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Diffusion magnetic resonance imaging (dMRI) data allow to reconstruct the 3D pathways of axons within the white matter of the brain as a tractography. The analysis of tractographies has drawn attention from the machine learning and pattern…

Machine Learning · Statistics 2015-04-03 Emanuele Olivetti , Thien Bao Nguyen , Paolo Avesani

Objective: Most deep neural network-based diffusion tensor imaging methods require the diffusion gradients' number and directions in the data to be reconstructed to match those in the training data. This work aims to develop and evaluate a…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Zejun Wu , Jiechao Wang , Zunquan Chen , Qinqin Yang , Zhen Xing , Dairong Cao , Jianfeng Bao , Taishan Kang , Jianzhong Lin , Shuhui Cai , Zhong Chen , Congbo Cai

Diffusion MRI tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections. White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Tengfei Xue , Fan Zhang , Chaoyi Zhang , Yuqian Chen , Yang Song , Alexandra J. Golby , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

AI-based vascular segmentation is becoming increasingly common in enhancing the screening and treatment of ophthalmic diseases. Deep learning structures based on U-Net have achieved relatively good performance in vascular segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Kai Huang , Nassir Navab , M. Ali Nasseri

Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often…

Neurons and Cognition · Quantitative Biology 2025-05-30 Xuhang Chen , Michael Kwok-Po Ng , Kim-Fung Tsang , Chi-Man Pun , Shuqiang Wang

Diffusion MRI offers a unique probe into neural microstructure and connectivity in the developing brain. However, analysis of neonatal brain imaging data is complicated by inevitable subject motion, leading to a series of scattered slices…

Deep learning based methods have achieved state-of-the-art performance for automated white matter (WM) tract segmentation. In these methods, the segmentation model needs to be trained with a large number of manually annotated scans, which…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Wan Liu , Qi Lu , ZhiZheng Zhuo , Yaou Liu , Chuyang Ye

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

Diffusion Tensor Imaging (DTI) tractography offers detailed insights into the structural connectivity of the brain, but presents challenges in effective representation and interpretation in deep learning models. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Vishwa Mohan Singh , Alberto Gaston Villagran Asiares , Luisa Sophie Schuhmacher , Kate Rendall , Simon Weißbrod , David Rügamer , Inga Körte

Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster, et al. showed that complex graph measures of the connectome,…

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Jakob Wasserthal , Peter Neher , Dusan Hirjak , Klaus H. Maier-Hein

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

Diffusion tensor imaging (DTI) has been used to study the effects of neurodegenerative diseases on neural pathways, which may lead to more reliable and early diagnosis of these diseases as well as a better understanding of how they affect…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 Chaoqing Xu , Tyson Neuroth , Takanori Fujiwara , Ronghua Liang , Kwan-Liu Ma

Automated segmentation of white matter hyperintensities (WMHs) is an essential step in neuroimaging analysis of Magnetic Resonance Imaging (MRI). Fluid Attenuated Inversion Recovery (FLAIR-weighted) is an MRI contrast that is particularly…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Martin Soria Røvang , Per Selnes , Bradley John MacIntosh , Inge Rasmus Groote , Lene Paalhaugen , Sudre Carole , Tormod Fladby , Atle Bjørnerud

Deep learning has shown great potential in accelerating diffusion tensor imaging (DTI). Nevertheless, existing methods tend to suffer from Rician noise and detail loss in reconstructing the DTI-derived parametric maps especially when…

Computer Vision and Pattern Recognition · Computer Science 2024-01-04 Wenxin Fan , Jian Cheng , Cheng Li , Xinrui Ma , Jing Yang , Juan Zou , Ruoyou Wu , Qiegen Liu , Shanshan Wang

Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Yui Lo , Yuqian Chen , Dongnan Liu , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

White matter tract integrity (WMTI) can characterize brain microstructure in areas with highly aligned fiber bundles. Several WMTI biomarkers have now been validated against microscopy and provided promising results in studies of brain…

The connectivity and structural integrity of the white matter of the brain is nowadays known to be implicated into a wide range of brain-related disorders. However, it was not before the advent of diffusion Magnetic Resonance Imaging (dMRI)…

Computer Vision and Pattern Recognition · Computer Science 2014-01-27 Q. Zhou , O. Michailovich , Y. Rathi

Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

Computational Engineering, Finance, and Science · Computer Science 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits