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We propose a novel approach for predicting protein-peptide interactions using a bi-modal transformer architecture that learns an inter-facial joint distribution of residual contacts. The current data sets for crystallized protein-peptide…

Biomolecules · Quantitative Biology 2023-06-02 Justin Diamond , Markus Lill

In a recent paper Liang {\it et al.} [Nature {\bf 411}, 665 (2001)] showed experimentally, that metallic nanotubes, strongly coupled to external electrodes, may act as coherent molecular waveguides for electronic transport. The experimental…

Mesoscale and Nanoscale Physics · Physics 2009-11-07 S. Krompiewski , J. Martinek , J. Barnas

The surface impact and collisions of particle-laden nanodrops are studied using molecular dynamics computer simulations. The drops are composed of Lennard- Jones dimers and the particles are rigid spherical sections of a cubic lattice, with…

Soft Condensed Matter · Physics 2015-09-02 Joel Koplik

While experiments with one or two quantum emitters have become routine in various laboratories, scalable platforms for efficient optical coupling of many quantum systems remain elusive. To address this issue, we report on chip-based systems…

Biomolecules exhibit dynamic conformations critical to their functions, yet observing these processes at the single-molecule level under native conditions remains a formidable challenge. While surface immobilization has been widely used to…

Instrumentation and Detectors · Physics 2025-12-22 Funing Liu , Qitao Hu , Anton Sabantsev , Giovanni Di Muccio , Shuangshuang Zeng , Mauro Chinappi , Sebastian Deindl , Zhen Zhang

A macroscopically nominal flat surface is rough at the nanoscale level and consists of nanoasperities. Therefore, the frictional properties of the macroscale-level rough surface are determined by the mechanical behaviors of nanoasperity…

Mesoscale and Nanoscale Physics · Physics 2020-11-05 jianqiao Hu , Hengxu Song , Stefan Sandfeld , Xiaoming Liu , Yueguang Wei

Dielectrophoresis (DEP), the motion of polarizable particles in non-uniform electric fields, has become an important tool for the transport, separation, and characterization of microparticles in biomedical and nanoelectronics research. In…

Soft Condensed Matter · Physics 2009-11-11 E. Salonen , E. Terama , I. Vattulainen , M. Karttunen

With the recent important development of microfluidic systems, miniaturization of flow devices has become a real challenge. Microchannels, however, are characterized by a large surface to volume ratio, so that surface properties strongly…

Materials Science · Physics 2009-11-10 Cecile Cottin-Bizonne , Jean-Louis Barrat , Lyderic Bocquet , Elisabeth Charlaix

Controlling the temperature in architectures involving nanoparticles and substrates is a key issue for applications involving micro and nanoscale heat transfer. We study the thermal behavior of a single nanoparticle interacting with a flat…

Optics · Physics 2017-03-03 Houssem Kallel , Rémi Carminati , Karl Joulain

In living organisms, proteins and peptides are often under the influence of mechanical forces, especially in confined spaces such as membrane channels, ribosome exit tunnel, or proteasome gate. Due to the directional nature of proteins as…

Biological Physics · Physics 2025-02-25 Felipe C. Nepomuceno , Michal H. Kolář

Using X- ray photon correlation spectroscopy measurements on gold nanoparticles embedded in polymethylmethacrylate we provide evidence for existence of an intrinsic length scale for dynamic heterogeneity in polymer nanocomposites similar to…

Soft Condensed Matter · Physics 2008-10-01 S. Srivastava , A. K. Kandar , J. K. Basu , M. K. Mukhopadhyay , L. B. Lurio , S. Narayanan , S. K. Sinha

Nonlocal (spatial-dispersion) effects in multilayered metamaterials composed of periodic stacks of alternating, deeply subwavelength dielectric layers are known to be negligibly weak. Counterintuitively, under certain critical conditions,…

Optics · Physics 2018-10-03 Giuseppe Castaldi , Andrea Alù , Vincenzo Galdi

In this work, we provide an overview of how well-established concepts in the fields of quantum chemistry and material sciences have to be adapted when the quantum nature of light becomes important in correlated matter-photon problems.…

Quantum Physics · Physics 2017-04-12 Johannes Flick , Michael Ruggenthaler , Heiko Appel , Angel Rubio

Phase-modulated non-linear spectroscopy with higher harmonic demodulation has recently been suggested to provide information on many-body excitations. In the present work we theoretically investigate the application of this method to infer…

Quantum Physics · Physics 2017-05-29 Zeng-Zhao Li , Lukas Bruder , Frank Stienkemeier , Alexander Eisfeld

Live cell imaging using metallic nanoparticles as tags is an emerging technique to visualize long and highly dynamic processes due to the lack of photobleaching and high photon rate. However, the lack of excited states as compared to…

Mesoscale and Nanoscale Physics · Physics 2011-01-12 H. E. Grecco , O. E. Martínez

In metal nanoparticles (NPs) supracrystals, the metallic core provides some key properties, e.g. magnetization, plasmonic response or conductivity, with the ligand molecules giving rise to others like solubility, assembly or interaction…

A unified model is constructed to study the recently observed DNA entropic elasticity, cooperative extensibility, and supercoiling property. With the introduction of a new structural parameter (the folding angle $\phi$), bending…

Soft Condensed Matter · Physics 2007-05-23 Zhou Haijun , Zhang Yang , Ou-Yang Zhong-can

Fundamental understanding of macroscopic properties of polymer nanocomposites (PNCs) remains difficult due to the complex interplay of microscopic dynamics and structure, namely interfacial layer relaxations and three-dimensional…

We consider weakly interacting diffusions on time varying random graphs. The system consists of a large number of nodes in which the state of each node is governed by a diffusion process that is influenced by the neighboring nodes. The…

Probability · Mathematics 2017-02-16 Shankar Bhamidi , Amarjit Budhiraja , Ruoyu Wu

Nanopore resistive pulse sensors are emerging technologies for single-molecule protein sequencing. But they can hardly detect small post-translational modifications (PTMs) such as hydroxylation in single-molecule level. While a combination…

Quantitative Methods · Quantitative Biology 2024-01-09 Mulusew W. Yaltaye , Yingqi Zhao , Eva Bozo , Pei-Lin Xin , Vahid Farrah , Francesco De Angelis , Jian-An Huang
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