existing electro and electromagnetic technologies by providing a superior spatial resolution on the millimeter…
Intracorporeal needle-based therapeutic ultrasound (NBTU) offers a minimally invasive approach for the thermal ablation of malignant brain tumors, including both primary and metastatic cancers. NBTU utilizes a high-frequency alternating…
Transcranial focused ultrasound (tFUS) is an emerging modality for non-invasive brain stimulation and therapeutic intervention, offering millimeter-scale spatial precision and the ability to target deep brain structures. However, the…
Over the past decades, thermal ablation procedures such as high intensity focused ultrasound (HIFU) have been developed vaporize cancerous tissues in a focal area. Thermal ablation has the potential to non-invasively eliminate tumors and…
Objective. While ultrasound is largely established for use in diagnostic imaging and heating therapies, its application for neuromodulation is relatively new and not well understood. The objective of the present study was to investigate…
The femtosecond laser pulse heating of silver film is investigated by performing quantum mechanics (QM), molecular dynamics (MD) and two temperature model (TTM) integrated multiscale simulation. The laser excitation dependent electron…
Transcranial focused ultrasound (tFUS) offers noninvasive access to deep brain circuits but remains limited by skull-induced phase aberration, acoustic impedance mismatch, and poor volumetric control of intracranial pressure fields.…
Transcranial focused ultrasound (FUS) is a non-invasive technique for therapy and study of brain neural activation. Here we report on the design and characterization of a new MR-guided FUS transducer for neuromodulation in non-human…
Objective: In this review, we aim to provide an analysis of current cardiac ablation techniques, such as radiofrequency ablation (RF), cryoablation, and pulsed-field ablation (PFA), with a focus on the role of computational modeling in…
Hyperthermia therapy (HT) is used to treat diseases through heating of high temperature usually in conjunction with some other medical therapeutics like chemotherapy and radiotherapy. In this study, we propose a promising thermostatic…