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Although the disease-relevant microtubule-associated protein tau is known to severely inhibit kinesin-based transport in vitro, the potential mechanisms for reversing this detrimental effect to maintain healthy transport in cells remain…

Biomolecules · Quantitative Biology 2017-07-26 Jing Xu , Stephen J. King , Maryse Lapierre-Landry , Brian Nemec

When very small particles are suspended in a fluid in motion, they tend to follow the flow. How such tracer particles are mixed, transported, and dispersed by turbulent flow has been successfully described by statistical models. Heavy…

Fluid Dynamics · Physics 2023-12-21 J. Bec , K. Gustavsson , B. Mehlig

Molecular motors do not work in isolation {\it in-vivo}. We highlight some of the coordinations, cooperations and competitions that determine the collective properties of molecular motors in eukaryotic cells. In the context of traffic-like…

Biological Physics · Physics 2009-04-16 Debashish Chowdhury

Laparoscopy is an electrosurgical medical operation often involving an application of high-frequency alternating current to remove undesired biological tissue from the insufflated abdomen accessible through inlet and outlets trocars. One of…

The transport of lymph through the lymphatic vasculature is the mechanism for returning excess interstitial fluid to the circulatory system, and it is essential for fluid homeostasis. Collecting lymphatic vessels comprise a significant…

Fluid Dynamics · Physics 2021-07-06 Hallie Elich , Aaron Barrett , Varun Shankar , Aaron L. Fogelson

Due to inherent complexity active transport presents a landmark hurdle for oral absorption properties prediction. We present a novel approach carrier-mediated drug absorption parameters calculation based on entirely different paradigm than…

Quantitative Methods · Quantitative Biology 2008-10-16 P. O. Fedichev , T. V. Kolesnikova , A. A. Vinnik

Kinematic variables have been playing an important role in collider phenomenology, as they expedite discoveries of new particles by separating signal events from unwanted background events and allow for measurements of particle properties…

High Energy Physics - Phenomenology · Physics 2022-06-28 Roberto Franceschini , Doojin Kim , Kyoungchul Kong , Konstantin T. Matchev , Myeonghun Park , Prasanth Shyamsundar

The full understanding of cellular functions requires information about protein numbers for various biomolecular assemblies and their dynamics, which can be partly accessed by super-resolution fluorescence microscopy. Yet, many protein…

Biological Physics · Physics 2020-06-17 Kristin S. Grußmayer , Klaus Yserentant , Dirk-Peter Herten

A mathematical model for fluid and solute transport in peritoneal dialysis is constructed. The model is based on a three-component nonlinear system of two-dimensional partial differential equations for fluid, glucose and albumin transport…

Tissues and Organs · Quantitative Biology 2015-07-08 R. Cherniha , J. Stachowska-Pietka , J. Waniewski

We have developed a two dimensional stochastic molecular dynamics model for the description of intra cellular collective motion of bio motors, in particular Kinesins, on a microtubular track. The model is capable or reproducing the…

Soft Condensed Matter · Physics 2010-06-22 Yousef Jamali , M. Ebrahim Foulaadvand , H. Rafii Tabar

We describe a systematic development of kinetic entropy as a diagnostic in fully kinetic particle-in-cell (PIC) simulations and use it to interpret plasma physics processes in heliospheric, planetary, and astrophysical systems. First, we…

Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…

Applications · Statistics 2026-04-23 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

Transport of molecular motors along protein filaments in a half-closed geometry is a common feature of biologically relevant processes in cellular protrusions. Using a lattice gas model we study how the interplay between active and…

Biological Physics · Physics 2017-03-30 Isabella R. Graf , Erwin Frey

This paper introduces the use of statistical distributions based on transport differential equations for clear distinction of transport modes within transient kinetic experiments. More specifically,novel techniques are developed for the…

Applications · Statistics 2025-01-08 M. Ross Kunz , Debtanu Maiti , Gregory Yablonsky , Rebecca Fushimi

A study of the transport coefficients of a system of elastic hard disks, based on the use of Helfand-Einstein expressions is reported. The self-diffusion, the viscosity, and the heat conductivity are examined with averaging techniques…

Statistical Mechanics · Physics 2016-08-16 Ramón García-Rojo , Stefan Luding , J. Javier Brey

Laparoscopy is an operation carried out in the abdomen or pelvis through small incisions with external visual control by a camera. This technique needs the abdomen to be insufflated with carbon dioxide to obtain a working space for surgical…

Applications · Statistics 2023-10-06 Gabriel Calvo , Carmen Armero , Virgilio Gómez-Rubio , Guido Mazzinari

A mass transport directed from low to high density region in an inhomogeneous medium is modeled as a limiting case of a two-component lattice gas with excluded volume constraint and one of the components fixed. In the long-wavelength…

Disordered Systems and Neural Networks · Physics 2012-10-05 Sergei P. Lukyanets , Oleksandr V. Kliushnychenko

Using numerical simulations and analytical approximations we study a modified version of the two-dimensional lattice model [R. Piasecki,phys. stat. sol. (b) 209, 403 (1998)] for random pH:(1-p)L systems consisting of grains of high (low)…

Materials Science · Physics 2015-06-24 R. Piasecki

Markerless motion capture using computer vision and human pose estimation (HPE) has the potential to expand access to precise movement analysis. This could greatly benefit rehabilitation by enabling more accurate tracking of outcomes and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 R. James Cotton , Allison DeLillo , Anthony Cimorelli , Kunal Shah , J. D. Peiffer , Shawana Anarwala , Kayan Abdou , Tasos Karakostas

Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue. This paper is the first of a…

Quantitative Methods · Quantitative Biology 2018-08-21 Fabrice Delbary , Sara Garbarino , Valentina Vivaldi
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