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Choosing the most adequate kernel is crucial in many Machine Learning applications. Gaussian Process is a state-of-the-art technique for regression and classification that heavily relies on a kernel function. However, in the Gaussian…

Machine Learning · Computer Science 2019-10-15 Ibai Roman , Roberto Santana , Alexander Mendiburu , Jose A. Lozano

Not long ago primary census data became available to publicity. It opened qualitatively new perspectives not only for researchers in demography and sociology, but also for those people, who somehow face processes occurring in society. In…

Databases · Computer Science 2011-06-28 Oleg Chertov , Marharyta Aleksandrova

Background: The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples and hybridization important issues. We address…

Quantitative Methods · Quantitative Biology 2007-05-23 S. Bilke , T. Breslin , M. Sigvardsson

We propose a novel methodology for feature screening in clustering massive datasets, in which both the number of features and the number of observations can potentially be very large. Taking advantage of a fusion penalization based convex…

Methodology · Statistics 2017-10-05 Trambak Banerjee , Gourab Mukherjee , Peter Radchenko

Many real-life data are described by categorical attributes without a pre-classification. A common data mining method used to extract information from this type of data is clustering. This method group together the samples from the data…

Machine Learning · Computer Science 2014-07-30 Fabricio Olivetti de França

Unraveling the co-expression of genes across studies enhances the understanding of cellular processes. Inferring gene co-expression networks from transcriptome data presents many challenges, including spurious gene correlations, sample…

Machine Learning · Statistics 2024-10-01 Teodora Pandeva , Martijs Jonker , Leendert Hamoen , Joris Mooij , Patrick Forré

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

Medical Physics · Physics 2020-06-17 Changhee Lee , Mihaela van der Schaar

In the postgenome era many efforts have been dedicated to systematically elucidate the complex web of interacting genes and proteins. These efforts include experimental and computational methods. Microarray technology offers an opportunity…

Molecular Networks · Quantitative Biology 2009-08-04 L. Diambra

In this paper we present a novel iterative multiphase clustering technique for efficiently clustering high dimensional data points. For this purpose we implement clustering feature (CF) tree on a real data set and a Gaussian density…

Machine Learning · Computer Science 2014-11-13 Chandrima Sarkar , Atanu Roy

Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can…

Subcellular Processes · Quantitative Biology 2019-06-19 Jingyu Zhang , Hengyu Chen , Ruoyan Li , David A. Taft , Guang Yao , Fan Bai , Jianhua Xing

Big Data processing systems handle huge unstructured and structured data to store, process, and analyze through cluster analysis which helps in identifying unseen patterns to find the relationships between them. Clustering analysis over the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-11 Dipesh Gyawali

Constrained clustering has gained significant attention in the field of machine learning as it can leverage prior information on a growing amount of only partially labeled data. Following recent advances in deep generative models, we…

Machine Learning · Computer Science 2022-02-02 Laura Manduchi , Kieran Chin-Cheong , Holger Michel , Sven Wellmann , Julia E. Vogt

Data discretization, also known as binning, is a frequently used technique in computer science, statistics, and their applications to biological data analysis. We present a new method for the discretization of real-valued data into a finite…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Elena S. Dimitrova , John J. McGee , Reinhard C. Laubenbacher

The advent of the big data paradigm has transformed how industries manage and analyze information, ushering in an era of unprecedented data volume, velocity, and variety. Within this landscape, mixed-data clustering has become a critical…

Machine Learning · Computer Science 2025-12-04 Guillaume Guerard , Sonia Djebali

Clustering multivariate data is a pervasive task in many applied problems, particularly in social studies and life science. Model-based approaches to clustering rely on mixture models, where each mixture component corresponds to the kernel…

Methodology · Statistics 2026-01-22 Laura Ferrini , Federico Castelletti

In this work a new way to calculate the multivariate joint entropy is presented. This measure is the basis for a fast information-theoretic based evaluation of gene relevance in a Microarray Gene Expression data context. Its low complexity…

Quantitative Methods · Quantitative Biology 2013-02-08 Fernando González , Lluís A. Belanche

This paper introduces a novel technique to track structures in time evolving graphs. The method is based on a parameter free approach for three-dimensional co-clustering of the source vertices, the target vertices and the time. All these…

Machine Learning · Computer Science 2013-01-15 Romain Guigourès , Marc Boullé , Fabrice Rossi

Graph clustering is a fundamental and challenging task in the field of graph mining where the objective is to group the nodes into clusters taking into consideration the topology of the graph. It has several applications in diverse domains…

Machine Learning · Computer Science 2023-12-21 Aritra Bhowmick , Mert Kosan , Zexi Huang , Ambuj Singh , Sourav Medya

Statistical language models frequently suffer from a lack of training data. This problem can be alleviated by clustering, because it reduces the number of free parameters that need to be trained. However, clustered models have the following…

cmp-lg · Computer Science 2008-02-03 Joerg P. Ueberla

Functional data clustering is to identify heterogeneous morphological patterns in the continuous functions underlying the discrete measurements/observations. Application of functional data clustering has appeared in many publications across…

Methodology · Statistics 2022-10-04 Mimi Zhang , Andrew Parnell