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Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…
Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…
Background/Aims: Standard Automated Perimetry (SAP) is the gold standard to monitor visual field (VF) loss in glaucoma management, but is prone to intra-subject variability. We developed and validated a deep learning (DL) regression model…
Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…
Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…
Non-destructive testing (NDT) is essential in ceramic manufacturing to ensure the quality of components without compromising their integrity. In this context, Optical Coherence Tomography (OCT) enables high-resolution internal imaging,…
Segmentation of retinal layers from Optical Coherence Tomography (OCT) volumes is a fundamental problem for any computer aided diagnostic algorithm development. This requires preprocessing steps such as denoising, region of interest…
Purpose: To develop a deep learning approach to de-noise optical coherence tomography (OCT) B-scans of the optic nerve head (ONH). Methods: Volume scans consisting of 97 horizontal B-scans were acquired through the center of the ONH using a…
Purpose: Optical Coherence Tomography Angiography (OCT-A) permits visualization of the changes to the retinal circulation due to diabetic retinopathy (DR), a microvascular complication of diabetes. We demonstrate accurate segmentation of…
Diabetic retinopathy screening traditionally relies on fundus photography, requiring specialized equipment and expertise often unavailable in primary care and resource limited settings. We developed and validated a deep learning (DL) system…
This paper proposes an automated method for the segmentation and extraction of the posterior segment of the human eye, including the vitreous, retina, choroid, and sclera compartments, using multi-vendor optical coherence tomography (OCT)…
Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…
Glaucoma is a progressive eye disease that leads to optic nerve damage, causing irreversible vision loss if left untreated. Optical coherence tomography (OCT) has become a crucial tool for glaucoma diagnosis, offering high-resolution 3D…
Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…
Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…
Multiple-surface segmentation in Optical Coherence Tomography (OCT) images is a challenge problem, further complicated by the frequent presence of weak image boundaries. Recently, many deep learning (DL) based methods have been developed…
Purpose: The optic nerve head (ONH) undergoes complex and deep 3D morphological changes during the development and progression of glaucoma. Optical coherence tomography (OCT) is the current gold standard to visualize and quantify these…
Accurate segmentation of macular edema, a hallmark pathological feature in vision-threatening conditions such as age-related macular degeneration and diabetic macular edema, is essential for clinical diagnosis and management. To overcome…
Glaucoma is a chronic eye disease characterized by optic neuropathy, leading to irreversible vision loss. It progresses gradually, often remaining undiagnosed until advanced stages. Early detection is crucial to monitor atrophy and develop…
Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…