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Most of the classical denoising methods restore clear results by selecting and averaging pixels in the noisy input. Instead of relying on hand-crafted selecting and averaging strategies, we propose to explicitly learn this process with deep…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Xiangyu Xu , Muchen Li , Wenxiu Sun

Medical image segmentation is vital for modern healthcare and is a key element of computer-aided diagnosis. While recent advancements in computer vision have explored unsupervised segmentation using pre-trained models, these methods have…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Mosong Ma , Tania Stathaki , Michalis Lazarou

Cell counting in microscopy images is vital in medicine and biology but extremely tedious and time-consuming to perform manually. While automated methods have advanced in recent years, state-of-the-art approaches tend to increasingly…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Zixuan Zheng , Yilei Shi , Chunlei Li , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Image denoising is a typical ill-posed problem due to complex degradation. Leading methods based on normalizing flows have tried to solve this problem with an invertible transformation instead of a deterministic mapping. However, the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Wenchao Du , Hu Chen , Yi Zhang , H. Yang

In this work, we present denoiSplit, a method to tackle a new analysis task, i.e. the challenge of joint semantic image splitting and unsupervised denoising. This dual approach has important applications in fluorescence microscopy, where…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Ashesh Ashesh , Florian Jug

The need for labour intensive pixel-wise annotation is a major limitation of many fully supervised learning methods for segmenting bioimages that can contain numerous object instances with thin separations. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Peter Schuetz , Carola-Bibiane Schönlieb

Image denoising can be described as the problem of mapping from a noisy image to a noise-free image. The best currently available denoising methods approximate this mapping with cleverly engineered algorithms. In this work we attempt to…

Computer Vision and Pattern Recognition · Computer Science 2012-11-12 Harold Christopher Burger , Christian J. Schuler , Stefan Harmeling

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

With the development of multimodality and large language models, the deep learning-based technique for medical image captioning holds the potential to offer valuable diagnostic recommendations. However, current generic text and image…

Computer Vision and Pattern Recognition · Computer Science 2024-01-02 Zhenyu Zhang , Benlu Wang , Weijie Liang , Yizhi Li , Xuechen Guo , Guanhong Wang , Shiyan Li , Gaoang Wang

We describe a novel method for training high-quality image denoising models based on unorganized collections of corrupted images. The training does not need access to clean reference images, or explicit pairs of corrupted images, and can…

Machine Learning · Computer Science 2019-10-29 Samuli Laine , Tero Karras , Jaakko Lehtinen , Timo Aila

Recent advancements in text-to-image generative models have demonstrated a remarkable ability to capture a deep semantic understanding of images. In this work, we leverage this semantic knowledge to transfer the visual appearance between…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yuval Alaluf , Daniel Garibi , Or Patashnik , Hadar Averbuch-Elor , Daniel Cohen-Or

Plant phenotyping refers to a quantitative description of the plants properties, however in image-based phenotyping analysis, our focus is primarily on the plants anatomical, ontogenetical and physiological properties.This technique…

Computer Vision and Pattern Recognition · Computer Science 2022-10-25 Petros N. Tamvakis , Chairi Kiourt , Alexandra D. Solomou , George Ioannakis , Nestoras C. Tsirliganis

When capturing and storing images, devices inevitably introduce noise. Reducing this noise is a critical task called image denoising. Deep learning has become the de facto method for image denoising, especially with the emergence of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Haoyu Chen , Jinjin Gu , Yihao Liu , Salma Abdel Magid , Chao Dong , Qiong Wang , Hanspeter Pfister , Lei Zhu

The spread of microbial infections is governed by the self-organization of bacteria on surfaces. Limitations of live imaging techniques make collective behaviors in clinically relevant systems challenging to quantify. Here, novel…

Biological Physics · Physics 2024-07-19 Vincent Hickl , Abid Khan , René M. Rossi , Bruno F. B. Silva , Katharina Maniura-Weber

Cell boundary information is crucial for analyzing cell behaviors from time-lapse microscopy videos. Existing supervised cell segmentation tools, such as ImageJ, require tuning various parameters and rely on restrictive assumptions about…

Applications · Statistics 2026-01-27 Laura Baracaldo , Blythe King , Haoran Yan , Yizi Lin , Nina Miolane , Mengyang Gu

Ultrasound imaging is challenging to interpret due to non-uniform intensities, low contrast, and inherent artifacts, necessitating extensive training for non-specialists. Advanced representation with clear tissue structure separation could…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Oleksandra Tmenova , Yordanka Velikova , Mahdi Saleh , Nassir Navab

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

The capability of image semantic segmentation may be deteriorated due to noisy input image, where image denoising prior to segmentation helps. Both image denoising and semantic segmentation have been developed significantly with the advance…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Shunxin Xu , Ke Sun , Dong Liu , Zhiwei Xiong , Zheng-Jun Zha

Microscopy image enhancement plays a pivotal role in understanding the details of biological cells and materials at microscopic scales. In recent years, there has been a significant rise in the advancement of microscopy image enhancement,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-29 Debasish Dutta , Neeharika Sonowal , Risheraj Barauh , Deepjyoti Chetia , Sanjib Kr Kalita