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This study investigates explainable machine learning algorithms for identifying depression from speech. Grounded in evidence from speech production that depression affects motor control and vowel generation, pre-trained vowel-based…

Machine Learning · Computer Science 2024-10-25 Kexin Feng , Theodora Chaspari

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

Depression is a widespread mental health disorder, yet its automatic detection remains challenging. Prior work has explored unimodal and multimodal approaches, with multimodal systems showing promise by leveraging complementary signals.…

Artificial Intelligence · Computer Science 2026-03-24 Annisaa Fitri Nurfidausi , Eleonora Mancini , Paolo Torroni

Machine learning (ML) techniques have gained popularity in the neuroimaging field due to their potential for classifying neuropsychiatric disorders. However, the diagnostic predictive power of the existing algorithms has been limited by…

Large-scale collaborative analysis of brain imaging data, in psychiatry and neu-rology, offers a new source of statistical power to discover features that boost ac-curacy in disease classification, differential diagnosis, and outcome…

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

Neurons and Cognition · Quantitative Biology 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan

Depression is a widespread mental health issue, affecting an estimated 3.8% of the global population. It is also one of the main contributors to disability worldwide. Recently it is becoming popular for individuals to use social media…

Computation and Language · Computer Science 2024-03-21 Ziyi Chen , Ren Yang , Sunyang Fu , Nansu Zong , Hongfang Liu , Ming Huang

Depression is a mental health disorder that has a profound impact on people's lives. Recent research suggests that signs of depression can be detected in the way individuals communicate, both through spoken words and written texts. In…

Computation and Language · Computer Science 2023-10-18 Fardin Ahsan Sakib , Ahnaf Atef Choudhury , Ozlem Uzuner

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Weichen Huang

Previous studies have demonstrated that emotional features from a single acoustic sentiment label can enhance depression diagnosis accuracy. Additionally, according to the Emotion Context-Insensitivity theory and our pilot study,…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-30 Rongfeng Su , Changqing Xu , Xinyi Wu , Feng Xu , Xie Chen , Lan Wangt , Nan Yan

The primary method for identifying mental disorders automatically has traditionally involved using binary classifiers. These classifiers are trained using behavioral data obtained from an interview setup. In this training process, data from…

Neurons and Cognition · Quantitative Biology 2023-08-11 Rohan Kumar Gupta , Rohit Sinha

We describe the development of a model to detect user-level clinical depression based on a user's temporal social media posts. Our model uses a Depression Symptoms Detection (DSD) classifier, which is trained on the largest existing samples…

Computation and Language · Computer Science 2023-03-31 Nawshad Farruque , Randy Goebel , Sudhakar Sivapalan , Osmar R. Zaïane

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Suicide is one of the leading causes of death among adolescents. Previous suicide risk prediction studies have primarily focused on either textual or acoustic information in isolation, the integration of multimodal signals, such as speech…

Sound · Computer Science 2025-09-03 Wenqiang Sun , Han Yin , Jisheng Bai , Jianfeng Chen

Depression is a common disease worldwide. It is difficult to diagnose and continues to be underdiagnosed. Because depressed patients constantly share their symptoms, major life events, and treatments on social media, researchers are turning…

Computation and Language · Computer Science 2025-10-27 Wenli Zhang , Jiaheng Xie , Zhu Zhang , Xiang Liu

Bipolar disorder (BD) is closely associated with an increased risk of suicide. However, while the prior work has revealed valuable insight into understanding the behavior of BD patients on social media, little attention has been paid to…

Computation and Language · Computer Science 2023-07-06 Daeun Lee , Sejung Son , Hyolim Jeon , Seungbae Kim , Jinyoung Han

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Depression is a significant mental health concern, particularly in professional environments where work-related stress, financial pressure, and lifestyle imbalances contribute to deteriorating well-being. Despite increasing awareness,…

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Prevalent empathy prediction techniques primarily concentrate on a singular modality, typically textual, thus neglecting multi-modal processing capabilities. They also overlook the utilization of certain privileged information, which may…

Artificial Intelligence · Computer Science 2025-12-03 Yufei Xiao , Shangfei Wang