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Medical image synthesis is a challenging task due to the scarcity of paired data. Several methods have applied CycleGAN to leverage unpaired data, but they often generate inaccurate mappings that shift the anatomy. This problem is further…

Segmentation of magnetic resonance (MR) images is a fundamental step in many medical imaging-based applications. The recent implementation of deep convolutional neural networks (CNNs) in image processing has been shown to have significant…

In many clinical settings, the use of both Computed Tomography (CT) and Magnetic Resonance (MRI) is necessary to pursue a thorough understanding of the patient's anatomy and to plan a suitable therapeutical strategy; this is often the case…

Deep learning-based computer-aided diagnosis (CAD) of medical images requires large datasets. However, the lack of large publicly available labeled datasets limits the development of deep learning-based CAD systems. Generative Adversarial…

In this work, we study the problem of training deep networks for semantic image segmentation using only a fraction of annotated images, which may significantly reduce human annotation efforts. Particularly, we propose a strategy that…

Recently, the cycle-consistent generative adversarial networks (CycleGAN) has been widely used for synthesis of multi-domain medical images. The domain-specific nonlinear deformations captured by CycleGAN make the synthesized images…

Instance segmentation for unlabeled imaging modalities is a challenging but essential task as collecting expert annotation can be expensive and time-consuming. Existing works segment a new modality by either deploying a pre-trained model…

CT is commonly used in orthopedic procedures. MRI is used along with CT to identify muscle structures and diagnose osteonecrosis due to its superior soft tissue contrast. However, MRI has poor contrast for bone structures. Clearly, it would…

Medical Image Segmentation is a useful application for medical image analysis including detecting diseases and abnormalities in imaging modalities such as MRI, CT etc. Deep learning has proven to be promising for this task but usually has a…

Anatomical structures such as blood vessels in contrast-enhanced CT (ceCT) images can be challenging to segment due to the variability in contrast medium diffusion. The combined use of ceCT and contrast-free (CT) CT images can improve the…

Synthesized medical images have several important applications, e.g., as an intermedium in cross-modality image registration and as supplementary training samples to boost the generalization capability of a classifier. Especially,…

Analyzing medical data to find abnormalities is a time-consuming and costly task, particularly for rare abnormalities, requiring tremendous efforts from medical experts. Artificial intelligence has become a popular tool for the automatic…

Annotating nuclei in microscopy images for the training of neural networks is a laborious task that requires expert knowledge and suffers from inter- and intra-rater variability, especially in fluorescence microscopy. Generative networks…

In the field of radiotherapy, accurate imaging and image registration are of utmost importance for precise treatment planning. Magnetic Resonance Imaging (MRI) offers detailed imaging without being invasive and excels in soft-tissue…

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Generating realistic tissue images with annotations is a challenging task that is important in many computational histopathology applications. Synthetically generated images and annotations are valuable for training and evaluating…

Training medical image segmentation models for rare yet clinically important imaging modalities is challenging due to the scarcity of annotated data, and manual mask annotations can be costly and labor-intensive to acquire. This paper…

Cone beam computed tomography (CBCT) images can be used for dose calculation in adaptive radiation therapy (ART). The main challenges are the large artefacts and inaccurate Hounsfield unit (HU) values. Currently, deformed planning CT images…

Automatic segmentation of white matter hyperintensities in magnetic resonance images is of paramount clinical and research importance. Quantification of these lesions serve as a predictor for risk of stroke, dementia and mortality. During…

Ultrasound imaging is pivotal in various medical diagnoses due to its non-invasive nature and safety. In clinical practice, the accuracy and precision of ultrasound image analysis are critical. Recent advancements in deep learning are…