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Models of cortical neuronal circuits commonly depend on inhibitory feedback to control gain, provide signal normalization, and to selectively amplify signals using winner-take-all (WTA) dynamics. Such models generally assume that excitatory…

Neurons and Cognition · Quantitative Biology 2018-01-16 Ueli Rutishauser , Jean-Jacques Slotine , Rodney J. Douglas

The neural dynamics generating sensory, motor, and cognitive functions are commonly understood through field theories for neural population activity. Classic neural field theories are derived from highly simplified models of individual…

Neurons and Cognition · Quantitative Biology 2023-11-21 Gabriel Koch Ocker

Triggering a single additional spike in a cerebral cortical neuron was recently demonstrated to cause a cascade of extra spikes in the network that is likely to rapidly decorrelate the network's microstate. The mechanisms involved in this…

Neurons and Cognition · Quantitative Biology 2011-03-01 Michael Monteforte , Fred Wolf

The neocortex has a remarkably uniform neuronal organization, suggesting that common principles of processing are employed throughout its extent. In particular, the patterns of connectivity observed in the superficial layers of the visual…

Neurons and Cognition · Quantitative Biology 2011-05-17 Ueli Rutishauser , Rodney J. Douglas , Jean-Jacques Slotine

An approach to nonlinear dynamical modeling of interaction between conscious and automatic processes in the brain is proposed. Illustration of this approach on the nonlinear equation for the current density in the cortex is presented.…

Pattern Formation and Solitons · Physics 2007-05-23 E. A. Novikov

The branching process is the minimal model for propagation dynamics, avalanches and criticality, broadly used in neuroscience. A simple extension of it, adding inhibitory nodes, induces a much-richer phenomenology, including, an…

Statistical Mechanics · Physics 2022-07-08 Roberto Corral López , Victor Buendía , Miguel A. Muñoz

In a network of dynamical systems, concurrent synchronization is a regime where multiple groups of fully synchronized elements coexist. In the brain, concurrent synchronization may occur at several scales, with multiple ``rhythms''…

Neurons and Cognition · Quantitative Biology 2007-05-23 Quang-Cuong Pham , Jean-Jacques Slotine

Insight into how information can propagate within cortical networks is essential for a more complete understanding of neural dynamics and computation in complex networks. Networks with clustered connections have previously been shown to…

Neurons and Cognition · Quantitative Biology 2025-08-19 Abhijit Chakraborty , Greg Morrison

The cerebral cortex spontaneously displays different patterns of activity that evolve over time according to the brain state. Sleep, wakefulness, resting states, and attention are examples of a wide spectrum of physiological states that can…

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

Neurons and Cognition · Quantitative Biology 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

This chapter revisits the concept of excitability, a basic system property of neurons. The focus is on excitable systems regarded as behaviors rather than dynamical systems. By this we mean open systems modulated by specific interconnection…

Neurons and Cognition · Quantitative Biology 2017-04-18 Rodolphe Sepulchre , Guillaume Drion , Alessio Franci

Learning and decision making in the brain are key processes critical to survival, and yet are processes implemented by non-ideal biological building blocks which can impose significant error. We explore quantitatively how the brain might…

Neurons and Cognition · Quantitative Biology 2011-04-19 Jake Bouvrie , Jean-Jacques Slotine

Activity in neocortex exhibits a range of behaviors, from irregular to temporally precise, and from weakly to strongly correlated. So far there has been no single theoretical framework that could explain all these behaviors, leaving open…

Neurons and Cognition · Quantitative Biology 2015-11-03 Alexander Lerchner , Peter E. Latham

Recurrent networks of dynamic elements frequently exhibit emergent collective oscillations, which can display substantial regularity even when the individual elements are considerably noisy. How noise-induced dynamics at the local level…

Adaptation and Self-Organizing Systems · Physics 2017-01-04 Belen Sancristobal , Beatriz Rebollo , Pol Boada , Maria V. Sanchez-Vives , Jordi Garcia-Ojalvo

Although individual neurons and neural populations exhibit the phenomenon of representational drift, perceptual and behavioral outputs of many neural circuits can remain stable across time scales over which representational drift is…

Neuronal heterogeneity, characterized by the presence of a multitude of spiking neuronal patterns, is a widespread phenomenon throughout the nervous system. In particular, the brain exhibits strong variability among inhibitory neurons.…

Neurons and Cognition · Quantitative Biology 2024-12-02 Katiele V. P. Brito , Joana M. G. L. Silva , Claudio R. Mirasso , Fernanda S. Matias

In dynamical models of cortical networks, the recurrent connectivity can amplify the input given to the network in two distinct ways. One is induced by the presence of near-critical eigenvalues in the connectivity matrix W, producing large…

Neurons and Cognition · Quantitative Biology 2012-07-31 Guillaume Hennequin , Tim P. Vogels , Wulfram Gerstner

The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…

Neurons and Cognition · Quantitative Biology 2016-01-07 Sarah Feldt Muldoon , Fabio Pasqualetti , Shi Gu , Matthew Cieslak , Scott T. Grafton , Jean M. Vettel , Danielle S. Bassett

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

We are offering a particular interpretation (well within the range of experimentally and theoretically accepted notions) of neural connectivity and dynamics and discuss it as the data-and-process architecture of the visual system. In this…

Neurons and Cognition · Quantitative Biology 2014-07-08 Christoph von der Malsburg