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This manuscript introduces a novel method to assess tissue oxygen concentration via the quantum entanglement (QE) of photons originating from positronium which is produced within the patient's body during positron emission tomography. We…

Medical Physics · Physics 2026-05-05 Pawel Moskal

Hyperion-IID is a positron emission tomography (PET) insert which allows simultaneous operation in a clinical magnetic resonance imaging (MRI) scanner. To read out the scintillation light of the employed LYSO crystal arrays with a pitch of…

We consider the problem of localization of Poisson source by the observations of inhomogeneous Poisson processes. We suppose that there are $k$ detectors on the plane and each detector provides the observations of Poisson processes whose…

Statistics Theory · Mathematics 2018-06-19 Oleg V. Chernoyarov , Yury A. Kutoyants

Current state-of-the-art results in computer vision depend in part on fine-tuning large pre-trained vision models. However, with the exponential growth of model sizes, the conventional full fine-tuning, which needs to store a individual…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Shibo Jie , Haoqing Wang , Zhi-Hong Deng

We report on an hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA…

Objective: To construct an analytical model instead of local effect modeling for the prediction of the biological effectiveness of nanoparticle radiosensitization. Approach: An extended local effects model is first proposed with a more…

This work is concerned with the identifiability of metabolic parameters from multi-region measurement data in quantitative PET imaging. It shows that, for the frequently used two-tissue compartment model and under reasonable assumptions, it…

Optimization and Control · Mathematics 2023-05-29 Martin Holler , Erion Morina , Georg Schramm

We propose PET scanners using low atomic number media that undergo a persistent local change of state along the paths of the Compton recoil electrons. Measurement of the individual scattering locations and angles, deposited energies, and…

Microdosimetry provides a superior characterization of the radiation field compared to conventional LET-based methodology, and for this reason it has become increasingly attractive for quality assurance in particle therapy. However, the…

Medical Physics · Physics 2025-04-08 E. Pierobon , M. Missiaggia , F. G. Cordoni , C. La Tessa

Bone marrow (BM) metabolic quantification with 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is of broad clinical significance for accurate assessment of BM at staging and follow-up, especially when immunotherapy is…

Accurately predicting conditional average treatment effects (CATEs) is crucial in personalized medicine and digital platform analytics. Since the treatments of interest often cannot be directly randomized, observational data is leveraged to…

Methodology · Statistics 2024-11-05 Miruna Oprescu , Nathan Kallus

Photoplethysmography (PPG) is a non-invasive technology that measures changes in blood volume in the microvascular bed of tissue. It is commonly used in medical devices such as pulse oximeters and wrist worn heart rate monitors to monitor…

Photoplethysmography (PPG) sensors allow for non-invasive and comfortable heart-rate (HR) monitoring, suitable for compact wrist-worn devices. Unfortunately, Motion Artifacts (MAs) severely impact the monitoring accuracy, causing high…

Purpose: In treatment planning of charged-particle radiotherapy, patient heterogeneity is conventionally modeled as variable-density water converted from CT images to best reproduce the stopping power, which may lead to inaccuracies in the…

Medical Physics · Physics 2013-01-08 Nobuyuki Kanematsu , Taku Inaniwa , Yusuke Koba

Low-energy electron microscopy (LEEM) taken as intensity-voltage (I-V) curves provides hyperspectral images of surfaces, which can be used to identify the surface type, but are difficult to analyze. Here, we demonstrate the use of an…

Materials Science · Physics 2023-03-30 Francesco Masia , Wolfgang Langbein , Simon Fischer , Jon-Olaf Krisponeit , Jens Falta

Objective- Heart rate monitoring using wrist type Photoplethysmographic (PPG) signals is getting popularity because of construction simplicity and low cost of wearable devices. The task becomes very difficult due to the presence of various…

This work is devoted to the problem of estimation of the localization of Poisson source. The observations are inhomogeneous Poisson processes registered by the $k\geq 3$ detectors on the plane. We study the behavior of the Bayes estimators…

Statistics Theory · Mathematics 2018-06-20 O. V. Chernoyarov , S. Dachian , Yu. A. Kutoyants

Phosphorescent metal complexes have been under intense investigations as emissive dopants for energy efficient organic light emitting diodes (OLEDs). Among them, cyclometalated Pt(II) complexes are widespread triplet emitters with…

Machine Learning · Computer Science 2023-01-16 Shuai Wang , ChiYung Yam , Shuguang Chen , Lihong Hu , Liping Li , Faan-Fung Hung , Jiaqi Fan , Chi-Ming Che , GuanHua Chen

Intensity-modulated proton therapy (IMPT) employs proton radiation rather than conventional X-rays to treat cancerous tumors. This approach offers significant advantages by minimizing the radiation exposure of surrounding healthy tissue,…

Accurate single photoelectron (SPE) characterization of photosensors is essential for controlling systematic uncertainties in low-light neutrino and dark matter detectors. We present a compact laboratory setup for the characterization of…

Instrumentation and Detectors · Physics 2026-03-24 Matthias Raphael Stock , Hans Th. J. Steiger , Ulrike Fahrendholz , Luca Schweizer , Lothar Oberauer